Life Sciences Commons^™

Analysis Of The Temporal Patterning Of Notch Downstream Targets During Drosophila Melanogaster Egg Chamber Development, Molly A. Rowe

Honors College Theses

Living organisms require complex signaling interactions and proper regulation of these interactions to influence biological processes. Of these complex networks, one of the most distinguished is the Notch pathway. Dysregulation of this pathway often results in defects during organismal development and can be a causative mechanism for initiation and progression of cancer. Despite previous research entailing the importance of this signaling pathway and the organismal processes that it is involved in, less is known concerning the major Notch downstream targets, especially the onset and sequence in which they are modulated during normal development. As timing of regulation may be linked …