Life Sciences Commons^™

Knowledge Of Minor Discomforts During Pregnancy Among Pregnant Women Attending Maternal And Pediatric Hospital In Soran City, Haroon M. Khalil, Kareem J. Hamad

Polytechnic Journal

A lot of pregnant women experience some common discomforts during their pregnancy which may occur due to hormonal, anatomical, and metabolic changes. Although common discomforts may make the pregnant woman feel ill, pregnancy is a normal physiologic process. The common discomforts include backache, leg cramps, constipation, fatigue, nausea and vomiting, sleep disturbance, heartburn, and increased urinary frequency. To assess the pregnant knowledge of minor discomforts happening during pregnancy, it is planned to conduct the present study. A descriptive study design was carried out from December 2017 to June 2018, using non-probability convenience sampling technique for the selection of 150 mothers …

Knowledge Of Minor Discomforts During Pregnancy Among Pregnant Women Attending Maternal And Pediatric Hospital In Soran City, Haroon M. Khalil, Kareem J. Hamad

Polytechnic Journal

A lot of pregnant women experience some common discomforts during their pregnancy which may occur due to hormonal, anatomical, and metabolic changes. Although common discomforts may make the pregnant woman feel ill, pregnancy is a normal physiologic process. The common discomforts include backache, leg cramps, constipation, fatigue, nausea and vomiting, sleep disturbance, heartburn, and increased urinary frequency. To assess the pregnant knowledge of minor discomforts happening during pregnancy, it is planned to conduct the present study. A descriptive study design was carried out from December 2017 to June 2018, using non-probability convenience sampling technique for the selection of 150 mothers …

Knowledge Of Minor Discomforts During Pregnancy Among Pregnant Women Attending Maternal And Pediatric Hospital In Soran City, Haroon M. Khalil, Kareem J. Hamad

Polytechnic Journal

A lot of pregnant women experience some common discomforts during their pregnancy which may occur due to hormonal, anatomical, and metabolic changes. Although common discomforts may make the pregnant woman feel ill, pregnancy is a normal physiologic process. The common discomforts include backache, leg cramps, constipation, fatigue, nausea and vomiting, sleep disturbance, heartburn, and increased urinary frequency. To assess the pregnant knowledge of minor discomforts happening during pregnancy, it is planned to conduct the present study. A descriptive study design was carried out from December 2017 to June 2018, using non-probability convenience sampling technique for the selection of 150 mothers …

Knowledge Of Minor Discomforts During Pregnancy Among Pregnant Women Attending Maternal And Pediatric Hospital In Soran City, Haroon M. Khalil, Kareem J. Hamad

Polytechnic Journal

A lot of pregnant women experience some common discomforts during their pregnancy which may occur due to hormonal, anatomical, and metabolic changes. Although common discomforts may make the pregnant woman feel ill, pregnancy is a normal physiologic process. The common discomforts include backache, leg cramps, constipation, fatigue, nausea and vomiting, sleep disturbance, heartburn, and increased urinary frequency. To assess the pregnant knowledge of minor discomforts happening during pregnancy, it is planned to conduct the present study. A descriptive study design was carried out from December 2017 to June 2018, using non-probability convenience sampling technique for the selection of 150 mothers …

Pm, Amal Rammah, Kristina W Whitworth, Inkyu Han, Wenyaw Chan, Elaine Symanski

Student and Faculty Publications

There is limited evidence on the role of exposure to chemical constituents of fine particulate matter (PM

Nutrition And Exercise Interventions During Pregnancy: How Important Is Adherence?, Taniya S. Nagpal

Electronic Thesis and Dissertation Repository

Lifestyle interventions (nutrition and exercise) offered during pregnancy may prevent excessive gestational weight gain (EGWG) and improve pregnancy outcomes. The efficacy of previous interventions has been inconsistent as some studies ‘successfully’ achieve their health outcome goals while others have had a null effect. A common limitation reported among ‘unsuccessful’ studies is low adherence. The objective of this dissertation was to execute three independent yet interrelated studies to determine if adherence is a key factor in determining the success of a lifestyle intervention during pregnancy. Study 1 compared adherence to ‘successful’ and ‘unsuccessful’ lifestyle interventions during pregnancy using a systematic review. …

Suppressor Of Cytokine Signaling-3 In Pregnant Females With Or Without Hypertension, Huma Shoukat Ali, Mubeen Ali, Sabah Farhat, Syeda Sadia Fatima

