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Full-Text Articles in Medicine and Health Sciences
Radiation Effects On Dopamine-Mediated Prepulse Inhibition In The C57bl/6 Mouse, Cara Nicole Zuccarelli Miller
Radiation Effects On Dopamine-Mediated Prepulse Inhibition In The C57bl/6 Mouse, Cara Nicole Zuccarelli Miller
Loma Linda University Electronic Theses, Dissertations & Projects
This study examined the effects of proton and gamma radiation on a dopamine-dependent sensory gating mechanism: prepulse inhibition of the startle reflex. The purpose of this research was to describe potential hazards of proton radiation to the central nervous system in long-term space fight and for proton therapy patients. Results from previous research indicate that startle behavior is modified by proton and iron radiation. Forty-eight 10-½ week old, male C57BL/6 mice were used to characterize the optimal parameters for the model (prepulse duration, probe duration, and stimulus-onset-asynchrony). Three hundred and fifty two mice were used to characterize the time course …
Hybridization Between The Watersnakes Nerodia Sipedon And Nerodia Fasciata, In The Carolinas: A Morphological And Molecular Approach, Konrad Mebert
Hybridization Between The Watersnakes Nerodia Sipedon And Nerodia Fasciata, In The Carolinas: A Morphological And Molecular Approach, Konrad Mebert
Biological Sciences Theses & Dissertations
A few traditionally applied diagnostic characters of color pattern were compared with an additional set of morphological and genetic characters to evaluate differences between Nerodia sipedon and N. fasciata and to study the dynamics across their hybrid zone in the Carolinas. Many of the morphological characters exhibited significant interspecific differences, although only the number of dorsally complete crossbands (CBa) was diagnostic by itself. A discriminant function analysis of morphological characters was successful in separating both taxa. Species-specific nuclear markers, identified by the AFLP (Amplified Fragment Length Polymorphism) technique were nearly fixed and served as diagnostic markers. They revealed extensive introgression …
The Short-Term Effects Of Grade 1 And 2 Joint Mobilizations On Subject Pain Range Of Motion And Muscle Activity In The Pathological Lumbar Spine, Sean Hanrahan
Human Movement Sciences & Special Education Theses & Dissertations
The purpose of this study was to examine the short-term effects of Grades 1 and 2 posteroanterior joint mobilizations (JM) at the pathological lumbar spine on subject pain, range of motion (ROM), and muscle force. All subjects were determined to have sustained mechanical dysfunction of the lumbar spine of less than 48 hours as assessed through a standardized evaluation. Subjects were randomly assigned to a group; the control group received ice and stretching while the experimental group received JM in addition to ice and stretching. The JM's were performed at 3 consecutive lumbar segments surrounding the area of greatest discomfort. …
Detection Of Forces And Body Load In Standing And Walking In The American Cockroach, J. Adam Noah
Detection Of Forces And Body Load In Standing And Walking In The American Cockroach, J. Adam Noah
Theses, Dissertations and Capstones
Sense organs in the legs that detect body weight are an important component in the regulation of posture and locomotion. This thesis seeks to gain an understanding of how body weight is detected by sense organs of the legs, and determine how this information influences muscle activities in standing and walking. The first study tested the ability of tibial campaniform sensilla (receptors that monitor forces in the cockroach leg) to encode variations in body load using magnets attached to the thorax. Recordings of sensory activities in freely standing animals showed that proximal tibial sensilla (oriented perpendicular to the leg long …
Mechanisms Underlying Protection Against Rt-2 Gliomagenesis In Rat Brain Utilizing Primary And Secondary Vaccination, Andrea M. Lister
Mechanisms Underlying Protection Against Rt-2 Gliomagenesis In Rat Brain Utilizing Primary And Secondary Vaccination, Andrea M. Lister
Theses and Dissertations
Primary brain tumor affects some 18,000 adults in the United States each year (Silverberg et al., 1990; Merchant et al., 1997) and over 30% are high-grade anaplastic astrocytoma or glioblastoma multiforme (GBM) (Parney et al., 1997). According to Kruse et al., 1989, the treatment of patients with recurrent or persistent high-grade gliomas represents a major therapeutic challenge. The use of conventional therapy consisting of surgery, followed by radiation therapy and chemotherapy for gliomas, has been relatively ineffective (Jaecle et al., 1994) despite the fact that these therapies are cytoreductive in nature (Black, 1991). Most malignancies will recur locally but may …