Medicine and Health Sciences Commons^™

Adenosquamous Carcinoma Of The Tongue, Yeshwant B. Rawal, Kenneth M. Anderson

School of Dentistry Faculty Research and Publications

A 51-year-old white female presented with a painful ulcer of the left ventrolateral tongue. An incisional biopsy confirmed a diagnosis of adenosquamous carcinoma. The adenosquamous carcinoma is an uncommon malignant tumor with histopathological features of a squamous carcinoma and an adenocarcinoma. A definitive diagnosis requires histopathological examination of a deep biopsy involving the submucosal tissue. This malignant tumor shows aggressive behavior with early invasive growth and a poor prognosis. The histopathological findings and differential diagnosis of a case of adenosquamous carcinoma of the tongue are discussed.

Impending Total Airway Collapse Involving A Maxillary Removable Partial Denture: A Clinical Report, Georgios Maroulakos, Stylianos Voulgarelis

School of Dentistry Faculty Research and Publications

This article presents a rare incident of a bilateral maxillary removable partial denture as an airway foreign body. The removable partial denture and the surrounding soft tissue irritation caused partial obstruction of the airway. Impending airway collapse was avoided after successful removal of the foreign body. Removing a removable dental prostheses at night, not only to prevent soft tissue pathology but also to avoid ingestion or aspiration of the prosthesis, must be emphasized.

Using Enamel Matrix Derivative To Improve Treatment Efficacy In Periodontal Furcation Defects, Reza Masaeli, Kavosh Zandsalimi, Zahra Lotfi, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Purpose

Furcations are complicated periodontal defects. Untreated furcations lead to loss of the involved teeth and supporting tissues. It has been demonstrated that regenerative biomaterials are beneficial in reconstruction of the bone surrounding furcation‐affected teeth. These biomaterials range from bone grafts and nonresorbable/resorbable barrier membranes to biologics that are able to trigger inactive regenerative processes in periodontal tissues. Selection of appropriate material(s) to treat furcations is challenging. The aim of this article is to provide a comparative outlook on different biomaterials applicable in regeneration of furcations with a focus on enamel matrix derivative (EMD).

Methods

Scientific databases including PubMed/MEDLINE, ScienceDirect, …

Management Of Cervical Root Fracture Injury In A Patient With Epilepsy: Case Report With 5-Year Follow-Up, Elif Ataol, Gizem Erbaş Ünverdi, H. Cem Güngör

School of Dentistry Faculty Research and Publications

The difficulty in providing stability to the coronal segment makes cervical root fracture one of the most challenging dental traumatic injury. This type of injury is less frequent in children. However, due to their serious consequences and poor prognosis, tooth loss may occur. This report presents the management of a case of cervical root fracture in an 11-year-old patient with epilepsy. The stabilization of the root-fractured tooth with a splint failed due to the recurrent seizures the patient had. Coronal fragment was removed and vital root submergence was performed in order to support the alveolar growth. The natural tooth crown …

In Vitro Effect Of Graphene Structures As An Osteoinductive Factor In Bone Tissue Engineering: A Systematic Review, Dorsa Mohammadrezaei, Hossein Golzar, Maryam Rezai Rad, Meisam Omidi, Hamid Rashedi, Fatemeh Yazdian, Arash Khojasteh, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Graphene and its derivatives have been well‐known as influential factors in differentiating stem/progenitor cells toward the osteoblastic lineage. However, there have been many controversies in the literature regarding the parameters effect on bone regeneration, including graphene concentration, size, type, dimension, hydrophilicity, functionalization, and composition. This study attempts to produce a comprehensive review regarding the given parameters and their effects on stimulating cell behaviors such as proliferation, viability, attachment and osteogenic differentiation. In this study, a systematic search of MEDLINE database was conducted for in vitro studies on the use of graphene and its derivatives for bone tissue engineering from January …

In Reply, Yeshwant B. Rawal, Joshua S. Brandner, Louis J. Kim, Jasjit K. Dillon

School of Dentistry Faculty Research and Publications

No abstract provided.

