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Effect Of Unaccustomed Eccentric Exercise On Motor Unit Firing Characteristics And The Contralateral Repeated Bout Effect: A Pilot Study, Nicholas Coker
Effect Of Unaccustomed Eccentric Exercise On Motor Unit Firing Characteristics And The Contralateral Repeated Bout Effect: A Pilot Study, Nicholas Coker
Electronic Theses and Dissertations, 2020-
Introduction: Eccentric exercise elicits considerable muscle damage. If a bout of unilateral eccentric exercise is repeated on the ipsilateral or contralateral limb, a repeated bout effect (RBE) may be observed where muscle damage is attenuated. Purpose: To examine whether a RBE exists following repeated bouts of damaging eccentric exercise in the ipsilateral and contralateral limbs, and assess changes to motor unit firing characteristics in both limbs following recovery from an initial bout. Methods: Sixteen untrained men were randomized into exercise (EX) or control (CON) groups. EX performed eccentric exercise of the elbow flexors on the dominant (ipsilateral) limb and repeated …
Mechanotransduction Of Leukocyte Transmigration, Cynthia Aguilar
Mechanotransduction Of Leukocyte Transmigration, Cynthia Aguilar
Electronic Theses and Dissertations, 2020-
The endothelium is among the most mechanically enriched environments in the body. It is exposed to a range of hemodynamic-induced and extracellular forces. Of these extracellular forces, the migration of leukocytes through the endothelium will contribute both to classic immune response and development of certain pathologies. While the path of migration across the endothelium will depend on leukocyte and vascular bed type, recent evidence has suggested that the intercellular mechanical microenvironment and forces are also equally as important to this process. Therefore, we present here a model that mimics specific physiological states of a stagnant hemodynamic flow in which we …