Medicine and Health Sciences Commons^™

Functional Connectivity In Brain Networks Underlying Cognitive Control In Chronic Cannabis Users, Ian H. Harding, Nadia Solowij, Ben J. Harrison, Michael Takagi, Valentina Lorenzetti, Dan I. Lubman, Marc L. Seal, Christos Pantelis, Murat Yucel

Faculty of Health and Behavioural Sciences - Papers (Archive)

The long-term effect of regular cannabis use on brain function underlying cognitive control remains equivocal. Cognitive control abilities are thought to have a major role in everyday functioning, and their dysfunction has been implicated in the maintenance of maladaptive drug-taking patterns. In this study, the Multi-Source Interference Task was employed alongside functional magnetic resonance imaging and psychophysiological interaction methods to investigate functional interactions between brain regions underlying cognitive control. Current cannabis users with a history of greater than 10 years of daily or near-daily cannabis smoking (n=21) were compared with age, gender, and IQ-matched non-using controls (n=21). No differences in …