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Full-Text Articles in Medicine and Health Sciences

Clinical Diagnosis Support With Convolutional Neural Network By Transfer Learning, Spencer Fogleman, Jeremy Otsap, Sangrae Cho Dec 2021

Clinical Diagnosis Support With Convolutional Neural Network By Transfer Learning, Spencer Fogleman, Jeremy Otsap, Sangrae Cho

SMU Data Science Review

Breast cancer is prevalent among women in the United States. Breast cancer screening is standard but requires a radiologist to review screening images to make a diagnosis. Diagnosis through the traditional screening method of mammography currently has an accuracy of about 78% for women of all ages and demographics. A more recent and precise technique called Digital Breast Tomosynthesis (DBT) has shown to be more promising but is less well studied. A machine learning model trained on DBT images has the potential to increase the success of identifying breast cancer and reduce the time it takes to diagnose a patient, …


Determining States Of Movement In Humans Using Minimally Processed Eeg Signals And Various Classification Methods, Maurice Barnett Dec 2021

Determining States Of Movement In Humans Using Minimally Processed Eeg Signals And Various Classification Methods, Maurice Barnett

All Theses

Electroencephalography (EEG) is a non-invasive technique used in both clinical and research settings to record neuronal signaling in the brain. The location of an EEG signal as well as the frequencies at which its neuronal constituents fire correlate with behavioral tasks, including discrete states of motor activity. Due to the number of channels and fine temporal resolution of EEG, a dense, high-dimensional dataset is collected. Transcranial direct current stimulation (tDCS) is a treatment that has been suggested to improve motor functions of Parkinson’s disease and chronic stroke patients when stimulation occurs during a motor task. tDCS is commonly administered without …


High-Dimensional Feature Selection And Multi-Level Causal Mediation Analysis With Applications To Human Aging And Cluster-Based Intervention Studies, Hachem Saddiki Oct 2021

High-Dimensional Feature Selection And Multi-Level Causal Mediation Analysis With Applications To Human Aging And Cluster-Based Intervention Studies, Hachem Saddiki

Doctoral Dissertations

Many questions in public health and medicine are fundamentally causal in that our objective is to learn the effect of some exposure, randomized or not, on an outcome of interest. As a result, causal inference frameworks and methodologies have gained interest as a promising tool to reliably answer scientific questions. However, the tasks of identifying and efficiently estimating causal effects from observed data still pose significant challenges under complex data generating scenarios. We focus on (1) high-dimensional settings where the number of variables is orders of magnitude higher than the number of observations; and (2) multi-level settings, where study participants …


Enhancing Microbiome Host Disease Prediction With Variational Autoencoders, Celeste Manughian-Peter Aug 2021

Enhancing Microbiome Host Disease Prediction With Variational Autoencoders, Celeste Manughian-Peter

Computational and Data Sciences (MS) Theses

Advancements in genetic sequencing methods for microbiomes in recent decades have permitted the collection of taxonomic and functional profiles of microbial communities, accelerating the discovery of the functional aspects of the microbiome and generating an increased interest among clinicians in applying these techniques with patients. This advancement has coincided with software and hardware improvements in the field of machine learning and deep learning. Combined, these advancements implicate further potential for progress in disease diagnosis and treatment in humans. The ability to classify a human microbiome profile into a disease category, and additionally identify the differentiating factors within the profile between …


Machine Learning In The Health Industry: Predicting Congestive Heart Failure And Impactors, Alexandra Norman, James Harding, Daria Zhukova May 2021

Machine Learning In The Health Industry: Predicting Congestive Heart Failure And Impactors, Alexandra Norman, James Harding, Daria Zhukova

SMU Data Science Review

Cardiovascular diseases, Congestive Heart Failure in particular, are a leading cause of deaths worldwide. Congestive Heart Failure has high mortality and morbidity rates. The key to decreasing the morbidity and mortality rates associated with Congestive Heart Failure is determining a method to detect high-risk individuals prior to the development of this often-fatal disease. Providing high-risk individuals with advanced knowledge of risk factors that could potentially lead to Congestive Heart Failure, enhances the likelihood of preventing the disease through implementation of lifestyle changes for healthy living. When dealing with healthcare and patient data, there are restrictions that led to difficulties accessing …