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Articles 1 - 4 of 4
Full-Text Articles in Life Sciences
Molecular, Somatic, And Performance Characteristics Of Broilers Exhibiting Woody Breast Myopathy, And The Effects Of Dietary And Challenge Intervention Strategies, Linan Jia
Theses and Dissertations
Woody breast (WB) is a meat quality problem that has caused significant economic losses for the poultry industry. Ross × Ross 708 chicks were randomly assigned to a 3 (diet) × 2 (cocci challenge) × 2 (sex) factorial arrangement of treatments. The three diets included the control diet (corn-soybean meal basal diet), antibiotic diet (basal diet + 6.075 mg bacitracin /kg feed), and probiotic diet (basal diet + 2.2 × 108 CFU Bacillus subtilis PB6 /kg feed). Birds in the cocci challenge treatment group received 20 × the live cocci vaccine as an inoculum on d 14. Growth performance and …
Protecting Intestinal Microenvironment Alleviates Acute Graft-Versus-Host Disease, Zhengcan Zhou, Ting Shang, Xiurong Li, Hongyan Zhu, Yu-Bo Qi, Xin Zhao, Xi Chen, Zhe-Xin Shi, Guixiang Pan, Yue-Fei Wang, Guanwei Fan, Xiumei Gao, Yan Zhu, Benjamin Feng
Protecting Intestinal Microenvironment Alleviates Acute Graft-Versus-Host Disease, Zhengcan Zhou, Ting Shang, Xiurong Li, Hongyan Zhu, Yu-Bo Qi, Xin Zhao, Xi Chen, Zhe-Xin Shi, Guixiang Pan, Yue-Fei Wang, Guanwei Fan, Xiumei Gao, Yan Zhu, Benjamin Feng
Peer Reviewed Articles
Acute gut graft-versus-host disease (aGVHD) is a leading threat to the survival of allogeneic hematopoietic stem cell transplantation (allo-HSCT) recipients. Abnormal gut microbiota is correlated with poor prognosis in allo-HSCT recipients. A disrupted intestinal microenvironment exacerbates dysbiosis in GVHD patients. We hypothesized that maintaining the integrity of the intestinal barrier may protect gut microbiota and attenuate aGVHD. This hypothesis was tested in a murine aGVHD model and an in vitro intestinal epithelial culture. Millipore cytokine array was utilized to determine the expression of proinflammatory cytokines in the serum. The 16S rRNA sequencing was used to determine the abundance and diversity …
Effect Of Long-Term Dietary Fat Quality On Metabolic Health With A Special Focus On Dairy Fat, Allison L. Unger
Effect Of Long-Term Dietary Fat Quality On Metabolic Health With A Special Focus On Dairy Fat, Allison L. Unger
Graduate College Dissertations and Theses
Diet, and particularly dietary fat quality (i.e., fatty acid composition), is a significant modifiable risk factor in the development of metabolic diseases. However, whether the manipulation of long-term dietary fat quality may serve as an effective dietary strategy to mitigate metabolic disease risk during aging is not well defined. Accordingly, this work sought to investigate the role of life-long consumption of bioactive fatty acids from various food sources, and particularly dairy fat, on health maintenance and metabolic disease risk later in life. To address this issue, I assessed how long-term supplementation of dairy fat (butter oil), echium oil, or fish …
Circadian Rhythmicity And Melatonin Sensitivity In The Human Gut Commensal Bacterium Klebsiella Aerogenes, Kinga Graniczkowska
Circadian Rhythmicity And Melatonin Sensitivity In The Human Gut Commensal Bacterium Klebsiella Aerogenes, Kinga Graniczkowska
Theses and Dissertations--Biology
While the expression of circadian rhythms is nearly universal among multicellular eukaryotic organisms, demonstration of this phenomenon in prokaryotes has been largely restricted to photosynthetic cyanobacteria until very recently. Further, growing interest in gastrointestinal microbiomes has revealed a complex temporal relationship between the gastrointestinal clock and the bacterial microbiome within. At least one member of the gut microbiome, Klebsiella (née Enterobacter) aerogenes, responds to the indoleamine hormone melatonin, secreted by the gastrointestinal system itself. Further research revealed that K. aerogenes also expresses a circadian rhythm in motility and gene expression that is temperature compensated. Although rhythmicity is unaltered …