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Full-Text Articles in Medicine and Health Sciences

Disseminated Varicella-Zoster Virus Infection Complicated By Encephalitis And Ramsay Hunt Syndrome In An Hiv Patient, Amro Elshereye, Burak Erdinc, Sonu Sahni Jul 2020

Disseminated Varicella-Zoster Virus Infection Complicated By Encephalitis And Ramsay Hunt Syndrome In An Hiv Patient, Amro Elshereye, Burak Erdinc, Sonu Sahni

Touro College of Osteopathic Medicine (New York) Publications and Research

Varicella-zoster virus (VZV) is a human α-herpesvirus which cause primary varicella infection (chicken pox) or herpes zoster infection (shingles) after reactivation of the dormant virus. VZV infection is usually self-limited but disseminated infection can be seen in immunocompromised individuals. It can also get complicated by central nervous system (CNS) involvement. We describe a case of a 51-year-old male with human immunodeficiency virus (HIV) who presented with altered mental status and deficits in his right-sided cranial nerves of VI, VII, and VIII. The patient also had disseminated vesicular-pustular rash all over his body at different stages of healing. A diagnosis of …


Multivessel Coronary Artery Fistula Presenting As Coronary Steal Syndrome Leading To Cardiac Arrest, Muhammad F Ahmed, Anaam Mubin, Rumman Syed, Abdullah K Mahmood, Sonu Sahni May 2020

Multivessel Coronary Artery Fistula Presenting As Coronary Steal Syndrome Leading To Cardiac Arrest, Muhammad F Ahmed, Anaam Mubin, Rumman Syed, Abdullah K Mahmood, Sonu Sahni

Touro College of Osteopathic Medicine (New York) Publications and Research

The coronary steal phenomenon refers to myocardial ischemia caused by the diversion of blood away from normal myocardial circulation. A coronary artery fistula (CAF) is an abnormality of the coronary anatomy characterized by the aberrant termination of a coronary artery or its branches into cardiac chambers or great vessels. Although CAFs are often thought to be asymptomatic, fistulas that diverge a significant amount of blood flow and decrease the normal perfusion of myocardial tissue can cause ischemia and can present with acute coronary syndrome. We describe a unique case of a 70-year-old woman with no coronary artery disease (CAD) undergoing …


Paraneoplastic Pemphigus: An Indication For Treatment In Chronic Lymphocytic Leukemia, Ifeanyichukwu Onukogu, Preethi Ramachandran, Joshua Narh, Sonu Sahni, Gardith Joseph May 2020

Paraneoplastic Pemphigus: An Indication For Treatment In Chronic Lymphocytic Leukemia, Ifeanyichukwu Onukogu, Preethi Ramachandran, Joshua Narh, Sonu Sahni, Gardith Joseph

Touro College of Osteopathic Medicine (New York) Publications and Research

Paraneoplastic disorders are rare multiorgan diseases associated with hematological malignancies such as chronic lymphocytic leukemia (CLL). Some of these paraneoplasms manifest as cutaneous lesions, appearing as a simple rash, ulcers or skin thickening. The pathogenesis for this process has been described as development of certain autoimmune reactions against cell wall antigens and proteins. An example is paraneoplastic pemphigus (PNP) which manifests as cutaneous bullae. Bullae may occur anytime during the course of the malignancy i.e. acute phase or remission. Diagnosis involves evaluation of clinical findings, serology and presence of characteristic histological findings. Its pathogenesis is described as development of auto-antibodies …


Giant Left Main Coronary Artery Aneurysm Presenting As Multiple Implantable Cardioverter Defibrillator Shocks, Yury Malyshev, Asma Syed, Ricardo Castillo, Rumman A Syed, Sonu Sahni Apr 2020

Giant Left Main Coronary Artery Aneurysm Presenting As Multiple Implantable Cardioverter Defibrillator Shocks, Yury Malyshev, Asma Syed, Ricardo Castillo, Rumman A Syed, Sonu Sahni

Touro College of Osteopathic Medicine (New York) Publications and Research

Giant aneurysms of the left main coronary artery are one of the rarest findings in cardiology, encountered in less than 0.02% of patients. The presentation is usually the same as coronary artery disease since most coronary aneurysms in the western world are associated with atherosclerosis. Here we report the first case of giant aneurysm of the left main coronary artery presenting as ventricular tachycardia with multiple shocks of the defibrillator in a 57-year-old man with heart failure. We also review the etiology, pathology, and management of coronary aneurysms.


Narrow Escape: A Novel Approach To The Endovascular Treatment Of Superior Vena Cava Syndrome Secondary To Pacemaker Leads With Excellent Long-Term Outcomes, Yury Malyshev, Sergey Ayzenberg, Sonu Sahni, Mazin Khalid, Jeffrey Le Mar 2020

Narrow Escape: A Novel Approach To The Endovascular Treatment Of Superior Vena Cava Syndrome Secondary To Pacemaker Leads With Excellent Long-Term Outcomes, Yury Malyshev, Sergey Ayzenberg, Sonu Sahni, Mazin Khalid, Jeffrey Le

Touro College of Osteopathic Medicine (New York) Publications and Research

Pacemaker or defibrillator placement is a common procedure done in more and more patients due to increased longevity and the prominence of cardiac disease. With more indications for cardiac implantable electrode devices, the devices themselves have evolved into more complex structures with more leads. The mechanical stress, risk of infection, and decreased blood flow through the superior vena cava (SVC) put patients at risk for SVC obstruction. Herein, we present a rare case of complete SVC obstruction secondary to fibrosis due to pacemaker leads which was treated with venoplasty and showed excellent long-term results. We also review the current literature …


A Broken Heart: Cardiac Arrest As The Initial Presentation Of Myasthenic Crisis, Alexander Andreev, Farhana Begum, Anjuli Singh, Sonu Sahni Feb 2020

A Broken Heart: Cardiac Arrest As The Initial Presentation Of Myasthenic Crisis, Alexander Andreev, Farhana Begum, Anjuli Singh, Sonu Sahni

Touro College of Osteopathic Medicine (New York) Publications and Research

Myasthenic crisis is a life-threatening condition commonly associated with respiratory failure and may present in unusual ways. However, there is paucity in the literature about the cardiac manifestations of myasthenia gravis. We present a case of a 61-year-old male who presented to the emergency room with upper respiratory infection symptoms who soon thereafter suffered sudden cardiac arrest. He was found to have shortened PR interval pre and post arrest onelectrocardiogram (EKG). Only past medical history, discovered post cardiac arrest, was myastenia gravis. All other causes of cardiac arrest were ruled out, and it was deemed to be due to a …


Wellens' Syndrome Presenting As Epigastric Pain And Syncope: An Unusual Presentation, Temitope Ajibawo, Alexander Andreev, Sonu Sahni Feb 2020

Wellens' Syndrome Presenting As Epigastric Pain And Syncope: An Unusual Presentation, Temitope Ajibawo, Alexander Andreev, Sonu Sahni

Touro College of Osteopathic Medicine (New York) Publications and Research

Wellens' syndrome, also regarded as left anterior descending coronary T-wave syndrome, is an electrocardiography (EKG) pattern that indicates critical proximal left anterior descending artery (LAD) stenosis. It is characterized by deeply inverted T-waves or biphasic T-waves in the anterior precordial chest leads in a patient with unstable angina. Patients typically present with symptoms consistent with acute coronary syndrome. We present a unique case of Wellens' syndrome with no angiographic findings of significant stenosis in the proximal LAD but with significant occlusion of the proximal circumflex artery and initial presentation with a chief complaint of epigastric pain and syncope. Physicians need …