Medicine and Health Sciences Commons^™

Establishment And Characterization Of Asian Oral Cancer Cell Lines As In Vitro Models To Study A Disease Prevalent In Asia, Hamid S., Lim K. P., Rosnah Binti Zain, Ismail S. M., Lau S. H., Mustafa W. M. W., Abraham M. T., Nam N. A., Teo S. H., Cheong S. C.

Prof. Dr. Rosnah Binti Zain

We have established 3 cell lines ORL-48, -115 and -136 from surgically resected specimens obtained from untreated primary human oral squamous cell carcinomas of the oral cavity. The in vitro growth characteristics, epithelial origin, in vitro anchorage independency, human papillomavirus (HPV) infection, microsatellite instability status, karyotype and the status of various cell cycle regulators and gatekeepers of these cell lines were investigated. All 3 cell lines grew as monolayers with doubling times ranging between 26.4 and 40.8 h and were immortal. Karyotyping confirmed that these cell lines were of human origin with multiple random losses and gains of entire chromosomes …

Evaluation Of Laser Treatment On Reline-Base Composites, Selda Keskin

No abstract provided.

Bond Strength Of A Silicone Soft Lining Material To Pol(Methyl Methacrylate) Resin Treated With Maleic Anhydride And Its Terpolymers, Selda Keskin

No abstract provided.

The Effect Of Esthetic Fibers On Impact Resistance Of A Conventional Heat-Cured Denture Base Resin, Selda Keskin

No abstract provided.

Flexural And Bonding Properties Of A Denture Base Polymer Treated With Nitric Acid Or Ultraviolet Radiation Before Relining With Molloplast-B, Selda Keskin

No abstract provided.

Tooth-Size Discrepancy And Bolton's Ratios: The Reproducibility And Speed Of Two Methods Of Measurement, Othman S. A., Harradine N. W.

Siti Adibah Othman

OBJECTIVE: To determine and compare the reproducibility and speed of two methods of performing Bolton's tooth-size analysis. DESIGN: Analysis of randomly selected clinical sample. SETTING: Bristol Dental Hospital, University of Bristol, United Kingdom. MATERIALS AND METHODS: Pre-treatment study casts of 150 patients were selected randomly from 1100 consecutively treated Caucasian orthodontic patients. Bolton tooth-size discrepancies and ratios were measured using two methods; one method employed entirely manual measurement and the Odontorule slide rule, while the other employed digital calipers and the HATS analysis software. Twenty study casts were measured twice, a week apart with both methods. Another three investigators also …

Warm Vertical Compaction Versus Lateral Compaction For Root Canal Obturation, Ahmed A. Madfa

Ahmed A. Madfa

Objectives: This study compared warm vertical compaction with lateral compaction for obturating root canals with either a polymer-based resin system or gutta-percha. Quality of obturation was evaluated by (i) analysis of the canal area occupied by filling core materials, sealers and voids at three cross-sectional levels and (ii) SEM examination. Methods: Single canals in 64 mandibular premolars were instrumented, irrigated and divided into four equal groups. They were root filled as follows: lateral compaction/resin (RealSeal™, SybronEndo) (LC/R), lateral compaction/gutta-percha with AH Plus™ (LC/GP), warm compaction/resin (WC/R) and warm compaction/gutta-percha (WC/GP). One specimen from each group, randomly chosen for SEM examination, …

Oral Lichen Planus And Lichenoid Reactions: Etiopathogenesis, Diagnosis, Management And Malignant Transformation, Ismail S. B., Kumar S. K., Rosnah Binti Zain

Prof. Dr. Rosnah Binti Zain

Lichen planus, a chronic autoimmune, mucocutaneous disease affects the oral mucosa (oral lichen planus or OLP) besides the skin, genital mucosa, scalp and nails. An immune mediated pathogenesis is recognized in lichen planus although the exact etiology is unknown. The disease most commonly affects middle-aged females. Oral lichenoid reactions (OLR) which are considered variants of OLP, may be regarded as a disease by itself or as an exacerbation of an existing OLP, by the presence of medication (lichenoid drug reactions) or dental materials (contact hypersensitivity). OLP usually presents as white striations (Wickham's striae), white papules, white plaque, erythema, erosions or …

An Adaptive Fuzzy Regression Model For The Prediction Of Dichotomous Response Variables, Dom R. M., Kareem S. A., Rosnah Binti Zain, Abldin B.

