Medicine and Health Sciences Commons^™

Three-Dimensional Bio-Printing And Bone Tissue Engineering: Technical Innovations And Potential Applications In Maxillofacial Reconstructive Surgery, Muhja Salah, Lobat Tayebi, Keyvan Moharamzadeh, Farhad B. Naini

School of Dentistry Faculty Research and Publications

Background

Bone grafting has been considered the gold standard for hard tissue reconstructive surgery and is widely used for large mandibular defect reconstruction. However, the midface encompasses delicate structures that are surrounded by a complex bone architecture, which makes bone grafting using traditional methods very challenging. Three-dimensional (3D) bioprinting is a developing technology that is derived from the evolution of additive manufacturing. It enables precise development of a scaffold from different available biomaterials that mimic the shape, size, and dimension of a defect without relying only on the surgeon’s skills and capabilities, and subsequently, may enhance surgical outcomes and, in …