Department of Biological & Biomedical Sciences

Suppression of Cytokine Signalling-3 (SOCS-3) modulates the inflammatory pathways responsible for vascular stability. Therefore, we aimed to estimate SOCS-3 levels in 2nd trimester pregnant females and correlate it with blood pressure. A case control study recruiting (n=111) females was conducted at the Aga Khan University. They were classified as pregnancy induced hypertensives ornormotensive as per American College of Obstetricians and Gynecologists Guidelines. Weight, Body mass index, lipid profile and blood glucose were recorded while SOCS-3 was measured by ELISA. Higher SOCS-3 levels were seen in hypertensive group (30 pg/ml) versus normotensive (16 pg/ml). Both Systolic & diastolic blood pressure (r=0.520; …

Nutrient And Food Group Intakes Of Low-Income Pregnant Women By Race/Ethnicity, Alla M. Hill, Danielle L. Nunnery Phd, Rdn, Ldn, Alice Ammerman Drph, Jigna M. Dharod Phd

Journal of Health Disparities Research and Practice

In an exploratory study, a convenience sample of 148 pregnant women was recruited from a WIC clinic in the southeast region of the U.S. to: 1) Examine and compare daily nutrient and food group intakes of WIC pregnant women to national guidelines, and; 2) Determine racial/ethnic differences in nutrient and food group intakes among WIC pregnant women. Women were selected for the study if they were: ≥ 18 y, in 2^nd trimester of pregnancy, and if they spoke English or Spanish as a first language. Upon recruitment, participants were interviewed to collect information on their socio-demographics, including race/ethnicity. Additionally, …

Simple Strategies For A Healthy Pregnancy, Une Applied Nutrition Program

All Student-Created Educational Resources

This handout gives the audience ideas for meeting the nutritional needs of teens for a healthy pregnancy. Tips for incorporating healthy foods and physical activity into a regular routine are included. The importance of nutrition during an adolescent pregnancy is briefly overviewed.

Prevent The Progression Of Gestational Diabetes After Pregnancy, Yasmin Barakat

All Student-Created Educational Resources

This handout informs the audience about ways to reduce the risk of or even prevent the progression of gestational diabetes into needing insulin medication or after pregnancy. This will include tips on healthy defaults for dietary and lifestyle modifications such as making healthy alternatives easy and more attractive, as well as the role of physical activity in diabetes prevention, and maintaining weight. It will also include information on nutrient needs while pregnant.

Evaluation Of Soluble Tnf-Like Weak Inducer Of Apoptosis (Stweak) Levels To Predict Preeclampsia In Early Weeks Of Pregnancy, Sana Shahid, Erum Khalid, Syeda Sadia Fatima, Ghulam Mustafa Khan

Department of Biological & Biomedical Sciences

Introduction: Soluble tumor necrosis factor-like weak inducer of apoptosis (sTWEAK) is linked to endothelial dysfunction; a key factor in pre-eclamptic pathogenesis. This study aimed to compare sTWEAK levels during pregnancy to assess for its prognostic ability.
Materials and Methods: Sixty three high risk pregnant women were followed up from 12 weeks of gestation till term. Serum levels of sTWEAK and platelet derived growth factor (PlGF), blood pressure, serum glucose, uric acid, urea/creatinine and liver function tests were measured. Subjects were stratified according to the ACOG criteria as women who developed PE, or PIH or remained normotensive at term. A negative …

The Type Of Dietary Fat In An Isocaloric Breakfast Meal Does Not Modify Postprandial Metabolism In Overweight/Obese Pregnant Women, Mary Lesser, Kasuen Mauldin, Lisa Sawrey-Kubicek, Virginia Gildengorin, Janet King

Faculty Publications

Almonds provide a satiating, healthy source of fat and fiber. The postprandial metabolic and satiety response to 2 ounces of nuts or dairy was assessed in 18 overweight/obese women during late pregnancy. Serum glucose, triglycerides, insulin, c-peptide, leptin, ghrelin, and lipoprotein particles were measured prior to and during a 5-h postprandial period following the consumption of an isocaloric breakfast meal with equivalent amounts of fat from either nuts or dairy on two separate mornings. Satiety was assessed by visual analogue scale (VAS) questionnaires and ad libitum food intake at the end of the study. At 33 weeks gestation, the women …

Effects Of Prenatal Exercise On Fetal Heart Rate, Umbilical And Uterine Blood Flow: A Systematic Review And Meta-Analysis, Rachel J. Skow, Margie H. Davenport, Michelle Mottola, Gregory A. Davies, Veronica J. Poitras, Casey E. Gray, Alejandra Jaramillo Garcia, Nick Barrowman, Victoria L. Meah, Linda G. Slater, Kristi B. Adamo, Ruben Barakat, Stephanie-May Ruchat

Anatomy and Cell Biology Publications

Objective To perform a systematic review and meta-analysis examining the influence of acute and chronic prenatal exercise on fetal heart rate (FHR) and umbilical and uterine blood flow metrics.

