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Full-Text Articles in Medicine and Health Sciences
Subject-Specific Musculoskeletal Modeling Of Hip Dysplasia Biomechanics, Ke Song
Subject-Specific Musculoskeletal Modeling Of Hip Dysplasia Biomechanics, Ke Song
McKelvey School of Engineering Theses & Dissertations
Developmental dysplasia of the hip (DDH) is characterized by abnormal bony anatomy, causes pain and functional limitations, and is a prominent risk factor for premature hip osteoarthritis. Although the pathology of DDH is believed to be mechanically-induced, little is known about how DDH anatomy alters hip biomechanics during activities of daily living, partly due to the difficulties with measuring hip muscle and joint forces. Musculoskeletal models (MSMs) are useful for dynamic simulations of joint mechanics, but the reliability of MSMs for DDH research is limited by an accurate model representation of the unique hip anatomy. To address such challenges, this …
Improved Orthopaedic Repairs Through Mechanically Optimized, Adhesive Biomaterials, Stephen Wheeler Linderman
Improved Orthopaedic Repairs Through Mechanically Optimized, Adhesive Biomaterials, Stephen Wheeler Linderman
McKelvey School of Engineering Theses & Dissertations
Despite countless surgical advances over the last several decades refining surgical approaches, repair techniques, and tools to treat tendon and tendon-to-bone injuries, we are still left with repair solutions that rely on fairly crude underlying mechanical principles. Musculoskeletal soft tissues have evolved to transfer high loads by optimizing stress distribution profiles across the tissue at each length scale. However, instead of mimicking these natural load transfer mechanisms, conventional suture approaches are limited by high load transfer across only a small number of anchor points within tissue. This leads to stress concentrations at anchor points that often cause repair failure as …