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Residential Traffic Exposure, Pulse Pressure, And C-Reactive Protein: Consistency And Contrast Among Exposure Characterization Methods, Christine L. Rioux, Katherine L. Tucker, Mkaya Mwamburi, David M. Gute, Steven A. Cohen, Doug Brugge

Katherine L. Tucker

Background: Traffic exposure may increase cardiovascular disease (CVD) risk via systemic inflammation and elevated blood pressure, two important clinical markers for managing disease progression. Objectives: We assessed degree and consistency of association between traffic exposure indicators as predictors of C-reactive protein (CRP) and pulse pressure (PP) in an adult U.S. Puerto Rican population (n = 1,017). Methods: Cross-sectional information on health and demographics and blood data was collected. Using multiple linear regression, we tested for associations between CRP, PP, and six traffic exposure indicators including residential proximity to roads with > 20,000 vehicles/day and traffic density [vehicle miles traveled per square …