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Association Between Caries, Obesity And Insulin Resistance In Mexican Adolescents, Juan Pablo Loyola-Rodgriguez, Carlos Villa-Chavez, Nuria Patiño-Marin, Celia Aradillas-Garcia, Cesar Gonzalez, Esperanza De La Cruz-Mendoza

School of Dentistry Faculty Research and Publications

Aim: To determine the association among dental caries, obesity and insulin resistance in Mexican adolescents. Methods: Body Mass Index, obesity (OB) blood pressure, insulin level, insulin resistance (IR), triglycerides level, serum HDL-cholesterol (cHDL), DMFT index and salivary flow were measured. Results: Anthropometric measures showed a significant statistical difference (p < 0.05). Insulin level was 8.98 for healthy subjects, whereas for OB-IR group was 25.35, there was a statistical significant difference (p < 0.05). Triglycerides level was 88.50 for healthy subjects and 169.40 mg/dL for OB-IR; cHDL was 52.88 for healthy and 41.82 mg/dL for OB-IR group, both showed a statistically significant difference (p < 0.05). Salivary flow was 4.30 for healthy and for OB-IR group was 5.48 ml/min showed a significant statistical difference (p < 0.05). DMFT index was 3.02 for healthy and for OB-IR adolescents was 4.78, showed a significant statistical difference (p < 0.05). The caries component of DMFT index was 1.84 for healthy and was 3.52 for OB-IR adolescents, showed a significant statistical difference (p < 0.05). According to the multivariate analysis, DMFT (OR=3.10; IC95%=0.20-1.02, p=0.042) and decay (OR=3.30; IC95%=0.19-1.0, p=0.011) were associated with subjects with OB-IR. Conclusion: OB-IR Mexican adolescents showed a positive association with DMFT.