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Full-Text Articles in Life Sciences

The Role Of Foxd1 In Clear Cell Renal Cell Carcinoma, Kyle H. Bond May 2022

The Role Of Foxd1 In Clear Cell Renal Cell Carcinoma, Kyle H. Bond

Electronic Theses and Dissertations

Renal cell carcinoma (RCC) is the 8th most common cancer in the United States, with the clear cell variant (ccRCC) being the most prevalent. Over 14,000 people die every year to RCC, with rates continuing to increase with an aging general population. Patients suffering from metastatic RCC (mRCC) have extremely poor prognoses, with a 5-year survival of only 11.2%. Current treatment options include resection of primary lesions, tyrosine kinase inhibition (Sunitinib, Pazopanib), mTOR inhibition (Temsirolimus, Everolimus), and immune checkpoint inhibition (Nivolumab, Atezolizumab). Recent attention has been drawn to inhibition of transcription factors like HIF2α (Belzutifan). There is a need …


Thinking Beyond The Fried Egg Model: How Accurately Do Students Perceive Cells In A Living Context?, Milissa Knox Dec 2015

Thinking Beyond The Fried Egg Model: How Accurately Do Students Perceive Cells In A Living Context?, Milissa Knox

Electronic Theses and Dissertations

This exploratory study investigated three aspects of introductory undergraduate biology students’ understanding about cells. The study, which took place at the University of Maine with voluntary students in Basic Biology (“BIO100”) in the summer and fall of 2009, examined (1) students’ pre-course perceptions of cells as they exist in a living context and (2) gains in students’ perception and knowledge about cells after completing the one-semester course (BIO100). Results are based on lecture exam scores, pre-post surveys developed as a part of this thesis, and interviews with two groups of biology students. A total of 498 students participated in the …


Gall Aphids Of The Elm, Edith M. Patch Jun 1910

Gall Aphids Of The Elm, Edith M. Patch

Electronic Theses and Dissertations

A thesis presented to the faculty of the University of Maine by Edith M. Patch for the degree of Master of Science in Biology, Orono, Maine, June, 1910.