Open Access. Powered by Scholars. Published by Universities.®

Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 2 of 2

Full-Text Articles in Medicine and Health Sciences

Preserving Ancient Cultures Through Medicinal Narratives, Mckenzie Jewel Moss Dec 2019

Preserving Ancient Cultures Through Medicinal Narratives, Mckenzie Jewel Moss

Honors Projects

“Preserving Ancient Cultures through Medicinal Narratives” is a comprehensive project that takes an interdisciplinary approach to understanding the effects that culture has on health. The project as a whole includes the initial work and readings I performed to better understand differences in healing between the cultures found throughout South America, where Inca culture is still prevalent, and that of the Unites States, as well as an independent documentary. The documentary contains my own personal commentary complemented by video clips of interviews I performed with individuals living in South America.


The Infuence Of The Host Microbiome On 3,4- Methylenedioxymethamphetamine (Mdma)-Induced Hyperthermia And Vice Versa, Emily A. Ridge, Sudhan Pachhain, Sayantan Roy Choudhury, Sara R. Bodnar, Ray A. Larsen, Vipapom Phuntumart, Jon E. Sprague Mar 2019

The Infuence Of The Host Microbiome On 3,4- Methylenedioxymethamphetamine (Mdma)-Induced Hyperthermia And Vice Versa, Emily A. Ridge, Sudhan Pachhain, Sayantan Roy Choudhury, Sara R. Bodnar, Ray A. Larsen, Vipapom Phuntumart, Jon E. Sprague

Forensic Science Faculty Publications

Hyperthermia induced by 3,4-methylenedioxymethamphetamine (MDMA) can be life-threatening. Here, we investigate the role of the gut microbiome and TGR5 bile acid receptors in MDMA-mediated hyperthermia. Fourteen days prior to treatment with MDMA, male Sprague-Dawley rats were provided water or water treated with antibiotics. Animals that had received antibiotics displayed a reduction in gut bacteria and an attenuated hyperthermic response to MDMA. MDMA treated animals showed increased uncoupling protein 1 (UCP1)and TGR5 expression levels in brown adipose tissue and skeletal muscle while increased expression of UCP3 was observed only in skeletal muscle. Antibiotics prior to MDMA administration significantly blunted …