Medicine and Health Sciences Commons^™

The Effect Of Pesticide Spray Season And Residential Proximity To Agriculture On Glyphosate Exposure Among Pregnant People In Southern Idaho, 2021, Cynthia L. Curl, Carly Hyland, Meredith Spivak, Lianne Sheppard, Bruce Lanphear, Michael N. Antoniou, Maria Ospina, Antonia M. Calafat

Public Health and Population Science Faculty Publications and Presentations

Background: Glyphosate is one of the most heavily used pesticides in the world, but little is known about sources of glyphosate exposure in pregnant people living in agricultural regions.

Objective: Our objective was to evaluate glyphosate exposure during pregnancy in relation to residential proximity to agriculture as well as agricultural spray season.

Methods: We quantified glyphosate concentrations in 453 urine samples collected biweekly from a cohort of 40 pregnant people in southern Idaho from February through December 2021. We estimated each participant’s glyphosate exposure as the geometric mean (GM) of glyphosate concentrations measured in all samples (average n = 11 …

Urinary Glyphosate Concentrations Among Pregnant Participants In A Randomized, Crossover Trial Of Organic And Conventional Diets, Carly Hyland, Meredith Spivak, Lianne Sheppard, Bruce P. Lanphear, Michael Antoniou, Maria Ospina, Antonia M. Calafat, Cynthia L. Curl

Public Health and Population Science Faculty Publications and Presentations

Background: Consumption of an organic diet reduces exposure to a range of agricultural pesticides. Only three studies have examined the effect of an organic diet intervention on exposure to the herbicide glyphosate, the most heavily used agricultural chemical in the world. Despite its widespread use, the primary sources of glyphosate exposure in humans are poorly understood.

Objective: Our objective was to examine the effect of an organic diet intervention on urinary glyphosate concentrations among pregnant individuals.

Methods: We conducted a 2-wk randomized crossover trial in which 39 pregnant participants living near (≤ 0.5 km) or far (> 0.5 km) from …

Prenatal And Childhood Exposure To Organophosphate Pesticides And Behavior Problems In Adolescents And Young Adults In The Chamacos Study, Sharon K. Sagiv, Ana M. Mora, Stephen Rauch, Katherine R. Kogut, Carly Hyland, Robert B. Gunier, Asa Bradman, Julianna Deardorff, Brenda Eskenazi

Public Health and Population Science Faculty Publications and Presentations

Background: We previously reported associations of prenatal exposure to organophosphate (OP) pesticides with poorer neurodevelopment in early childhood and at school age, including poorer cognitive function and more behavioral problems, in the Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS), a birth cohort study in an agriculture community.

Objective: We investigated the extent to which early-life exposure to OP pesticides is associated with behavioral problems, including mental health, in youth during adolescence and early adulthood.

Methods: We measured urinary dialkylphosphates (DAPs), nonspecific OP metabolites, in urine samples collected from mothers twice during pregnancy (13 and 26 …

Possible Role Of Caffeine In Nicotine Use Onset Among Early Adolescents: Evidence From The Young Mountaineer Health Study Cohort, Alfgeir L. Kristjansson, Steven M. Kogan, Michael J. Mann, Megan L. Smith, Christa L. Lilly, Jack E. James

Public Health and Population Science Faculty Publications and Presentations

Background

Preventing nicotine use onset among children and youth is an important public health goal. One possible contributor that has received little empirical investigation is caffeine use. The goal of this study was to examine the possible contribution of caffeine to nicotine onset during early adolescence.

Methods

We used data from the Young Mountaineer Health Study Cohort. Survey data were collected from 1,349 (response rate: 80.7%) 6^th grade students (mean age at baseline 11.5 years) in 20 middle schools in West Virginia during the fall of 2020 and spring of 2021. We limited our analyses to students reporting never …

Efficacy Of Information Extraction From Bar, Line, Circular, Bubble And Radar Graphs, Hiddadura Isura Malinda Mendis Abeynayake, Ravindra S. Goonetilleke, Albert Wijeweera, Uwe Reischl

Public Health and Population Science Faculty Publications and Presentations

With the emergence of enormous amounts of data, numerous ways to visualize such data have been used. Bar, circular, line, radar and bubble graphs that are ubiquitous were investigated for their effectiveness. Fourteen participants performed four types of evaluations: between categories (cities), within categories (transport modes within a city), all categories, and a direct reading within a category from a graph. The representations were presented in random order and participants were asked to respond to sixteen questions to the best of their ability after visually scanning the related graph. There were two trials on two separate days for each participant. …

Social Support And Perceptions Of Covid-19-Related Emotional Impact On Mental Health Among Early Adolescents In Appalachia, Hannah M. Layman, Michael J. Mann, Megan L. Smith, Steven M. Kogan, Alfgeir L. Kristjansson

Public Health and Population Science Faculty Publications and Presentations

Background: Young people who experience higher levels of social support from their schools and families have been shown to be less likely to develop symptoms of negative mental health outcomes such as depression and anxiety.1–4 This raises questions concerning how young people's stress and psychological changes due to the COVID-19 pandemic as well as social support during this time have affected their overall mental health. The aim of this study was to assess the association between sources of parental- and school-level social support and youth perceptions of COVID-19-related emotional impact on mental health among early adolescent girls and boys in …

