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Full-Text Articles in Medicine and Health Sciences

Group-Based Exercise And Cognitive-Physical Training In Older Adults With Self-Reported Cognitive Complaints: The Multiple-Modality, Mind-Motor (M4) Study Protocol, Michael A. Gregory, Dawn P. Gill, Erin M. Shellington, Teresa Liu-Ambrose, Ryosuke Shigematsu, Guangyong Zou, Kevin Shoemaker, Adrian M. Owen, Vladimir Hachinski, Melanie Stuckey, Robert J. Petrella Jan 2016

Group-Based Exercise And Cognitive-Physical Training In Older Adults With Self-Reported Cognitive Complaints: The Multiple-Modality, Mind-Motor (M4) Study Protocol, Michael A. Gregory, Dawn P. Gill, Erin M. Shellington, Teresa Liu-Ambrose, Ryosuke Shigematsu, Guangyong Zou, Kevin Shoemaker, Adrian M. Owen, Vladimir Hachinski, Melanie Stuckey, Robert J. Petrella

Anatomy and Cell Biology Publications

Background: Dementia is associated with cognitive and functional deficits, and poses a significant personal, societal, and economic burden. Directing interventions towards older adults with self-reported cognitive complaints may provide the greatest impact on dementia incidence and prevalence. Risk factors for cognitive and functional deficits are multifactorial in nature; many are cardiovascular disease risk factors and are lifestyle-mediated. Evidence suggests that multiple-modality exercise programs can provide cognitive and functional benefits that extend beyond what can be achieved from cognitive, aerobic, or resistance training alone, and preliminary evidence suggests that novel mind-motor interventions (i.e., Square Stepping Exercise; SSE) can benefit cognition and …


Better Cognitive Control Of Emotional Information Is Associated With Reduced Pro-Inflammatory Cytokine Reactivity To Emotional Stress, Grant S. Shields, Shari Young Kuchenbecker, Sarah D. Pressman, Ken D. Sumida, George M. Slavich Jan 2016

Better Cognitive Control Of Emotional Information Is Associated With Reduced Pro-Inflammatory Cytokine Reactivity To Emotional Stress, Grant S. Shields, Shari Young Kuchenbecker, Sarah D. Pressman, Ken D. Sumida, George M. Slavich

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Stress is strongly associated with several mental and physical health problems that involve inflammation, including asthma, cardiovascular disease, certain types of cancer, and depression. It has been hypothesized that better cognitive control of emotional information may lead to reduced inflammatory reactivity to stress and thus better health, but to date no studies have examined whether differences in cognitive control predict pro-inflammatory cytokine responses to stress. To address this issue, we conducted a laboratory-based experimental study in which we randomly assigned healthy young-adult females to either an acute emotional stress (emotionally evocative video) or no-stress (control video) condition. Salivary levels of …