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Life Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Genetics

2015

Physical Sciences and Mathematics

Articles 1 - 3 of 3

Full-Text Articles in Life Sciences

Spectral Gene Set Enrichment (Sgse), H Robert Frost, Zhigang Li, Jason H. Moore Mar 2015

Spectral Gene Set Enrichment (Sgse), H Robert Frost, Zhigang Li, Jason H. Moore

Dartmouth Scholarship

Gene set testing is typically performed in a supervised context to quantify the association between groups of genes and a clinical phenotype. In many cases, however, a gene set-based interpretation of genomic data is desired in the absence of a phenotype variable. Although methods exist for unsupervised gene set testing, they predominantly compute enrichment relative to clusters of the genomic variables with performance strongly dependent on the clustering algorithm and number of clusters. We propose a novel method, spectral gene set enrichment (SGSE), for unsupervised competitive testing of the association between gene sets and empirical data sources. SGSE first computes …


Recent Trends In Breeding Of Tropical Grass And Forage Species, J. S. Sandhu, Dinesh Kumar, Vijay Kumar Yadav, Tejveer Singh, R. P. Sah, Auji Radhakrishna Jan 2015

Recent Trends In Breeding Of Tropical Grass And Forage Species, J. S. Sandhu, Dinesh Kumar, Vijay Kumar Yadav, Tejveer Singh, R. P. Sah, Auji Radhakrishna

IGC Proceedings (1997-2023)

Germplasm enrichment in major tropical grasses and their characterization for emerging environmental challenges have been major focussed area in the recent past. Breeding efforts in tropical grasses are still limited to few selected species viz. Panicum spp, Cenchrus spp, Pennisetum spp and Bracharia spp and all other grasses use of land races for varietal development through selection have been major source of improvement. The pace of breeding efforts in the tropical grasses have been slowed because of many inherent characteristics viz. apomixis, poor seed set, high photo and thermo sensitivity often creating problem in designing and implementing an effective breeding …


Impact Of Market Forces On Product Quality And Grassland Condition, David L. Michalk, Jianping Wu, Warwick B. Badgery, David R. Kemp Jan 2015

Impact Of Market Forces On Product Quality And Grassland Condition, David L. Michalk, Jianping Wu, Warwick B. Badgery, David R. Kemp

IGC Proceedings (1997-2023)

Meeting demands for livestock products which are predicted to more than double during the next 20 years, is central to the challenge of feeding the world sustainably. Smallholders will play a key role in achieving global security in animal protein. However, this requires a shift from subsistence to market-oriented farming where production efficiency not the number of livestock is the key focus with the aim of producing ‘more from less’. For grassland-based ruminant production, reducing stocking rate from current unsustainable levels under subsistence management is an essential first step to producing more production and profit from fewer animals. This is …