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Medicine and Health Sciences Commons

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Anatomy

Theses and Dissertations

2011

Spinal Cord Injury

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Assessing The Role Of Polyethylene Glycol (Peg) In Improving Functional Recovery Following Spinal Cord Injury, Dustin Dalton Jul 2011

Assessing The Role Of Polyethylene Glycol (Peg) In Improving Functional Recovery Following Spinal Cord Injury, Dustin Dalton

Theses and Dissertations

Injury to the spinal cord results in the disruption of signal transmission between the brain and distal targets. It often presents with the loss of motor function and sensory perception below the level of injury. There are many obstacles following injury that must be overcome in order to encourage axon regeneration and improve functional recovery. A combinatorial approach is necessary to combat physical and chemical barriers to recovery. The fluid filled cyst that forms in the majority of spinal cord injuries presents a physical barrier that we treat with our electrospun bridges. We implanted our bridges into female Long Evans …