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Biology

Biochemistry, Biophysics, and Structural Biology

Theses and Dissertations

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Full-Text Articles in Life Sciences

The Function Of Renalase, Brett Allen Beaupre Aug 2016

The Function Of Renalase, Brett Allen Beaupre

Theses and Dissertations

Renalase was originally reported to be an enzyme secreted into the blood by the kidney to lower blood pressure and slow heart rate. Despite multiple reports claiming to confirm this activity in vivo there has been considerable discord in regards to the reaction catalyzed by renalase. The structural topology of renalase resembles that of known flavoprotein oxidases, monooxygenases and demethylases, but the conserved active site residues are unique to renalase. It has been reported that the catalytic function of renalase is to oxidize circulating catecholamines, however in vitro studies have failed to demonstrate a catalytic activity in the presence of …


Genetic Stock Identification And Migration In Black Sea Bass (Centropristis Striata) Along The Western Atlantic Coast And Gulf Of Mexico, Justin Francis Lewandowski Jan 2014

Genetic Stock Identification And Migration In Black Sea Bass (Centropristis Striata) Along The Western Atlantic Coast And Gulf Of Mexico, Justin Francis Lewandowski

Theses and Dissertations

The black sea bass, Centropristis striata, is a member of the family Serranidae that is commercially important throughout its range, which extends throughout the western Atlantic (from Cape Cod, Massachusetts to Cape Canaveral, Florida) and Gulf of Mexico (from Mobile Bay, Alabama to Tampa Bay, Florida). There are two known subspecies, C. striata striata in the Atlantic and C. striata melana in the Gulf, and through behavioral and morphological evidence two separate stocks are managed in the Atlantic, north and south of Cape Hatteras, NC. Recent genetic studies on mitochondrial DNA (mtDNA) have supported this. To further investigate the relationships …