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2019

Theses/Dissertations

Biology

Wright State University

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Full-Text Articles in Life Sciences

Identification Of A Hybrid Lethal Gene On The X Chromosome Of Caenorhabditis Briggsae, John Kelly Dougherty Jan 2019

Identification Of A Hybrid Lethal Gene On The X Chromosome Of Caenorhabditis Briggsae, John Kelly Dougherty

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Two closely related Caenorhabditis species, C. briggsae and C. nigoni are cross fertile and produce viable adult progeny. From C. nigoni mothers, F1 adult females are viable and fertile, F1 males are viable but sterile. In crosses that utilize C. nigoni males and C. briggsae hermaphrodites produce viable adult F1 females but F1 males arrest during embryogenesis. A mutation in the Cbr-him-8 gene is a recessive maternal-effect suppressor of male-specific lethality. Hybrid crosses with cbr-him-8 mutant mothers produce viable adult male progeny. The HIM-8 protein in C. elegans is required for the pairing of X-chromosomes during meiosis. This function is …


Erk3 Negatively Regulates The Il-6/Stat3 Signaling Via Socs3, Astha Shakya Jan 2019

Erk3 Negatively Regulates The Il-6/Stat3 Signaling Via Socs3, Astha Shakya

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Mitogen activated protein kinases (MAPKs) are Ser/Thr kinases that relay the extracellular signal into intracellular responses and regulate several biological responses. They are classified into conventional MAPKs and atypical MAPKs. Extracellular signal regulated kinase 3 (ERK3) is an atypical MAPK that has a single phospho-acceptor site (Ser 189) in its activation motif instead of the canonical Thr-Xaa-Tyr (TXY) motif of conventional MAPK like ERK1/2. ERK3 comprises of a unique C terminal tail and a central C34 domain that further distinguishes it from ERK1/2. Moreover, compared to ERK1/2, much less is known about the upstream activators and the downstream targets of …


Effects Of Coral Reef Habitat Complexity On The Community Composition And Trophic Structure Of Marine Fish Assemblages In Indonesia’S Wakatobi Marine National Park, Kuyer Josiah Fazekas Jr. Jan 2019

Effects Of Coral Reef Habitat Complexity On The Community Composition And Trophic Structure Of Marine Fish Assemblages In Indonesia’S Wakatobi Marine National Park, Kuyer Josiah Fazekas Jr.

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The coral reefs within Indonesia’s Wakatobi Marine National Park support a high diversity of reef-building hard corals and associated marine fish. Climate change threatens to dramatically affect coral reef ecosystems by altering the interactions between reef fish and the specific microhabitats they depend on for survival. To examine the spatially varied effects of habitat complexity on the community composition and trophic structure of marine fish assemblages, I analyzed fish community and habitat complexity data across reef zones. Habitat complexity metrics were: structural complexity, the percentage of hard coral (HC) cover, HC genera richness, HC genera diversity (Shannon index), and HC …


Bat Species Diversity And Habitat Use Assessment With Focus On Endangered Indiana Bats In The Wright State University Woods, Megan R. Rude Jan 2019

Bat Species Diversity And Habitat Use Assessment With Focus On Endangered Indiana Bats In The Wright State University Woods, Megan R. Rude

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The goals of my thesis are to: 1) identify species of bats in Wright State University’s (WSU) campus woods via acoustic surveys to compare to detections from previous years (Chapter 1) (2) analyze occupancy and detection probabilities of Indiana bats in different areas throughout the woods (Chapter 1), and 3) create an acoustical approach to analyze habitat use through bat social calls (Chapter 2). In Chapter 1, I conducted stationary acoustic surveys in the Wright State University woods in hydric (riparian), edge, and old growth habitats to record bat vocalizations. The WSU woods have a diverse bat community as ten …