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Full-Text Articles in Life Sciences
Integration Of Raman Spectroscopy And Python-Based Data Analysis For Advancing Neurobiological Research, Natalie E. Dunn
Integration Of Raman Spectroscopy And Python-Based Data Analysis For Advancing Neurobiological Research, Natalie E. Dunn
Doctoral Dissertations
The field of Raman spectroscopy continues to expand into biological applications due to its usefulness as a non-invasive technique that can be utilized qualitatively and quantitatively. However, the inherent weakness of Raman scattering leads to the need for each collected spectra to undergo a preprocessing step to remove noise, background drift, and cosmic rays. Biological research in particular needs large datasets due to the increased variability in samples. As datasets grow, the need to perform preprocessing on each individual spectra becomes daunting. Often, these steps are done by hand with the help of specialized software programs. Preprocessing can be accelerated …
How Akron Affects The Water Quality Of The Cuyahoga River, Allyson Darst
How Akron Affects The Water Quality Of The Cuyahoga River, Allyson Darst
Williams Honors College, Honors Research Projects
The purpose of this study was to analyze whether the city of Akron had negative effects on the Cuyahoga river, and determine if the Cuyahoga River was naturally able to remediate these effects downstream. The pollutants measured in this study include hardness, bromine, residual chlorine, iron, copper, lead, nitrate, nitrite, ammonium chloride, total chlorine, fluoride, carbonate, pH, total alkalinity and cyanuric acid. This study was done using water testing strips (JNW Direct) to test the water at four different locations along the Cuyahoga River downstream (North) of Akron. This study found that the city of Akron does have a negative …
Ahr Expression On Rorc-Expressing Immune Cells Is Essential For I3c-Mediated Protection Against Colitis, Michal C. Williams
Ahr Expression On Rorc-Expressing Immune Cells Is Essential For I3c-Mediated Protection Against Colitis, Michal C. Williams
Senior Theses
Colitis is an inflammatory bowel disorder (IBD) whose etiology is attributed to modification in the luminal microbiota and dysregulation in the immune response. Indole is a signaling molecule which is naturally produced by gut luminal microbiota. Indole-3- carbinol (I3C) is a compound commonly found in vegetables and a ligand for the aryl hydrocarbon receptor (AhR). Previous studies have detected decreased expression and activation on the AhR receptor in colitis patients, thought to possibly alter gut microbiota metabolism, subsequently promoting colitis. 1 AhR, expressed in a variety of immune and epithelial cells, contributes to gut homeostasis by affecting vital mediators such …
Pectin And Alginate Extraction To Treat Liquid Cafo Manure, Clare Sunderman
Pectin And Alginate Extraction To Treat Liquid Cafo Manure, Clare Sunderman
Honors Projects
For this project, various extraction methods were used to extract pectin from Pastinaca Sativa and alginate from Macrocystis. These extractions were then dried and used in treating 250mL of manure along with a CaCl2 or FeCl3 coagulant. It was found that CaCl2 was not as effective as FeCl3 in coagulating manure. But the results obtained suggest that pectin and alginate obtained with a simpler extraction method is just as effective as the highly purified and refined pectin and alginate produced for the food industry, in the treatment of CAFO manure. The liquid portion of the …
An Evaluation Of Elemental Composition Of Soils Associated With Ground Nesting Ants In The Family Formicidae In Somerset County, Maine, Haley H. Depner
An Evaluation Of Elemental Composition Of Soils Associated With Ground Nesting Ants In The Family Formicidae In Somerset County, Maine, Haley H. Depner
All Student Scholarship
Ants are keystone organisms and engineers in many ecosystems, playing an important role in nutrient cycling and rearrangement of organic and inorganic materials through foraging, waste management and, in subterranean species, nest construction and maintenance. In this study, I conducted elemental analysis of soils for calcium, copper, iron, potassium, manganese and zinc in and around the colonies of subterranean nesting ants. The two-step analysis used in this study utilizes the efficiency of X-Ray Fluorescence (XRF) Spectrometry to look for overall trends in elemental composition followed by Flame Atomic Absorbance (AA) to achieve higher resolution of select elements of interest as …
Biomimetic Macromolecules For Macrophage Targeting And Modulation, Joshua Whited
Biomimetic Macromolecules For Macrophage Targeting And Modulation, Joshua Whited
ETD Archive
Carbohydrate recognition has come to the forefront of biological aiming to uncover the mechanisms of physiological and pathological processes. Cell surface glycans are involved in processes including cellular adhesion, cell signaling, and immune response. A new approach for profiling cell surface glycans has great potential for a wide range of biomedical applications. Lectins have been conventionally used to determine the structure and function of glycoproteins, however, their numbers are still restricted compared to the number of glycan structures. Boronic acid has proven a remarkable small molecule capable of binding diols in aqueous solution. This interaction indicates boronic acid derived molecules …
The Function Of Renalase, Brett Allen Beaupre
The Function Of Renalase, Brett Allen Beaupre
Theses and Dissertations
Renalase was originally reported to be an enzyme secreted into the blood by the kidney to lower blood pressure and slow heart rate. Despite multiple reports claiming to confirm this activity in vivo there has been considerable discord in regards to the reaction catalyzed by renalase. The structural topology of renalase resembles that of known flavoprotein oxidases, monooxygenases and demethylases, but the conserved active site residues are unique to renalase. It has been reported that the catalytic function of renalase is to oxidize circulating catecholamines, however in vitro studies have failed to demonstrate a catalytic activity in the presence of …
The Alcohols, Charles E. Baker
The Alcohols, Charles E. Baker
Manuscript Thesis Collection
A study of Alcohols and the human body's reactions to them.