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Full-Text Articles in Medicine and Health Sciences

The Role Of Glutaminase And Extracellular Vesicles In Macrophages And Microglia, Beiqing Wu Aug 2016

The Role Of Glutaminase And Extracellular Vesicles In Macrophages And Microglia, Beiqing Wu

Theses & Dissertations

Glutamate serves as a crucial excitatory neurotransmitter that is essential for the proper functioning of the brain. However, excess levels of glutamate are neurotoxic and contribute to the pathogenesis of various neurodegenerative diseases, inducing HIV-1 associated neurocognitive disorders (HAND). Glutaminase 1 (GLS1) is an important mitochondrial enzyme responsible for producing glutamate from glutamine. GLS1 is upregulated during HAND and released from mitochondria to cytosol and extracellular space. However, why and how GLS1 is released remains unknown. In chapter II, we demonstrated that extracellular vesicles (EVs) carry GLS1 as cargos from cytosol to extracellular space during HIV infection and innate immune …


Gross Anatomy Dissection Videos: Effect On Student Dissection Confidence And Laboratory Examination Scores, Kevin J. Selting May 2016

Gross Anatomy Dissection Videos: Effect On Student Dissection Confidence And Laboratory Examination Scores, Kevin J. Selting

Theses & Dissertations

As medical colleges across the world experience cadaver shortages, faculty shortages, and decreased time allotted to teaching gross anatomy, a need for different teaching modalities has emerged. New ways of teaching are being studied to optimize efficiency and to acquire the same, or better, student outcomes as before the previously mentioned variables became prevalent. This was the stimulus for our research. Dissection videos were made, closely adhering to the dissections performed by Physician Assistant, Physical therapy, and Medical students at the University of Nebraska Medical Center (UNMC). The current Gross Anatomy course at UNMC involves four written examinations covering material …


Utilization Of Dissection Videos In Graduate-Level Gross Anatomy Education: An Analysis Of Student Confidence, Utilization, And Scoring Outcomes, Jessica Gamerl May 2016

Utilization Of Dissection Videos In Graduate-Level Gross Anatomy Education: An Analysis Of Student Confidence, Utilization, And Scoring Outcomes, Jessica Gamerl

Theses & Dissertations

The use of videos in anatomy education has become a potential tool for learning by students. It is currently unclear if using videos that show how to perform a dissection can have an impact on student practical scores. This thesis attempted to address that question as well as address how videos can impact student confidence levels and how students might implement videos into their study strategies. A set of high definition videos was made following the specific steps of a dissector guide and provided to students prior to their third and fourth lab practicals. A series of three surveys was …