Is Adiposity Related To Repeat Measures Of Blood Leukocyte Dna Methylation Across Childhood And Adolescence?, Luke Montrose

Public Health and Population Science Faculty Publications and Presentations

Epigenetic modifications such as DNA methylation may influence gene expression and phenotypes, including obesity in childhood. The directionality of this relationship is nevertheless unclear, and some evidence suggests that adiposity modifies the epigenome, rather than the other way around. In this pilot study, we utilize data from the Early Life Exposures in Mexico to Environmental Toxicants (ELEMENT) study to examine whether measures of adiposity in childhood and early adolescence are associated with repeated measures of blood leukocyte DNA methylation at LINE-1 repetitive elements and two genes implicated in growth and adiposity: H19 and HSD11B2. Longitudinal epigenetic data were generated …

Sustaining Rural Pharmacy Workforce Understanding Key Attributes For Enhanced Retention And Recruitment, Daniel Terry, Blake Peck, Danny Hills, Jaclyn Bishop, Mark Kirschbaum, Kehinde Obamiro, Hoang Phan, Ed Baker, David Schmitz

Public Health and Population Science Faculty Publications and Presentations

Objective: To pilot the Pharmacist Community Apgar Questionnaire (PharmCAQ) and evaluate its usability and capacity to develop a greater understanding of the unique factors that impact the rural recruitment and retention of pharmacists.

Design: Cross-sectional design involving face-to-face, telephone or video conferencing interviews.

Setting: Twelve rural communities across Tasmania and Western Victoria, Australia.

Participants: Participants (n = 24) included pharmacists, a Director of Clinical Services, pharmacy practice managers and senior pharmacy assistants.

Main Outcome Measures: Interviews enabled the completion of the PharmCAQ, which assigns quantitative values to 50 key factors to ascertain a community's strengths and challenges associated with …

Simplifying Blood Pressure Measurements In Clinical Settings, Uwe Reischl, Conrad Colby

Public Health and Population Science Faculty Publications and Presentations

Background: Upper arm sphygmomanometry is the most commonly used method to measure blood pressure in adults. However, variations in upper arm circumference and use of different cuff-sizes results in different pressure readings. When using the same cuff size, pressure readings will be higher for larger arm circumferences and lower for smaller arm circumferences. The objective of this study was to identify an adjustment factor that will allow pressure readings obtained for any combination of arm circumference and cuff size to be compared.

Methods: To investigate the relationship between arm circumferences, cuff size and pressure readings, experiments were conducted using laboratory …

Screening The “Invisible Population” Of Older Adult Patients For Prescription Pain Reliever Non-Medical Use And Use Disorders, Alyssa M. Falise, Vinita Sharma, Carolin C. Hoeflich, Catalina Lopez-Quintero, Catherine W. Striley

Public Health and Population Science Faculty Publications and Presentations

Background: In the United States, the number of older adults reporting non-medical use of prescription pain relievers (NMUPPR) between 2015 and 2019 has remained constant, while those meeting criteria for opioid use disorders (OUDs) between 2013 and 2018 increased three-fold. These rates are expected to increase due to increased life expectancy among this population coupled with higher rates of substance use. However, they have consistently lower screening rates for problematic prescription pain reliever use, compared to younger cohorts. Objectives: This commentary reviewed trends in older adult NMUPPR and OUDs and reviewed several available screening tools. We then considered …

Perspective: Organic Food Consumption During Pregnancy And The Potential Effects On Maternal And Offspring Health, Cynthia L. Curl, Annica Balentine

Public Health and Population Science Faculty Publications and Presentations

Pregnancy represents a critical window for both maternal and child health. Previous studies have shown that the consumption of an organic diet during pregnancy can reduce pesticide exposure compared with the consumption of a conventional diet. It is possible that this could, in turn, improve pregnancy outcomes, because maternal pesticide exposure during pregnancy has been associated with increased risk of pregnancy complications. Organic foods are produced by methods that comply with organic standards, generally restricting the use of agrochemicals, such as synthetic pesticides. In the past few decades, the global demand for organic foods has increased drastically, driven in large …

The Opportunity Cost Of Covid For Public Health Practice: Covid-19 Pandemic Response Work And Lost Foundational Areas Of Public Health Work, J. Mac Mccullough, Moriah Robins

Public Health and Population Science Faculty Publications and Presentations

Context: There is little empirical evidence regarding the magnitude of the COVID-19 response across the public health workforce and the extent to which other public health programs were called upon to contribute to the response, potentially leading to less work being done in other public health programs during the COVID-19 pandemic.

Objectives: To assess the composition of the workforce that contributed to the COVID-19 pandemic response during 2020-2022.

Design: A large, cross-sectional, nationally representative survey of the state and local public health agency workforce through the Public Health Workforce Interest and Needs Survey (PH WINS).

Setting: Nearly all state health …