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Full-Text Articles in Medicine and Health Sciences
Effect Of Adjuvant And Neoadjuvant Anti-Telomerase With Anthracycline Based Chemotherapy On Triple Negative Breast Cancer Cells, Luke T. Pardy
Effect Of Adjuvant And Neoadjuvant Anti-Telomerase With Anthracycline Based Chemotherapy On Triple Negative Breast Cancer Cells, Luke T. Pardy
Student Summer Scholars Manuscripts
Breast cancer is the second leading cause of cancer related death in women in the US. In addition, 20% of all breast cancer cases in the U.S. are from the subtype known as Triple-Negative Breast Cancer (TNBC), which is the most aggressive and invasive form of the disease. This type of breast cancer has the worst prognosis, a decreased survival rate, and no targeted therapy. Over the decades, interest in pre- (Neoadjuvant) and post- (Adjuvant) chemotherapy treatments, in the management of TNBC has increased. Therefore, we evaluated the Adjuvant and Neoadjuvant effects of anti-telomerases (BIBR 1532 and GV6) with anthracycline-based …
Evidence For Transfer Of Membranes From Mesenchymal Stem Cells To Hl-1 Cardiac Cells, Robert Boomsma, David Geenen
Evidence For Transfer Of Membranes From Mesenchymal Stem Cells To Hl-1 Cardiac Cells, Robert Boomsma, David Geenen
Funded Articles
This study examined the interaction of mouse bone marrow mesenchymal stem cells (MSC) with cardiac HL-1 cells during coculture by fluorescent dye labeling and then flow cytometry. MSC were layered onto confluent HL-1 cell cultures in a 1 : 4 ratio. MSC gained gap junction permeant calcein from HL-1 cells after 4 hours which was partially reduced by oleamide. After 20 hours, 99% MSC gained calcein, unaffected by oleamide. Double-labeling HL-1 cells with calcein and the membrane dye DiO resulted in transfer of both calcein and DiO to MSC. When HL-1 cells were labeled with calcein and MSC with DiO, …
Individual, Temporal, And Seasonal Variation In Sperm Concentration In Tree Swallows, Michael P. Lombardo, Armetris N. Forman, Matthew R. Czarnowski, Patrick A. Thorpe
Individual, Temporal, And Seasonal Variation In Sperm Concentration In Tree Swallows, Michael P. Lombardo, Armetris N. Forman, Matthew R. Czarnowski, Patrick A. Thorpe
Peer Reviewed Publications
We determined sperm concentrations in Tree Swallows (Tachycineta bicolor) by manually expressing semen samples from males during prelaying, egg-laying, incubation, and nestling periods. Sperm concentrations varied by orders of magnitude (0-109 sperm mL-1) among males. Sperm concentrations were highest during the incubation period and lowest during the prelaying period. None of the samples collected during the prelaying, egg-laying, and incubation periods were devoid of sperm. In contrast, 45% of samples collected during the nestling period lacked sperm. Sperm concentrations (1) did not vary over the course of the morning during prelaying, egg-laying, and incubation periods …
Communities Of Cloacal Bacteria In Tree Swallow Families, Michael P. Lombardo, Patrick A. Thorpe, R. Cichewicz, M. Henshaw, C. Millard, C. Steen, T. K. Zeller
Communities Of Cloacal Bacteria In Tree Swallow Families, Michael P. Lombardo, Patrick A. Thorpe, R. Cichewicz, M. Henshaw, C. Millard, C. Steen, T. K. Zeller
Peer Reviewed Publications
Our aim in this study was to survey the communities of bacteria found in the cloacae of adult and nestling Tree Swallows (Tachycineta bicolor), determine if there were familial patterns of prevalence, and determine if there were relationships between bacteria loads and nestling size when 12 days old and fledging success.
Age At Menarche: Accuracy Of Recall After Thirty-Nine Years, Albert Damon, Carl J. Bajema
Age At Menarche: Accuracy Of Recall After Thirty-Nine Years, Albert Damon, Carl J. Bajema
Peer Reviewed Publications
Among 143 women whose menarcheal age was documented during a longitudinal growth study, recall 39 years after the even gave the following results: menarche was recalled as 0.2 years after earlier than the actual date (p<0.05), the standard deviation of recalled age was 0.3 years larger (p<0.01), and the coefficient of correlation, r, between actual and recalled age was 0.60 +/- s.e. 0.05.