Design Systematic review with random-effects meta-analysis and meta-regression.

Data sources Online databases were searched up to 6 January 2017.

Study eligibility criteria Studies of all designs were included (except case studies) if published in English, Spanish or French, and contained information on the population (pregnant women without contraindication to exercise), intervention (subjective or objective measures of frequency, intensity, duration, volume or type of exercise, alone [“exercise-only”] or in combination with other …

Assessment Of Presumed Sterility Of The Human Placenta And Maternal Bladder, Ali Alhousseini

Wayne State University Dissertations

Introduction

Preterm birth is the number one cause of neonatal morbidity and mortality. A causal link has been established between infection and preterm birth. Urinary tract infection is the number one infection in pregnancy. Evaluating the existence of a placental and maternal bladder microbiome is a major scientific and clinical milestone in perinatal medicine.

Methodology and Results

Chapter 2: This is a prospective case control study. 69 placentas were collected in a sterile fashion from six groups of women without infection: Term cesarean not in labor (n=18), term cesarean in labor (n=9), term vaginal (n=21), preterm cesarean not in labor …

Developmental Expression Of Monocarboxylate Transporter 1 And 4 In Rat Liver, Michael Ng, Justin Louie, Jieyun Cao, Melanie A. Felmlee

School of Pharmacy Faculty Articles

PURPOSE: Monocarboxylate transporters (MCT) are proton-coupled integral membrane proteins that control the influx and efflux of endogenous monocarboxylates such as lactate, acetate and pyruvate. They also transport and mediate the clearance of drugs such as valproate and gamma-hydroxybutyrate. CD147 functions as ancillary protein that chaperones MCT1 and MCT4 to the cell membrane. There is limited data on the maturation of MCT and CD147 expression in tissues related to drug distribution and clearance. The objective of the present study was to quantify hepatic MCT1, MCT4, and CD147 mRNA, whole cell and membrane protein expression from birth to sexual maturity.

METHODS: Liver …

Gentamicin-Modified Nanocarriers For Placental Targeted Drug Delivery To Treat Pregnancy-Related Complications, Ali Alfaifi

Wayne State University Dissertations

Diseases of pregnancy are the leading cause of maternal and neonatal morbidity and mortality affecting more than 20% (26 million) of all pregnancies annually. Those diseases include preeclampsia, preterm labor, intrauterine growth restriction and gestational diabetes, many of which are caused by compromised functions of the placenta. Placenta is a specialized organ that is only present during pregnancy where it creates a maternal-fetal interface that is responsible for many functions that contribute to the development of the fetus. Unfortunately, there is currently no treatment for any of those diseases. Our work focuses on the development of a novel nanoplatform that …

The Influence Of Preovulatory Estradiol On Uterine Transcriptomics And Proteomics Around Maternal Recognition Of Pregnancy In Beef Cattle, Emmalee J. Northrop

Electronic Theses and Dissertations

Preovulatory estradiol has been reported to play a crucial role in pregnancy establishment and maintenance, but the mechanism by which estradiol exerts its effects has not been well characterized. Specifically, the interactions between the maternal uterine environment and the developing conceptus can greatly impact pregnancy success or loss. The objective of this dissertation is to determine the effects of preovulatory estradiol exposure on uterine and trophectoderm transcriptomes, and uterine luminal fluid (ULF) protein composition. Beef cows/heifers were synchronized, artificially inseminated (d 0), and grouped into either high (highE2) or low (lowE2) preovulatory estradiol. Uteri were flushed to collect d16 conceptuses …

Nutritional Condition And Physiological Stress Levels Of Elk In The Black Hills, South Dakota, Chadwick P. Lehman, Christopher T. Rota, Joshua J. Millspaugh

