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A disintegrin and metalloproteinase domain 9; Biological Markers; Immunohistochemistry; Oral lichen planus; Proliferating cell nuclear antigen
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Full-Text Articles in Medicine and Health Sciences
An Inverse Relationship Between A Disintegrin And Metalloproteinase-9 And Proliferating Cell Nuclear Antigen Expression In Oral Lichen Planus, Darussakorn Maneerat, Pareena Chotjumlong, Thanapat Sastraruji, Surawut Pongsiriwet, Anak Iamaroon, Suttichai Krisanaprakornkit
An Inverse Relationship Between A Disintegrin And Metalloproteinase-9 And Proliferating Cell Nuclear Antigen Expression In Oral Lichen Planus, Darussakorn Maneerat, Pareena Chotjumlong, Thanapat Sastraruji, Surawut Pongsiriwet, Anak Iamaroon, Suttichai Krisanaprakornkit
Chulalongkorn University Dental Journal
Background A Disintegrin and Metalloproteinase-9 (ADAM-9) is a type I transmembrane protein associated with epithelial differentiation. ADAM-9 is involved in wound healing process by controlling keratinocyte migration and tumorigenesis. Proliferating cell nuclear antigen (PCNA) is a useful marker for cell proliferation. Several studies reported increased PCNA expression in oral lichen planus (OLP), but ADAM-9 expression in OLP has not yet been studied. Objectives To compare the expression of ADAM-9 and PCNA in OLP with that in normal oral mucosa and to find correlations between ADAM-9 or PCNA expression and OLP clinical severity. Materials and Methods The expression of ADAM-9 and …