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Full-Text Articles in Medicine and Health Sciences
A Review On The Biodistribution, Pharmacokinetics And Toxicity Of Bismuth-Based Nanomaterials, Samireh Badrigilan, Fatemeh Heydarpanahi, Jalal Choupani, Mehdi Jaymand, Hadi Samadian, Mojtaba Hoseini-Ghahfarokhi, Thomas J. Webster, Lobat Tayebi
A Review On The Biodistribution, Pharmacokinetics And Toxicity Of Bismuth-Based Nanomaterials, Samireh Badrigilan, Fatemeh Heydarpanahi, Jalal Choupani, Mehdi Jaymand, Hadi Samadian, Mojtaba Hoseini-Ghahfarokhi, Thomas J. Webster, Lobat Tayebi
School of Dentistry Faculty Research and Publications
Here, bismuth-based nanomaterials (Bi-based NMs) are introduced as promising theranostic agents to enhance image contrast as well as for the therapeutic gain for numerous diseases. However, understanding the interaction of such novel developed nanoparticles (NPs) within a biological environment is a requisite for the translation of any promising agent from the lab bench to the clinic. This interaction delineates the fate of NPs after circulation in the body. In an ideal setting, a nano-based therapeutic agent should be eliminated via the renal clearance pathway, meanwhile it should have specific targeting to a diseased organ to reach an effective dose and …
Bismuth-Based Nanomaterials: Recent Advances In Tumor Targeting And Synergistic Cancer Therapy Techniques, Samireh Badrigilan, Jalal Choupani, Hashem Khanbabaei, Mojtaba Hoseini-Ghahfarokhi, Thomas J. Webster, Lobat Tayebi
Bismuth-Based Nanomaterials: Recent Advances In Tumor Targeting And Synergistic Cancer Therapy Techniques, Samireh Badrigilan, Jalal Choupani, Hashem Khanbabaei, Mojtaba Hoseini-Ghahfarokhi, Thomas J. Webster, Lobat Tayebi
School of Dentistry Faculty Research and Publications
Despite all of the efforts in the field of cancer therapy, the heterogeneous properties of tumor cells induce an insufficient therapeutic outcome when treated with conventional monotherapies, necessitating a shift in cancer treatment from monotherapy to combination therapy for complete cancer treatment. Multifunctional bismuth (Bi)-based nanomaterials (NMs) with therapeutic functions hold great promise for the fields of cancer diagnosis and therapy based on their low toxicity, X-ray sensitive capabilities, high atomic number, near-infrared driven semiconductor properties, and low cost. Herein, a comprehensive review of recent advances in various medicinal aspects of Bi-based NMs is presented including: evaluation of in-tumor site …