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Full-Text Articles in Medicine and Health Sciences
The Benefits Of Astaxanthin To Improve Pain Relief In Patients With Painful Diabetic Neuropathy: An Open-Label, Randomized Controlled Trial, Rizaldy Taslim Pinzon, Mary Rose Angelina Budi Harsana
The Benefits Of Astaxanthin To Improve Pain Relief In Patients With Painful Diabetic Neuropathy: An Open-Label, Randomized Controlled Trial, Rizaldy Taslim Pinzon, Mary Rose Angelina Budi Harsana
Pharmaceutical Sciences and Research
Treatment of diabetic neuropathy is still carried out by providing symptomatic therapy, which only improves ± 50% of the total symptoms felt by patients, but does not tackle the underlying causes of the disease. Astaxanthin is a potent antioxidant, anti-inflammatory, and anti-diabetic carotenoid that could be an additional treatment option. We aimed to measure the effectiveness of administering astaxanthin as an additional therapy to improve the impact of pain and discomfort experienced daily by diabetes mellitus patients with painful diabetic neuropathy. We conducted a randomized experimental study with an open label design of 36 patients who had been diagnosed with …
The Antioxidant And Antimicrobial Activities Of Cornsilk Extract Encapsulated In Polysaccharide Nanoparticles, Maryam Mady
The Antioxidant And Antimicrobial Activities Of Cornsilk Extract Encapsulated In Polysaccharide Nanoparticles, Maryam Mady
Theses and Dissertations
Corn silk possess antibacterial and antioxidant activities due to its phenolic compounds but they are of low bioavailability that requires some innovative techniques to develop such active ingredients in a safe and less toxic manner. Accordingly, silk extract SE was encapsulated in chitosan nanoparticles CS NPs, which is a natural and abundant polymer derived from chitin. Among 15 experimental trials via design expert software, the optimum formula of SE x\CS NPs was prepared at 800 rpm, 5hrs. on magnetic stirrer, and by CS: TPP ratio was 2.5:1. Then SEM showed the majority of particles size diameter in the range of …
New Dithiocarbamates As A Possible Human Serum Albumin Metal Carrier In Drug Delivery Systems And Their Antioxidant And Antiproliferative Activities, Saadi M.D. Al-Nuzal, Azhar M. Haleem, Ken Czerwinski, Salah M. Haleem
New Dithiocarbamates As A Possible Human Serum Albumin Metal Carrier In Drug Delivery Systems And Their Antioxidant And Antiproliferative Activities, Saadi M.D. Al-Nuzal, Azhar M. Haleem, Ken Czerwinski, Salah M. Haleem
Chemistry and Biochemistry Faculty Research
New mono- and bis-dithiocarbamates were prepared from the reaction of organic dihydrazides -NHNH-(C=O)(CH2)x-(C=O)NHNH- (where x = 0, 2, 4) and basic carbon disulfide with varying chain length 10-14 atom as a human serum metal carrier. The products were characterized by various spectrophotometric such as 1H and 13C NMR and elemental analysis. Their antiproliferative activities were examined on two species of the standard strains of the Gram-positive Staphylococcus aureus ATCC 25923 and Gram-negative Escherichia coli ATCC 25922 by following the procedure of broth micro-dilution method (BMM), which was applied at the concentrations: 0.0, 100, 200, and 300 ppm for each compound. …