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Full-Text Articles in Medicine and Health Sciences
Fibrocystin/Polyductin, Found In The Same Protein Complex With Polycystin-2, Regulates Calcium Responses In Kidney Epithelia, Shizuan Wang, Jingjing Zhang, Surya M. Nauli, Xiaogang Li, Patrick G. Starremans, Ying Luo, Kristina A. Roberts, Jing Zhou
Fibrocystin/Polyductin, Found In The Same Protein Complex With Polycystin-2, Regulates Calcium Responses In Kidney Epithelia, Shizuan Wang, Jingjing Zhang, Surya M. Nauli, Xiaogang Li, Patrick G. Starremans, Ying Luo, Kristina A. Roberts, Jing Zhou
Pharmacy Faculty Articles and Research
Recent evidence suggests that fibrocystin/polyductin (FPC), polycystin-1 (PC1), and polycystin-2 (PC2) are all localized at the plasma membrane and the primary cilium, where PC1 and PC2 contribute to fluid How sensation and may function in the same mechanotransduction pathways. To further define the exact subcellular localization of FPC, the protein product encoded by the PKHD1 gene responsible for autosomal recessive polycystic kidney disease (PKD) in humans, and whether FPC has direct and/or indirect cross talk with PC2, which, in turn, is pivotal for the pathogenesis of autosomal dominant PKD, we performed double immunostaining and coimmunoprecipitation as well as a microfluorimetry …
Making Some Bones About It, Roxanne Greitz Miller, Frank Frisch
Making Some Bones About It, Roxanne Greitz Miller, Frank Frisch
Education Faculty Articles and Research
The article discusses the importance of bone tissue to human beings and the ways to help students to understand its functions. The bone tissue forms the human skeleton to produce varied motions such as walking and talking. In addition, it protects the vital organs of a person and contributes the development of blood. The bone is composed of bone matrix, a dense material occupied by calcium and potassium salts. The matrix comprises several cell types including osteoblasts, osteocytes and osteoclasts. According to the author, a continuous influx of new calcium is necessary because of the constant remodeling of bone tissue. …
Influence Of A Functional Knee Brace And Exercise On Lower Extremity Kinematics During Jogging, Brian M. Campbell, Daniel Cipriani, James A. Yaggie
Influence Of A Functional Knee Brace And Exercise On Lower Extremity Kinematics During Jogging, Brian M. Campbell, Daniel Cipriani, James A. Yaggie
Physical Therapy Faculty Articles and Research
ABSTRACT Context: Functional knee braces (FKB) are used prophylactically and in rehabilitation to aide in the functional stability of the knee joint. Objective: To determine if alterations in sagittal plane lower extremity kinematics remain evident throughout a one hour period in healthy individuals. Design: 2X5 repeated measures design. Setting: Biomechanics Laboratory. Subjects: Twenty subjects (14 male and 6 female, mean age 26.5±7 yrs; height 172.4±13 cm; weight 78.6±9 kg), separated into braced (B) and no brace (NB) groups. Intervention: A one-hour exercise program divided into three 20 minute increments. Main Outcome Measures: Synchronized three-dimensional …