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Full-Text Articles in Medicine and Health Sciences

Detection And Extraction Of Pfoa And Pfos Via Mips, Joseph Redding May 2024

Detection And Extraction Of Pfoa And Pfos Via Mips, Joseph Redding

Senior Honors Theses

Perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) are utilized as surfactants in many different materials. With an immensely stable structure due to the presence of carbon-fluorine bonds, PFOA and PFOS are resistant to degradation. Known to persist in water resources, these compounds tend to bioaccumulate and impute toxic effects on human health, such as decreased fertility and immune function. To date, there exists no effective approach to the removal of these lingering compounds. Because of the health risks, there is increasing urgency to devise a means by which to detect and withdraw PFOA and PFOS from the environment. In …


The Purification And Thermal Stability Of The Peroxidase Enzyme In Cucurbita Moschata, Garen Hamner Apr 2024

The Purification And Thermal Stability Of The Peroxidase Enzyme In Cucurbita Moschata, Garen Hamner

Senior Honors Theses

Peroxidases are enzymes that catalyze the reduction of hydrogen peroxide to water while oxidizing organic substrates and are valuable in spheres like industrial and medical applications and histochemistry. Limitations still exist in the use of the well-studied horseradish peroxidase for certain activities due to limitations like poor thermal stability, thus the search for novel peroxidases that can overcome these limitations is an active area of research. Butternut squash peroxidase (Cucurbita moschata) (BSP) shows promise due to significant activity being found in the skin and apparent enhanced thermal stability, but an efficient purification scheme for it is lacking, as well as …