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Articles 1 - 7 of 7
Full-Text Articles in Medicine and Health Sciences
Synthesis And Biological Study Of Adenylyl Cyclase Inhibitors, Siyuan Sun, Zhishi Ye, Mingji Dai
Synthesis And Biological Study Of Adenylyl Cyclase Inhibitors, Siyuan Sun, Zhishi Ye, Mingji Dai
The Summer Undergraduate Research Fellowship (SURF) Symposium
Adenylyl cyclases (AC) is a critical family of enzymes which modulates the dynamic cellular level of cAMP, cyclic adenosine monophosphate. The study of cAMP showed that it is indispensable for the signal transduction cascades during many physiological processes, such as immune responses and metabolism which highly relate to cancers. Previous studies of AC inhibitors have been limited due to a lack of isoform-selective small molecule modulators. Selectivity of the molecules is imperative to the activation of only the desired AC inhibitor. The design of the described project was to test the structure activity relationship (SAR) by synthesizing a class of …
Tissue Engineering: Applications In Developmental Toxicology, Stephanie N. Thiede, Nimisha Bajaj, Kevin Buno, Sherry L. Voytik-Harbin
Tissue Engineering: Applications In Developmental Toxicology, Stephanie N. Thiede, Nimisha Bajaj, Kevin Buno, Sherry L. Voytik-Harbin
The Summer Undergraduate Research Fellowship (SURF) Symposium
In vivo toxicology assays are expensive, low-throughput, and often not predictive of a human response. Three-dimensional in vitro human cell-based tissue systems incorporating cell-cell and cell-matrix interactions have promise to provide high-throughput, physiologically-relevant information on the mechanism of the toxin and a more accurate assessment of the toxicity of a chemical before progression to human trials. Quantification of the disruption of vasculogenesis, the de novo formation of blood vessels from endothelial progenitor cells, can serve as an appropriate indicator of developmental toxicity since vasculogenesis is critical to the early development of the circulatory system. The current routinely used in vitro …
Control Of Inflammation In Pancreatic Β-Cells: Role Of Arylpyrazole Compounds, Whitney Lyn Powell
Control Of Inflammation In Pancreatic Β-Cells: Role Of Arylpyrazole Compounds, Whitney Lyn Powell
EURēCA: Exhibition of Undergraduate Research and Creative Achievement
No abstract provided.
The Isolation Of A Red Pigment, Having Industrial And Medicinal Potential, Philip Strate
The Isolation Of A Red Pigment, Having Industrial And Medicinal Potential, Philip Strate
Georgia State Undergraduate Research Conference
No abstract provided.
Mamba Juice: Expression Of Exogenous Mambalgin Peptide Using The Pgapzα Vector System, Lydia Studdard, Kristin Vanmouwerik, Merhawi Yigzaw, Reza Alavi
Mamba Juice: Expression Of Exogenous Mambalgin Peptide Using The Pgapzα Vector System, Lydia Studdard, Kristin Vanmouwerik, Merhawi Yigzaw, Reza Alavi
Georgia State Undergraduate Research Conference
No abstract provided.
Development Of A Safe And Efficient Near-Infrared Diagnostic Method For Alzheimer's Disease, Joseph Tawney
Development Of A Safe And Efficient Near-Infrared Diagnostic Method For Alzheimer's Disease, Joseph Tawney
Georgia State Undergraduate Research Conference
No abstract provided.
The Effects Of Picrotoxin And Ethanol On Crayfish Escape And Central Motor Pattern Neural Circuits, Rebecca Bierman, Nathan Hardcastle, Colin Istvan
The Effects Of Picrotoxin And Ethanol On Crayfish Escape And Central Motor Pattern Neural Circuits, Rebecca Bierman, Nathan Hardcastle, Colin Istvan
Georgia State Undergraduate Research Conference
No abstract provided.