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Full-Text Articles in Medicine and Health Sciences
The Effect Of Cannabinoids On Triple Negative Breast Cancer Cells, Haley Dahl
The Effect Of Cannabinoids On Triple Negative Breast Cancer Cells, Haley Dahl
Honors Theses
Triple Negative Breast Cancer (TNBC) is a difficult type of cancer to treat because it is negative for progesterone, estrogen, and HER-2 receptors. Because TNBC is negative for these three receptors, it does not respond to normal hormonal therapies. The purpose of my experiment is to see if different cannabinoids, compounds from the cannabis plants, could be used as alternative treatment options. These experiments employed three different cannabinoids: ajulemic acid, cannabidiol, and hemp oil. Cell viability was measured after 72 hours of treatment using a MTT assay. The results showed that the three cannabinoids could be used to effectively destroy …
Ten Weeks With Green Beans...And Then Some: Determination Of Bisphenol-A (Bpa) In Canned Goods From Arkansas Markets Using Fluorescence Spectrophotometry, Rachel Pruett
Honors Theses
Bisphenol A (BPA) is a chemical widely used in production of consumer goods. It has come under scrutiny recently after being labeled as an endocrine disruptor (ED), mostly causing adverse effects in infants and young children. It has been associated with diabetes, cardiovascular disease, and abnormal maturation. Because it is so commonly used in product development, humans are exposed to BPA through various means, such as ingestion or dermal absorption. It is a concern that the combined exposure could cause serious effects even in small doses.
In canned foods, the chemical is made into an epoxy resin to provide a …
Thrilling Monotony: A Summer Of Alzheimer's Research, Baronger Dowell Bieger
Thrilling Monotony: A Summer Of Alzheimer's Research, Baronger Dowell Bieger
Honors Theses
The primary genetic risk determinant for late-onset Alzheimer's disease is the apolipoprotein E gene (APOE). Variations in this gene produce three different isoforms of the apolipoprotein E protein (ApoE): ApoE2, ApoE3, and ApoE4. ApoE# is the most common isoform, so rates of LOAD among other genotypes are indexed to this variant. ApoE2 is rather rare, but its carriers are less likely to get LOAD; when they do, they get it later. The second most common variant is ApoE4, and its carriers are significantly more likely to get LOAD. They also tend to succumb earlier. Once developed, LOAD is characterized by …