Medicine and Health Sciences Commons^™

Accelerometry-Based Analysis Of Postural Sway In Parkinson's Disease Patients With Levodopa-Induced Dyskinesia, Chandler Brock

UNO Student Research and Creative Activity Fair

Parkinson’s disease (PD) is a progressive neurodegenerative disorder, with patient numbers projected to double to 12 million in the next 20 years. Levodopa-induced dyskinesia (LID) is a major problem associated with the long-term use of levodopa for symptomatic treatment of PD. These involuntary movements can become disabling and may interfere with quality of life. Our prior research showed that PD w/ LID were less stable while standing (i.e., increased postural sway) and had a higher incidence of falls. The aim of this study is to determine if postural sway properties are altered by LID via decomposing the sway signal. We …

The Effects Of Demographics And Risk Factors On The Morphological Characteristics Of Human Femoropopliteal Arteries, Sayed Ahmadreza Razian, Majid Jadidi, Alexey Kamenskiy

UNO Student Research and Creative Activity Fair

Background: Disease of the lower extremity arteries (Peripheral Arterial Disease, PAD) is associated with high morbidity and mortality. During disease development, the arteries adapt by changing their diameter, wall thickness, and residual deformations, but the effects of demographics and risk factors on this process are not clear.

Methods: Superficial femoral arteries from 736 subjects (505 male, 231 female, 12 to 99 years old, average age 51±17.8 years) and the associated demographic and risk factor variables were used to construct machine learning (ML) regression models that predicted morphological characteristics (diameter, wall thickness, and longitudinal opening angle resulting from the …

Design And Development Of Software With A Graphical User Interface To Display And Convert Multiple Microscopic Histology Images, Sayed Ahmadreza Razian, Majid Jadidi, Alexey Kamenskiy

UNO Student Research and Creative Activity Fair

Histological images are widely used to assess the microscopic anatomy of biological tissues. Recent advancements in image analysis allow the identification of structural features on histological sections that can help advance medical device development, brain and cancer research, drug discovery, vascular mechanobiology, and many other fields. Histological slide scanners create images in SVS and TIFF formats that were designed to archive image blocks and high-resolution textual information. Because these formats were primarily intended for storage, they are often not compatible with conventional image analysis software and require conversion before they can be used in research. We have developed a user-friendly …

A Systematic Review: Long Range Correlations In Running Gait, Mr. Taylor Wilson

UNO Student Research and Creative Activity Fair

Long range correlations (LRCs) are apparent in human walking and running gait and are indicative of a healthy system. A systematic review (SR) was completed to determine the typical LRC patterns in running. 20 articles were included in the SR. LRCs in running gait tend to be similar to the LRCs in walking gait, with fatigue contributing to a negative effect on the LRCs.

This SR could have implications on training guidelines for coaches and physical therapy methods to increase the LRCs in running gait for healthier functioning. More research is needed to determine how LRCs depend on running surface …

How The Foot Modulates Its Mechanics During Uphill And Downhill Walking, Jeffrey M. Patterson, Kota Z. Takahashi

UNO Student Research and Creative Activity Fair

The foot's biomechanical role in walking on sloped surfaces is currently unclear. While previous biomechanics studies have examined the hip, knee, and ankle, the foot is oversimplified as a rigid-body segment. This oversimplification overshadows its complex structure and function. In this project, we use an innovative multi-segment foot model to explore how the foot adapts its mechanics to incline and decline walking. Preliminary results have revealed that the foot is capable of adapting its mechanical work profile to both incline and decline walking. Specifically, the foot can increase its positive work output (i.e., increased energy generation) during inclined walking to …

3d Prosthetics Effects On Standing Posture In Unilateral Upper Limb Deficient Children, Keaton Young

UNO Student Research and Creative Activity Fair

3D Prosthetics Effects on Standing Posture in Unilateral Upper Limb Deficient Children

Keaton Young

Department of Biomechanics, University of Nebraska at Omaha

Introduction

Upper Limb Reduction Deficiency (ULD) is a congenital disability that affects the upper limb, which the Center for Disease Control and Prevention estimates that nearly 1,500 babies are born with ULD in the United States yearly ^1,2. Prior research has focused on functional treatment of the upper limbs but has lacked observance of the effects that prosthetics and limb loss incur to the trunk. Therefore, the purpose of this study is to examine the acute effects …