Medicine and Health Sciences Commons^™

Characterizing The Development Of Episodic Memory And Assessing The Reliability Of Fmri Measures, Lingfei Tang

Wayne State University Dissertations

The ability to remember past events is critical for everyday life and showed robust improvement over development from childhood to adulthood. With advances in noninvasive neuroimaging methods such as functional MRI in recent years, research efforts have been focused on identifying neural correlates underpinning developmental gains in memory performance. In my dissertation work, using a widely-validated subsequent memory paradigm, I aim to characterize functional MRI correlates of memory development. Specifically, I focused my investigation on identifying age differences in the functional patterns of two brain regions critical for memory, the prefrontal cortex and the hippocampus. Focusing on the prefrontal cortex …

The Semantic Memory Imaging In Late Life Pilot Study, Michael Adam Sugarman

Wayne State University Dissertations

Introduction: Several functional magnetic resonance imaging (fMRI) studies have analyzed the famous name discrimination task (FNDT), an uncontrolled semantic memory probe requiring discrimination between famous and unfamiliar individuals. Completion of this simple task recruits a semantic memory network that has shown utility in determining risk for Alzheimer's disease (AD). Specific semantic memory probes using biographical information associated with famous individuals may build on previous findings and yield superior information regarding risk for AD.

Method: Sixteen cognitively intact elders completed the FNDT and two novel tasks during fMRI: Categories (matching famous individuals to occupational categories) and Attributes (matching famous individuals to …

Fear Of Alzheimer's Disease And Its Role In Memory Monitoring And Control, Annalise Marie Rahman

Wayne State University Dissertations

Introduction: Fear of Alzheimer’s disease (FAD), or Anticipatory Dementia, is a healthy adult’s misinterpretation of everyday memory failures as indicators of developing dementia. The current study investigated the construct of FAD and aimed to contextualize FAD within the Health Belief Model through development of a new scale, the Anticipatory Dementia Index (ADI). The study also assessed the relationship between FAD and metacognitive monitoring and metacognitive control.

Methods: 94 cognitively-intact community-dwelling older adults with and without a history of family history of AD completed questionnaires regarding their subjective memory complaints, state and trait anxiety, depression, and multiple measures of FAD, including …

Neural Correlates Of Episodic Memory Formation In Children And Adults, Lingfei Tang

Wayne State University Theses

The medial temporal lobe (MTL) and prefrontal cortex (PFC) are two key brain regions that support episodic memory formation in both children and adults, but the functional developmental of these regions remains unclear. In this study, we investigated the development of neural correlates of episodic memory formation using functional MRI with a subsequent memory paradigm, administered to a cross-sectional sample of 83 children and adults. We found that MTL subregions showed an age-related increase in activation supporting memory formation of complex scenes. In addition, a functionally defined scene-sensitive region in the posterior MTL also showed similar increase and predicted better …

Longitudinal Change In Regional Cortices And Fluid Intelligence, Peng Yuan

Wayne State University Dissertations

Fluid intelligence (Gf) and crystalized intelligence (Gc) are two factors of the general intelligence. They have distinct age-related trajectories of change. Jung and Haier proposed Parieto-Frontal Integration Theory (P-FIT, 2007) to account for the inter-person variance in reasoning intelligence. Some brain regions such as prefrontal, parietal, temporal and anterior cingulate cortices were included in the P-FIT model and were hypothesized to be involved in fluid reasoning task. Therefore, in the current study, we examined latent growth curves (LGC) of longitudinal change in Gf, Gc, prefrontal cortex, parietal cortex, anterior cingulate, temporal cortex and primary visual cortex. Forty-six healthy middle-aged and …

Accumulation Of Subcortical Iron As A Modifier Of Volumetric And Cognitive Decline In Healthy Aging: Two Longitudinal Studies, Ana Marie Daugherty

Wayne State University Dissertations

Accumulation of non-heme iron in the brain has been theorized as a cellular mechanism underlying global neural and cognitive decline in normal aging and neurodegenerative disease. Relatively few studies of brain iron in normal aging exist and extant studies are almost exclusively cross-sectional. Here, I estimated iron content via T2* and measured volumes in several brain regions in two independent samples of healthy adults. The first sample (N = 89) was measured twice with a two-year delay; and the second sample (N = 32) was assessed four times over a span of 7 years. Latent models estimated change in iron …

White Matter Integrity And Age Related Differences In Reaction Time Components, Yiqin Yang

