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Full-Text Articles in Medicine and Health Sciences
Artificial Sweeteners And Weight Gain: Fighting Or Feeding The Obesity Epidemic?, Shanna Frisch
Artificial Sweeteners And Weight Gain: Fighting Or Feeding The Obesity Epidemic?, Shanna Frisch
The Science Journal of the Lander College of Arts and Sciences
Our world has developed an obsession with weight control and, as a result, has begun replacing high calorie foods with low-fat and non-caloric substitutes. Artificial sweeteners are a widely used solution to this growing problem. Though the intention when using artificial sweeteners is to lose weight, studies have shown that the opposite sometimes occurs. Researchers attempt to explain this surprising phenomenon with multiple hypotheses. Lack of appetite suppression and reward response may cause individuals to search for more food and to consume more calories. Artificial sweeteners can also have negative affects on biological mechanisms such as resting metabolic rate, as …
Regulation Of Ghrelin: A Possible Treatment Option For Obesity And Diabetes, Sarah Picciotto
Regulation Of Ghrelin: A Possible Treatment Option For Obesity And Diabetes, Sarah Picciotto
The Science Journal of the Lander College of Arts and Sciences
Obesity is a mounting problem in America today. One major concern about obesity is that it is a risk factor for type 2 diabetes, a disease that impairs insulin sensitivity and secretion. This interferes with blood glucose levels and can cause hyperglycemia, which is when there is too much circulating glucose in the blood. Ghrelin, an amino acid peptide responsible for appetite stimulation and energy balance, plays a direct role in insulin secretion and glucose metabolism. In many experiments, elevated ghrelin levels are associated with decreased insulin secretion from pancreatic islet cells. Although ghrelin concentration is decreased in obese individuals …
The Role Of Ghrelin And Leptin In Obesity: Is Exogenous Administration Of These Hormones A Possible Drug Therapy?, Peri Eckstein
The Role Of Ghrelin And Leptin In Obesity: Is Exogenous Administration Of These Hormones A Possible Drug Therapy?, Peri Eckstein
The Science Journal of the Lander College of Arts and Sciences
Ghrelin and leptin are two hormones that have been recognized to have a major influence on energy balance. Leptin is a mediator of long term regulation of energy balance, suppressing food intake and thereby inducing weight loss. Ghrelin, on the other hand, is a fast acting hormone, playing a role in meal initiation. As a growing number of people suffer from obesity, understanding the mechanisms by which various hormones and neurotransmitters influence energy balance has been a subject of intense research. This paper provides background on leptin and ghrelin hormones, their role in food intake and body weight in humans, …