Orthodontic Open-Coil Spring Deactivation Forces Differ With Varying Activation Levels, Ryan Lubinsky

Master's Theses (2009 -)

Coil springs are used in orthodontics to deliver forces to move teeth. However, the optimal amount of activation to produce predictable, continuous deactivation forces, for the purpose of orthodontic tooth movement, is unclear. The purpose of this study was to evaluate the deactivation force characteristics of nickel-titanium open-coil springs after varying levels of activation. Methods: Four open-coil spring products were evaluated: Dentsply GAC 100 gram and 150 gram, Orthoclassic Orthodontics Medium 150 gram, and American Orthodontics nickel-titanium springs. Open-coil springs were compressed (activation) with a universal testing machine to 20, 40, 60, or 80% of original length (15 mm; n=15/product/activation …

Orthodontic Treatment Planning Using Direct Visual Approximation Of Arch Length Discrepancy And Cephalometric Analyses, Kathleen Rouse Vaught

Master's Theses (2009 -)

Introduction: Space analysis and radiographic analyses are crucial elements in developing an orthodontic treatment plan. It is imperative that the orthodontist makes accurate measurements in order to come up with the most effective treatment options for each patient. Some practitioners refrain from direct measurements to determine arch length discrepancies and instead determine the amount of crowding by using direct visual approximation. In addition, more orthodontists do not routinely trace all cephalograms taken. If more and more orthodontists are using direct visual approximation to determine angular cephalometric measurements, it is important to assess the accuracy and reliability of these measurements. This …

Orthodontic Bond Strength Comparison Between Two Filled Resin Sealants, James Kolstad

Master's Theses (2009 -)

Introduction: Sealants are used in orthodontics to help prevent demineralization during treatment. The objective of this study was to determine if there is a difference in the shear bond strength (SBS) between two different resin sealants bonded to teeth. Materials and Methods: Extracted human premolars (n=20/group) were randomly divided and prepared by acid etching, followed by application of primer or sealant. Group 1, the control group, used Transbond XT Primer (3M Unitek). Groups 2 and 3 were prepared with the sealants L.E.D. Pro Seal (Reliance Orthodontic Products) and Opal Seal (Opal Orthodontics) respectively. Transbond XT Adhesive was applied to a …

Comparison Of Immediate Vs. Delayed Recall Of Orthodontic Information Following An Electronic Reminder, Michael Lenz

Master's Theses (2009 -)

Patients and parents in dentistry often do not remember important information disclosed during the informed consent process, so improvement in the delivery of information is needed. This study explored the effect of an emailed narrated instructional PowerPoint on the immediate vs. delayed recall and comprehension of informed consent information in orthodontics. Thirty-two subjects were recruited from a university and private practice orthodontic clinic. At the initial visit, subjects were alternately assigned to one of two groups and were presented with a mock orthodontic treatment plan and informed consent presentation for a pretend patient. Immediately following the presentation, the subjects’ verbal …

Application Of Mechanical Vibration To Enhance The Stability After Orthodontic Treatment - A Micro - Ct Study, Nicolas Branshaw

Master's Theses (2009 -)

Introduction: Mechanical vibration (MV) possesses anti-resorptive properties that can possibly enhance the stability of the dentition during retention, lessening the potential for relapse of teeth to their initial positions. In this project, we established a mouse model and investigated the effects of MV on bone modeling during orthodontic retention. Materials and Methods: Thirty-two 14-week-old inbred strain C57BL/6 male mice were randomly assigned into four groups: 1) Control (N=6); 2) Mechanical Vibration (MV) (N =6); 3) Orthodontic Retention (OR) (N=9); and 4) Orthodontic Retention and Mechanical Vibration (ORMV) (N=11). All mice in OR and ORMV groups received approximately 10g of orthodontic …

