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Accelerated Achilles Tendon Healing With Interleukin-1 Receptor Antagonist Protein In Rabbits, Marko Pecin, Mario Kreszinger, Snjezana Vukovic, Marija Lipar, Ozren Smolec, Berislav Radisic, Josip Kos
Accelerated Achilles Tendon Healing With Interleukin-1 Receptor Antagonist Protein In Rabbits, Marko Pecin, Mario Kreszinger, Snjezana Vukovic, Marija Lipar, Ozren Smolec, Berislav Radisic, Josip Kos
Turkish Journal of Veterinary & Animal Sciences
The current study describes the use of interleukin-1 receptor antagonist protein (IL-1Ra) as a possible strategy for optimizing tendon healing and repair by presenting histologically visible changes in rabbit Achilles tendon tissue after longitudinal tenotomy. The study was carried out on 26 Californian rabbits divided into two equal groups. One was the experimental IRAP (interleukin-1 receptor antagonist) group and the second one was the PBS (purified buffered saline) group. The PBS group was the control group. After longitudinal tenotomy in both groups of rabbits, in the IRAP group IL-1Ra was applied locally, whereas PBS was applied in the control group. …