Wayne State University Dissertations

Reduced speed in information processing is a well-documented phenomenon associated with advanced aging. Age-related deterioration in white matter integrity might play a role in age-related increase in reaction time (RT). However, the association between microstructural differences in particular white matter regions or tracts with RT is unclear. Decomposing RT into parts might be a better way to understand the relationship due to multiple processes involved in RT. In a lifespan sample of 90 healthy normotensive participants, this study examined the association between RT components derived from the Ratcliff diffusion model with age related difference in DTI indices of a wide …

Functional Correlates Of Verbal Working Memory In Healthy Aging And Early Alzheimer's Disease, Michael Adam Sugarman

Wayne State University Theses

Deficits in the working memory system are common in patients diagnosed with Alzheimer's disease (AD). However, little is known regarding the neurobiological basis of this impairment. The current study examined the neurobiological functional correlates of the working memory system in early AD patients and cognitively intact control participants using a word list repetition task performed during positron emission tomography (PET). Compared to a reading control task, both the AD and control groups utilized a network of parietal, frontal, and cerebellar regions while completing the word rehearsal task. However, control participants displayed greater activation in all regions, especially in the parietal …

Psychosocial Aspects Of Physical Activity And Fitness In Special-Population, Minority Middle School Children, Jeffrey J. Martin, Nate Mccaughtry, Anne S. Murphy, Sara Flory, Kimberlydawn Wisdom

Kinesiology, Health and Sport Studies

Special-population research predicting physical activity (PA) and fitness with minority middle school children from at-risk environments is rare. Hence, the purpose of our investigation was to evaluate the ability of important social cognitive and environment-based measures to predict PA and fitness with children with developmental delay, cognitive, and emotional impairments. Children (N = 89, ages 11-15) completed questionnaires assessing social cognitive and environment-based constructs, self report PA, and completed fitness testing. Correlational results supported some hypotheses. The descriptive and correlational results also indicated commonalities with similar research on non special-population minority middle school children from at-risk environments.

Communicative Competence In Persons With Aphasia: The Impact Of Executive Function, Judy Marie Mikola

Wayne State University Dissertations

The purpose of this study was to examine the relationship between executive function and performance on selected linguistic tasks in persons with aphasia secondary to left frontal lesions.

A group of 15 persons with aphasia (PWA) completed three communication board tasks of varying levels of complexity and structure. The subject's functional use of the picture/word communication board was tested during a Story Retelling task. In addition, the PWA's executive function skills were examined using six nonverbal tests. The PWA group performance scores were compared to that of the neurologically healthy control group.

Results demonstrated that the control group performed significantly …

Using Social Cognitive Theory To Predict Physical Activity In Inner-City African American School Children, Jeffrey J. Martin, Nate Mccaughtry

Kinesiology, Health and Sport Studies

Researchers using social cognitive theory and employing built environment constructs to predict physical activity (PA) in inner-city African American children is quite limited. Thus, the purpose of our investigation was to evaluate the ability of important social cognitive variables (e.g., self-efficacy) and built environment constructs (e.g., neighborhood hazards) to predict African American children’s PA. Children (N = 331, ages 10–14) completed questionnaires assessing social cognitive theory constructs and PA. Using multiple regression analyses we were able to account for 19% of the variance in PA. Based on standardized beta weights, the best predictors of PA were time spent outside …

Multidimensional Self-Efficacy And Affect In Wheelchair Basketball Players, Jeffrey J. Martin

Kinesiology, Health and Sport Studies

In the current study, variables grounded in social cognitive theory with athletes with disabilities were examined. Performance, training, resiliency, and thought control self-efficacy, and positive (PA) and negative (NA) affect were examined with wheelchair basketball athletes (N = 79). Consistent with social cognitive theory, weak to strong significant relationships among the four types of self-efficacy (rs = .22–.78) and among self-efficacy and affect (rs = -.40–.29) were found. Basketball players who were efficacious in their ability to overcome training barriers were also confident in their basketball skills and efficacious in their ability to overcome ruminating distressing thoughts …

Predicting Physical Activity In Arab American School Children, Jeffrey J. Martin, Nate Mccaughtry, Bo Shen

Kinesiology, Health and Sport Studies

Theoretically grounded research on the determinants of Arab American children's physical activity is virtually nonexistent. Thus, the purpose of our investigation was to evaluate the ability of the theory of planned behavior (TPB) and social cognitive theory (SCT) to predict Arab American children's moderate-to-vigorous physical activity (MVPA). Children (N = 348, ages 10–14) completed questionnaires assessing the TPB and SCT constructs as well as MVPA. Using multiple regression analyses we were able to account for 9% of the variance in MVPA. Based on standardized beta-weights, variance accounted for, and the significance of F change, we concluded that SCT variables …