Dextran Hydrogels Incorporated With Bioactive Glass-Ceramic: Nanocomposite Scaffolds For Bone Tissue Engineering, Parisa Nikpour, Hamed Salimi-Kenari, Farahnaz Fahimipour, Sayed Mahmood Rabiee, Mohammad Imani, Erfan Dashtimoghadam, Lobat Tayebi

School of Dentistry Faculty Research and Publications

A series of nanocomposite scaffolds comprised of dextran (Dex) and sol–gel derived bioactive glass ceramic nanoparticles (nBGC: 0–16 (wt%)) were fabricated as bioactive scaffolds for bone tissue engineering. Scanning electron microscopy showed Dex/nBGC scaffolds were consisting of a porous 3D microstructure with an average pore size of 240 μm. Energy-dispersive x-ray spectroscopy illustrated nBGC nanoparticles were homogenously distributed within the Dex matrix at low nBGC content (2 wt%), while agglomeration was observed at higher nBGC contents. It was found that the osmotic pressure and nBGC agglomeration at higher nBGC contents leads to increased water uptake, then reduction of the compressive …

Quality Of Postoperative Pain Management After Maxillofacial Fracture Repair, Andre Peisker, Winfried Meissner, Gregor F. Raschke, Mina D. Fahmy, Arndt Guentsch, Juliane Schiller, Stefan Schultze-Mosgau

School of Dentistry Faculty Research and Publications

Background: Effective pain management is an essential component in the perioperative care of surgical patients. However, post-operative pain after maxillofacial fracture repair and its optimal therapy has not been described in detail.

Materials and Methods: In a prospective cohort study, 95 adults rated their pain on the first postoperative day after maxillofacial fracture repair using the questionnaire of the Quality Improvement in Postoperative Pain Management (QUIPS) project. Quality Improvement in Postoperative Pain Management allowed for a standardized assessment of patients’ characteristics and pain- related parameters.

Results: Overall, the mean maximal pain and pain on activity (numeric rating scales) were significantly …

Oral Sciences Phd Program Enrollment, Graduates, And Placement: 1994 To 2016, C. R. Herzog, David W. Berzins, P. Denbesten, R. L. Gregory, K. M. Hargreaves, R. L.W. Messer, M. Mina, M. P. Mooney, M. L. Paine, C. Phillips, R. B. Presland, R. G. Quivey, F. A. Scannapieco, J F. Sheridan, K. K.H. Svoboda, P. C. Trackman, M. P. Walker, S. G. Walker, C. Y. Wang, J. C.C. Hu

School of Dentistry Faculty Research and Publications

For decades, dental schools in the United States have endured a significant faculty shortage. Studies have determined that the top 2 sources of dental faculty are advanced education programs and private practice. Those who have completed both DDS and PhD training are considered prime candidates for dental faculty positions. However, there is no national database to track those trainees and no evidence to indicate that they entered academia upon graduation. The objective of this study was to assess outcomes of dental school–affiliated oral sciences PhD program enrollment, graduates, and placement between 1994 and 2016. Using the American Dental Association annual …

A Hemispherical Contact Model For Simplifying 3d Occlusal Surfaces, Miguel Castro-Garcia, Pedro Ángel Moreno-Cabello, Miguel Ángel Rubio-Paramio, Pilar Carranza-Cañadas, Geoffrey A. Thompson

School of Dentistry Faculty Research and Publications

Statement of problem

Currently, dental articulators can recreate mandibular movements and occlusal contacts. However, whether virtual articulators can also provide information about occluding dental surfaces, functional movements, and the mandibular condyles is unclear.

Purpose

The purpose of this in vitro study was to evaluate the occluding surfaces on dental casts obtained from a patient and approximate them to a hemispherical contact model. Both models were tested by digitizing the Dentatus ARL dental articulator.

