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Full-Text Articles in Life Sciences

Exploring Secondary Structure In Bacteriophage Programmed Frameshift Elements, Samuel Okabayashi, Sean Mcclory Nov 2019

Exploring Secondary Structure In Bacteriophage Programmed Frameshift Elements, Samuel Okabayashi, Sean Mcclory

HON499 projects

Bacteriophages are viruses that infect bacteria and reproduce using host bacterial components. Part of the bacteriophage reproduction is assembly of the tail complex, which requires two assembly chaperone (TAC) proteins. In many phages the TAC’s are produced from a single gene through a non-canonical process called programmed translational frameshifting (PTF). The SEA-PHAGES program has produced hundreds of TAC genes that are accessible through phagesdb, a database of sequenced and annotated phage genomes. The sequences for the TAC gene were gathered from phagesdb and analyzed using ClustalOmega; a multiple sequence alignment (MSA) tool which revealed several positions where total conservation was …


Urban Stream Syndrome And The Presence Of E. Coli In Philadelphia Streams, Eileen Black Nov 2019

Urban Stream Syndrome And The Presence Of E. Coli In Philadelphia Streams, Eileen Black

HON499 projects

In this experiment, water samples were collected from the Pennypack and Wissahickon Creeks as part of an exploratory study on the presence of microbes, particularly Escherichia coli, in urban streams. Contamination by E. coli may indicate that a creek is polluted and suffering from urban stream syndrome. E. coli was found in both creeks, likely due to their locations near a sewage treatment facility and a farm.


Interview Of Alice L. Hoersch, Ph.D., Alice L. Hoersch Ph.D., Selena Bemak Apr 2019

Interview Of Alice L. Hoersch, Ph.D., Alice L. Hoersch Ph.D., Selena Bemak

All Oral Histories

Alice Lynn Hoersch was born in 1950 in Abington, PA to Albert and Alice Hoersch. She moved to Honey Brook, located in Chester County, PA at two-years-old. Hoersch lived in Honey Brook until she finished graduate school in 1977. She attended Honey Brook Elementary School. She graduated as valedictorian from Twin Valley High School in 1968. Hoersch studied geology at Bryn Mawr College, graduating in 1972. She received both her master’s and Ph.D. in metamorphic petrology from Johns Hopkins University in 1974 and 1977, respectively. The same year she obtained her Ph.D., Hoersch began teaching as an assistant professor of …