Prof. Dr. Rosnah Binti Zain

This paper proposes an adaptive technique in the prediction of dichotomous response variable by combining fuzzy concept with statistical logistic regression. The model was tested on an oral cancer dataset in predicting oral cancer susceptibility. In this paper we will present the development, evaluation and validation of the proposed model based on the experiment carried out. Explanatory power of the adaptive model was calculated and compared with fuzzy neural network and statistical logistic regression models using calibration and discrimination techniques. Area under ROC values calculated indicates that the proposed model has compatible predictive ability to both fuzzy neural network and …

Rolling Ball Contact As A Method For Testing Surface Fatigue Of Resin Based Restorative Materials, Noor Hayaty Abu Kasim Abu Kasim N.H.

Noor Hayaty Abu Kasim Abu Kasim N.H.

It has been recognised that compressive, tensile and flexural strength do not accurately determine the durability of dental restorations and that fatigue induced failure plays an important role. Fatigue caused by cyclic loading is thought to be responsible for the failure of composites restorations described by chipping, localized or generalized wear and fracture. The main aim of this work is to develop and evaluate the rolling ball contact as a method for testing surface fatigue of resin-based restorative materials. The results showed that material loss during the testing period mimic that of a fatigue failure process occurring in rolling elements. …

Silverfil: Its Physical Characterization, Noor Hayaty Abu Kasim Abu Kasim N.H.

Noor Hayaty Abu Kasim Abu Kasim N.H.

This article focuses on the physical characterization of Silverfil (R) amalgam. Analysis of the amalgamated material semi-quantitatively showed that Silverfil (R) comprised of approximately two thirds mercury and one third silver. No other elements were detected. Examination of the amalgamated material by x ray mapping and metallographically showed no evidence of free mercury present. Silverfil (R) has strong affinity towards the mercury ion. X-ray Diffraction analysis showed that the amalgamated Silverfil (R) is similar to a mineral in nature called "Moschellandsbergite". The advantages of Silverfil (R) over conventional amalgam were highlighted.

Fabrication Of 316l Stainless Steel Parts By Injection Moulding For Biomedical Application Using A Novel Binder, Noor Hayaty Abu Kasim Abu Kasim N.H.

Noor Hayaty Abu Kasim Abu Kasim N.H.

This paper focuses on the usage of a novel binder system base on palm oil product to produce sintered parts of stainless steel 316L produced by vertical injection molding technique for biomedical application. The stainless steel 316L powder was mixed using z-blade mixer with the thermoplastic binder system comprising of polyethylene, paraffin wax, stearic acid and palm stearin which was derived from palm oil at different volume percent (%). The feedstock then was studied in term of viscosity and shear rate using capillary rheometer. The feedstock was molded using vertical injection molding machine. After molding, the green molded part was …

Standardization Of Distance And Angulation Of Light Curing Unit Tip Using Distometer, Noor Hayaty Abu Kasim Abu Kasim N.H.

Noor Hayaty Abu Kasim Abu Kasim N.H.

The purpose of this study was to investigate the light intensity of selected light curing unit with varying distance and angulation of the light curing tip and lightmeter. Four types of light units; Spectrum 800 (Dentsply), Coltulux 3 (Coltene), Elipar FreeLight 2 (3M Espe) and Starlight Pro (Mectron) were evaluated for light intensity at various distance between the light curing tip and the lightometer Cure Rite Denstply (0, 1, 3, 5, 10 and 15 mm). The light curing units were angulated at 45 degrees, 60 degrees and 90 degrees at a standardized 5 mm distance. The intensity of light curing …