Material and methods

A combination of photogrammetry and structure from motion methods were used to scan a Dentatus ARL articulator and representative dental casts. Using computer-aided engineering …

Clinical Long-Term Success Of Contemporary Nano-Filled Resin Composites In Class I And Ii Restorations Cured By Led Or Halogen Light, Torsten Pflaum, Stefan Kranz, Regina Montag, Arndt Guentsch, Andrea Völpel, Robin Mills, Klaus Jandt, Bernd Sigusch

School of Dentistry Faculty Research and Publications

Objectives

The use of LED light-curing units (LED LCUs) for polymerising resin-based composite restorations has become widespread throughout dentistry. Unfortunately, there is a paucity of clinical longitudinal studies that evaluate the comparative efficacy of LED-based polymerisation in direct posterior composite restorations. The aim of the present study was to investigate the performance of class I and II resin composite restorations for two successful composite restorative materials cured with LED versus halogen LCUs.

Methods

One hundred restorations were placed using the nano-filled composites Grandio® or Filtek™ Supremé. The following test groups were established: LED-Grandio® n = 23 (LG), LED-Filtek™ Supremé n …

Analysis Of Flexural Strength And Contact Pressure After Simulated Chairside Adjustment Of Pressed Lithium Disilicate Glass-Ceramic, Ali Ramadhan, Geoffrey A. Thompson, Georgios Maroulakos, David W. Berzins

School of Dentistry Faculty Research and Publications

Statement of problem

Research evaluating load-to-failure of pressed lithium disilicate glass-ceramic (LDGC) with a clinically validated test after adjustment and repair procedures is scarce.

Purpose

The purpose of this in vitro study was to investigate the effect of the simulated chairside adjustment of the intaglio surface of monolithic pressed LDGC and procedures intended to repair damage.

Material and methods

A total of 423 IPS e.max Press (Ivoclar Vivadent AG) disks (15 mm diameter, 1 mm height) were used in the study. The material was tested by using an equibiaxial loading arrangement (n≥30/group) and a contact pressure test (n≥20/group). Specimens were …

Comparison Of Different Temperatures On Bending Properties Of Six Niti Endodontic File Systems, Sukbum Yoo

Master's Theses (2009 -)

Introduction: Manufacturers claim that modern NiTi files with proprietary heat treatment transform at higher temperatures, thus staying more martensite and being more resistant to cyclic fatigue and more flexible. There are some studies comparing the effect of body temperature and room temperature on cyclic fatigue of these newer NiTi files. However, there is not yet a study published for evaluating the relationship between bending properties of NiTi instruments and temperature following the ISO 3630-1 guideline. The objective of this study was to evaluate how temperature affects the bending properties of six different brands of NiTi rotary instruments with different transformation …

Factors Effecting Survival Of Teeth With Nonsurgical Root Canal Therapy Including A Multi-State Outcome Analysis, Alex Moore

Master's Theses (2009 -)

Objective: To study the factors effecting the survival of teeth with non-surgical root canal therapy (NS-RCT) and to compare the transitions between failure states for teeth treated with NS-RCT based on initial provider type. Methods: Insurance claims were analyzed for 438,487 initial NS-RCT procedures to determine the effect of provider type, patient age, tooth position, presence of post/core, and crown at 90 days on tooth survival. Kaplan Meier survival estimates were evaluated for 1, 3, 5, and 10 years and adjusted hazard ratios (aHR’s) were calculated. A multi-state model with six transitions was created using the ‘mstate’ R package. Results: …

Effect Of Different Finish Line Designs On The Marginal And Internal Fit Of Metal Copings Made By Selective Laser Melting Technology, Adel Al Maaz

Master's Theses (2009 -)

Introduction: Marginal fit has been defined as the gap between the prepared tooth and the intaglio surface of the restoration. Internal gap is the perpendicular measurement from the internal surface of the casting to the axial wall of the preparation. Selective laser melting has been used for fabrication of metal copings such as Co-Cr base alloys and Au-Pt noble alloys. The purpose of this study was to determine the effect of different finish line designs on the marginal and internal fit of metal copings made from high noble, 25% noble and base alloys manufactured by SLM technology. Material and Methods: …

