Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Medicine and Health Sciences
Dermatophyte Growth And Degradation Of Human Stratum Corneum In Vitro (Pathogenesis Of Dermatophytosis)., Azam J. Samdani
Dermatophyte Growth And Degradation Of Human Stratum Corneum In Vitro (Pathogenesis Of Dermatophytosis)., Azam J. Samdani
Department of Medicine
Background: This study was carried out to determine growth of dermatophytes using human stratum corneum in vitro and the degrading effect of Keratinases (Proteinases) on stratum corneum for a complete understanding of the host parasite relationship.
Method: Trichophyton rubrum isolates derived from patients with tinea cruris infections were obtained from the Department of Medical Microbiology, University Hospital of Wales, U.K. Human stratum corneum sterilized with ethylene oxide was used as a nitrogen source in agar culture medium plates.
Result: Fungal growth took place in plates which contained human stratum corneum particles while there was no growth in the plates without …