Faculty & Staff Scholarship

Percent of body fat and physiological stress are important correlates to wildlife demographics. We studied winter percent of body fat and physiological stress levels for a declining elk (Cervus canadensis nelsoni) population in South Dakota, 2011–2013. We obtained percent of winter body fat, pregnancy status, lactation status, and physiological stress data from 58 adult females (2+ years old). We compared physiological stress level data from 2011 with data collected from this same herd when elk densities were much higher (1995–1997). Our objectives were to determine percent of body fat during winter, examine if winter body fat was correlated with pregnancy …

Associations Between Maternal Physical Activity In Early And Late Pregnancy And Offspring Birth Size: Remote Federated Individual Level Meta‐Analysis From Eight Cohort Studies, S. Pastorino, T. Bishop, S. Crozier, C. Granstrom, K. Kordas, L. Kupers, E. O'Brien, K. Polanska, K. Sauder, M. Zafarmand, R. Wilson, C. Agyemang, P. Burton, C. Cooper, E. Corpeleijn, D. Dabelea, W. Hanke, H. Inskip, F. Mcauliffe, S. Olsen, T. Vrijkotte, S. Brage, A. Kennedy, D. O'Gorman, P. Scherer, K. Wijndaele, N. Wareham, G. Desoye, K. K. Ong

Articles

Objective

Evidence on the impact of leisure time physical activity (LTPA) in pregnancy on birth size is inconsistent. We aimed to examine the association between LTPA during early and late pregnancy and newborn anthropometric outcomes.

Design

Individual level meta‐analysis, which reduces heterogeneity across studies.

Setting

A consortium of eight population‐based studies (seven European and one US) comprising 72 694 participants.

Methods

Generalised linear models with consistent inclusion of confounders (gestational age, sex, parity, maternal age, education, ethnicity, BMI, smoking, and alcohol intake) were used to test associations between self‐reported LTPA at either early (8–18 weeks gestation) or late pregnancy (30+ …

The Effect Of Maternal Dietary Habits During Pregnancy On Neonate Leptin Methylation Patterns And Gestational Age, Sean Fitzpatrick

Legacy Theses & Dissertations (2009 - 2024)

The health of a newborn baby is inextricably linked to the health status of its mother and in turn the mother’s diet during pregnancy. Leptin (LEP) is an adipokine hormone involved in metabolism regulation and has been linked fetal development through the hypothalamic-pituitary-adrenal axis (HPA). Prior work suggests that gestational epigenetic alterations the LEP gene may be sensitive to adverse exposures during pregnancy, which in turn could explain variation in neonate outcomes. However, no prior work has examined this possibility explicitly. The objective of this study was to investigate the association between dietary patterns of mothers during pregnancy and their …

Latent Growth Model Approach To Characterize Maternal Prenatal Dna Methylation Trajectories, Dana Lapato

Theses and Dissertations

Background. DNA methylation (DNAm) is a removable chemical modification to the DNA sequence intimately associated with genomic stability, cellular identity, and gene expression. DNAm patterning reflects joint contributions from genetic, environmental, and behavioral factors. As such, differences in DNAm patterns may explain interindividual variability in risk liability for complex traits like major depression (MD). Hundreds of significant DNAm loci have been identified using cross-sectional association studies. This dissertation builds on that foundational work to explore novel statistical approaches for longitudinal DNAm analyses. Methods. Repeated measures of genome-wide DNAm and social and environmental determinants of health were collected up to six …

A Randomized Trial Of Prenatal N-3 Fatty Acid Supplementation And Preterm Delivery, Maria Makrides, Karen Best, Lisa Yelland, Andrew Mcphee, Shao Zhou, Julie Quinlivan, Jodie Dodd, Elinor Atkinson, Huda Safa, Jacqueline Van Dam, Gustaaf Dekker, Monika Skubisz, Amanda Anderson, Beth Kean, Anneka Bowman, Carly Mccallum, Kara Cashman, Robert Gibson

Health Sciences Papers and Journal Articles

Background: Previous studies have suggested that maternal supplementation with n−3 long-chain polyunsaturated fatty acids may reduce the incidence of preterm delivery but may also prolong gestation beyond term; however, more data are needed regarding the role of n−3 long-chain polyunsaturated fatty acids in pregnancy.

Methods: We performed a multicenter, double-blind, randomized trial in which women who were pregnant with single or multiple fetuses were assigned to receive either fish-oil capsules that contained 900 mg of n−3 long-chain polyunsaturated fatty acids (n−3 group) or vegetable-oil capsules that contained trace n−3 long-chain polyunsaturated fatty acids (control group) daily, beginning before 20 weeks …