Effect Of Emergence Profile Of A Single Implant Restoration On The Health Of Peri-Implant Soft Tissue, Waleed Nasir Asiri

Master's Theses (2009 -)

Purpose: The specific aims of this retrospective study were 1) to compare the emergence angle of a single implant crown (SIC) of the mandibular first molar to the emergence angle of the natural contralateral tooth, 2) to evaluate the effect of the emergence angle of SIC on the health of the peri-implant soft tissue and 3) to quantify an acceptable emergence angle among SIC. Materials and methods: Ten Marquette University School of Dentistry (MUSoD) patients were included in the study. Each patient was examined clinically and plaque index (PI), probing depth (PD), and bleeding on probing (BOP) measurements were gathered …

A Retrospective Analysis Of Patient Medical And Dental Treatment Histories, And Mronj-Related Events, Jon Irelan

Master's Theses (2009 -)

With patient medical histories continuing to increase in complexity, dental professionals are faced with the task of delivering necessary care while respecting said medical history. Though advances have been made in combating osteopathies like osteoporosis and bone-related malignancies through medicinal intervention, these same medications can alter the bone’s ability to heal properly. The result of this inability to heal can be medication-related osteonecrosis of the jaw (MRONJ). The purpose of this study was to evaluate whether patients at risk for MRONJ treated at Marquette University School of Dentistry (MUSoD) demonstrated any complications following endodontic therapies associated with MRONJ. During the …

Trends In Self‐Reported Oral Health Of Us Adults: National Health And Nutrition Examination Survey 1999‐2014, Kar Yan Li, Christopher Okunseri, Colman Mcgrath, May C.M. Wong

School of Dentistry Faculty Research and Publications

Objective

Single‐item self‐reported oral health (SROH) is a convenient and reliable measure for the assessment of population‐based oral health. However, little is known about trends and its associations among US adults. This study investigated trends in SROH (aged 20+ years) and the associated factors among adults living in the United States.

Methods

Self‐reported oral health data for 41 621 adults aged 20+ years from the National Health and Nutrition Examination Survey (NHANES) 1999 to 2014 were analysed. Survey‐weighted descriptive statistics were computed to provide nationally representative estimates. Multivariable logistic regression was performed separately for each survey period with SROH as …

Immunohistochemical Expression Of Tlr-4 In Temporomandibular Joint Dysfunction, Luis Eduardo Almeida, Kyle Hresko, Adam Sorenson, Seth Butcher, Lobat Tayebi, Rosalia Leonardi, Carla Loreto, Jose A. Bosio, Flavio Camejo, Andrea Doetzer

School of Dentistry Faculty Research and Publications

Objective

Toll-like receptor 4 (TLR-4) is a transmembrane protein involved in the innate immune system and has been implicated in the pathogenesis of temporomandibular joint dysfunction (TMD). The purpose of this study was to histologically examine the level of expression of TLR-4 relative to severity of TMD.

Methods

Thirty-one human TMJ disc samples were immunostained for TLR-4 and evaluated for intensity of stain. Among the samples, 8 were control samples, 16 were from patients with anterior disc displacement with reduction (ADDwR), and 7 were from patients with anterior disc displacement without reduction (ADDwoR).

