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Biology

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Identification Of A Hybrid Lethal Gene On The X Chromosome Of Caenorhabditis Briggsae, John Kelly Dougherty Jan 2019

Identification Of A Hybrid Lethal Gene On The X Chromosome Of Caenorhabditis Briggsae, John Kelly Dougherty

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Two closely related Caenorhabditis species, C. briggsae and C. nigoni are cross fertile and produce viable adult progeny. From C. nigoni mothers, F1 adult females are viable and fertile, F1 males are viable but sterile. In crosses that utilize C. nigoni males and C. briggsae hermaphrodites produce viable adult F1 females but F1 males arrest during embryogenesis. A mutation in the Cbr-him-8 gene is a recessive maternal-effect suppressor of male-specific lethality. Hybrid crosses with cbr-him-8 mutant mothers produce viable adult male progeny. The HIM-8 protein in C. elegans is required for the pairing of X-chromosomes during meiosis. This function is …


Multi-Locus Evidence Of A Late Pleistocene Divergence And Sex-Biased Dispersal In The North American Wood Duck (Aix Sponsa), Christopher T. Bigley Jan 2011

Multi-Locus Evidence Of A Late Pleistocene Divergence And Sex-Biased Dispersal In The North American Wood Duck (Aix Sponsa), Christopher T. Bigley

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The Pleistocene was characterized by fluctuations in climate causing repeated advances and retreats of glacial ice. The advancing ice sheets caused habitat fragmentation which initiated population divergence and speciation events between eastern and western avian populations within northern temperate forests. Based on mitochondrial DNA (mtDNA) control region sequences, North American Wood Duck (Aix sponsa) populations fit this model of divergence. However, mtDNA is maternally inherited, and thus may not reflect the genomic history of this species, because of male biased-dispersal, selection, or stochastic lineage sorting. To test the "Late Pleistocene divergence" hypothesis, I sequenced 11 independent nuclear introns (nuDNA) for …