The Theory Of Planned Behavior: Predicting Physical Activity In Mexican American Children, Jeffrey J. Martin, Kimberly L. Oliver, Nate Mccaughtry

Kinesiology, Health and Sport Studies

Theoretically grounded research on the determinants of Mexican American children's physical activity and related psychosocial variables is scarce. Thus, the purpose of our investigation was to evaluate the ability of the theory of planned behavior (TPB) to predict Mexican American children's self-reported moderate-to-vigorous physical activity (MVPA). Children (N = 475, ages 9–12) completed questionnaires assessing the TPB constructs and MVPA. Multiple regression analyses provided moderate support for the ability of the TPB variables to predict MVPA as we accounted for between 8–9% of the variance in MVPA. Attitude, subjective norm, and perceived behavioral control accounted for 45% of the …

A Social Cognitive Perspective Of Physical-Activity-Related Behavior In Physical Education, Jeffrey J. Martin, Pamela Hodges Kulinna

Kinesiology, Health and Sport Studies

The purpose of the current study was to examine student and teacher physical-activity-related behavior using the theory of planned behavior and self-efficacy theory. Although teachers reported an overwhelmingly positive attitude toward teaching physical activity lessons to promote fitness development, they only devoted 4% of their class time to actually demonstrating and promoting fitness. Students were quite sedentary during class spending 61% of class time sitting, standing, or lying down. Using hierarchical regression analyses, teachers' attitudes toward teaching physically active physical education classes accounted for 50% of the variance in teachers' intention. Teachers who demonstrated/promoted fitness and who limited their general …

The Development Of A Physical Education Teachers' Physical Activity Self-Efficacy Instrument, Jeffrey J. Martin, Pamela Hodges Kulinna

Kinesiology, Health and Sport Studies

In the present investigation a questionnaire was developed to assess physical education teachers' self-efficacy for teaching classes in which their students were engaged in high levels of physical activity (i.e., at least 50% of class time). Exploratory and confirmatory factor analyses resulted in the development of a 16-item, 4-factor, multidimensional physical education teachers' physical activity self-efficacy scale (PETPAS) that produced reliable and valid scores. The Student factor reflected teachers' efficacy for managing students who didn't enjoy or value physical activity. The Time factor was indicative of teachers' efficacy when they didn't have enough time to teach. The Space factor reflected …

Training And Performance Self-Efficacy, Affect, And Performance In Wheelchair Road Racers, Jeffrey J. Martin

Kinesiology, Health and Sport Studies

In the current study, social cognitive theory was examined with athletes with disabilities. More specifically, hierarchical and self-regulatory performance self-efficacy, self-regulatory training self-efficacy, outcome confidence, and affect were examined with wheelchair road racers (N = 51). In accordance with social cognitive theory, moderate to strong significant relationships among 3 types of self-efficacy and outcome confidence were found (rs = .41 - .78). All forms of self-efficacy and positive affect (rs = .39 - .56) were also related providing additional support to social cognitive theory and the important relationships among training and performance related efficacy and affect in …

Factor Structure Of The Athletic Identity Measurement Scale With Athletes With Disabilities, Jeffrey J. Martin, Robert C. Eklund, Carol Adams Mushett

Kinesiology, Health and Sport Studies

Individuals who perceive themselves as "athletes" are thought to have self-schemas composed of, in part, an athletic identity (Brewer, Van Raalte, & Linder, 1993). The recent development of the Athletic Identity Measurement Scale (AIMS) has allowed sport psychology researchers to assess athletic identity. Research with adolescent athletes with disabilities has suggested that the AIMS is composed of 4 factors (Martin, Mushett, & Eklund, 1994). The purpose of the current study was to further examine the psychometric properties of the AIMS. Seventy-eight international swimmers (34 females, 44 males) with disabilities, ranging in age from 12 to 44 (M = 23.4 …

The Relationships Among Competitiveness, Age And Ability In Distance Runners, Robert C. Eklund, Jeffrey J. Martin, Alan L. Smith

Kinesiology, Health and Sport Studies

The purpose of this study was to examine relationships suggested by general achievement motivation literature and the popular literature in sport using the Sport Orientation Questionnaire (SOQ). The current study examined if faster runners are more competitive than slower runners, if older athletes were less competitive than younger athletes, and if faster runners were more goal oriented than slower runners. Distance runners (n=80), ranging from 10 to 61 years old completed race packets containing a cover letter, consent forms, the SOQ and a demographic questionnaire. Runners averaged 32.9 years of age and reported levels of competitiveness and goal …