Results

There was no statistically significant difference …

The Effect Of Partially Exposed Connective Tissue Graft On Root‐Coverage Outcomes: A Systematic Review And Meta‐Analysis, Austin Dodge, Jeffrey Garcia, Paul Luepke, Yu-Lin Lai, Moawia M. Kassab, Guo-Hao Lin

School of Dentistry Faculty Research and Publications

The aim of this systematic review was to compare the root‐coverage outcomes of using a partially exposed connective tissue graft (CTG) technique with a fully covered CTG technique for root coverage. An electronic search up to February 28^th, 2017, was performed to identify human clinical studies with data comparing outcomes of root coverage using CTG, with and without a partially exposed graft. Five clinical studies were selected for inclusion in this review. For each study, the gain of keratinized gingiva, reduction of recession depth, number of surgical sites achieving complete root coverage, percentage of root coverage, gain of …

Trends And Racial/Ethnic Disparities In Antibiotic Prescribing Practices Of Dentists In The United States, Christopher Okunseri, C. Zheng, C. N. Steinmetz, Elaye Okunseri, Aniko Szabo

School of Dentistry Faculty Research and Publications

Objective

The aim of this study was to examine trends and racial/ethnic disparities in antibiotic prescribing practices of dentists in the United States.

Methods

The US Medical Expenditure Panel Survey data for 1996‐2013 was analyzed. Information on patient sociodemographic characteristics, dental visits, receipt of dental procedures, and type of antibiotics prescribed following visits was obtained. Descriptive statistics were calculated separately for each year. Logistic regression analyses were conducted to identify associations during the period with and without adjustment for dental procedures and sociodemographic characteristics. Survey weights were incorporated to handle the sampling design.

Results

Nationally, the number of antibiotic prescribed …

Role Of Dentists In Prescribing Opioid Analgesics And Antibiotics: An Overview, Ralph Dana, Amir Azarpazhooh, Nima Laghapour, Katie J. Suda, Christopher Okunseri

School of Dentistry Faculty Research and Publications

No abstract provided.

Oral Health Practices, Beliefs And Dental Service Utilization Of Albanian Immigrants In Milwaukee, Wisconsin: A Pilot Study, K. Rota, C. Spanbauer, Aniko Szabo, Christopher Okunseri

School of Dentistry Faculty Research and Publications

There is limited information on the oral health of Albanian immigrant population residing in the U.S. This creates a hinderance to developing and implementing appropriate dental care programs for the population. This study investigated oral health practices, beliefs, dental visits and associated factors of Albanian adults living in Milwaukee, Wisconsin. Purposive and snowball sampling methods were employed. Self-administered questionnaires were used to collect data on oral health practices, beliefs, dental visits and socio-demographic information. Descriptive and multivariable logistics regression were conducted. Overall, 266 adults were recruited, 54% male, 56% have lived 10 or more years in the U.S., 95% rated …

Nanomagnetic-Mediated Drug Delivery For The Treatment Of Dental Disease, Yadong Ji, Seung K. Choi, Ahmed S. Sultan, Kong Chuncai, Xiaoying Lin, Erfan Dashtimoghadam, Mary Anne Melo, Michael Weir, Huakun Xu, Lobat Tayebi, Ahihong Nie, Didier A. Depireux, Radi Masri

School of Dentistry Faculty Research and Publications

Maintaining the vitality of the dental pulp, the highly innervated and highly vascular, innermost layer of the tooth, is a critical goal of any dental procedure. Upon injury, targeting the pulp with specific therapies is challenging because it is encased in hard tissues. This project describes a method that can effectively deliver therapeutic agents to the pulp. This method relies on the use of nanoparticles that can be actively steered using magnetic forces to the pulp, traveling through naturally occurring channels in the dentin (the middle layer of the tooth). This method can reduce the inflammation of injured pulp and …

Intraosseous Hemangioma Of The Frontal Bone. Report Of A Case And Review Of The Literature, Joshua S. Brandner, Yeshwant B. Rawal, Louis J. Kim, Jasjit K. Dillon

School of Dentistry Faculty Research and Publications

Intraosseous hemangiomas of the maxillofacial region are rare lesions that constitute less than 1% of all osseous tumors. A review of the literature on intraosseous hemangiomas of the skull and facial bones showed a limited number of publications, much of which were largely limited to case reports. This case report summarizes the workup and surgical treatment of a 39-year-old woman with an intraosseous hemangioma of the left frontal bone. The histology, treatment, and literature are reviewed.