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Full-Text Articles in Life Sciences

Proposed Research Project Regulation Of Human Intestinal Microbes To Treat And Manage Anxiety, Madison Rea Oct 2019

Proposed Research Project Regulation Of Human Intestinal Microbes To Treat And Manage Anxiety, Madison Rea

Fall Showcase for Research and Creative Inquiry

This is my proposed research project on the regulation of gut microbiota to help treat anxiety disorders. My proposal talks about using prebiotics and probiotics to regulate anxiety disorders as an alternative to medications that cause horrible side effects.


A Comparison Of Cave Microbial Communities To Cave Roosting Bat Microbiota In El Malpais National Monument, Usa, Nicole A. Caimi Aug 2019

A Comparison Of Cave Microbial Communities To Cave Roosting Bat Microbiota In El Malpais National Monument, Usa, Nicole A. Caimi

Biology ETDs

The arrival of white-nose syndrome (WNS), a devastating fungal disease, has highlighted the need to better understand bat microbiota and how bats acquire their microbiota. To address this need, we investigated how bat microbiota compare to microbiota from the cave walls in two El Malpais National Monument caves. The external surfaces of six roosting bats from each cave, representing four different bat species, and their associated microbial mats were sampled. One to three air samples were taken in each cave. Samples were sequenced using Illumina MiSeq sequencing of the 16S rRNA gene for bacterial diversity and the ITS region for …


Staph Bacteria From First Breath The Interweaving Of The Nasal Microbiome With The Intricate And Complex Nose, Alan L. Gillen Jun 2019

Staph Bacteria From First Breath The Interweaving Of The Nasal Microbiome With The Intricate And Complex Nose, Alan L. Gillen

Alan L. Gillen

Many microbes live in a mutualistic relationship with the human body, make up the human microbiome, and play a role in our health by stimulating and modulating the immune system. Man’s body is “covered” both inside and outside with millions of microbes that play a role in maintaining normal bodily functions and sustaining life in our changing world. The inner nose in the human body is colonized by millions of microbes during the first week of life. This internal colonization of the upper respiratory system is termed our nasal microbiome. Though we cannot see it, this microbiome is important for …


The Wonderfully Made Design Of The Skin And Its Microbiome, Alan L. Gillen Jun 2019

The Wonderfully Made Design Of The Skin And Its Microbiome, Alan L. Gillen

Alan L. Gillen

Many microbes live in a mutualistic relationship with the human body, make up the human microbiome, and play a role in our health by modulating the immune system. Man is “covered” inside and outside his body with millions of microbes to maintain normal bodily functions and sustain life in our changing world. The skin is the largest organ in the human body and is colonized by millions of microbes. This external colonization of the integumentary system is termed our skin microbiome. Man cannot see it (except with a microscope), but we need it for normal functioning, certainly in a pathogenic …


Exploring The Effects Of Gut Microbiota With The Association Of Parkinson’S Disease, Kristina Babic May 2019

Exploring The Effects Of Gut Microbiota With The Association Of Parkinson’S Disease, Kristina Babic

BIO 410 Spring 2019 Research Papers

Parkinson’s disease is a common neurodegenerative disorder. It is associated with the central nervous system that affects movement, it often includes tremors, stiffness, and inability to plan and think. Nerve cell damage in the brain causes lower production of dopamine leading to those symptoms. There is no cure for Parkinson’s disease, but there are medications that can help control the symptoms. Researchers are suggesting that dysbiosis in gut microbiota could lead to the development of a protein called alpha synuclein in the intestines, and through intestinal leakage, this protein could possibly spread pathologically to the brain by the central nervous …


Prebiotics, Probiotics, And Bacterial Infections, Christina C. Tam, Kirkwood M. Land, Luisa W. Cheng Jan 2019

Prebiotics, Probiotics, And Bacterial Infections, Christina C. Tam, Kirkwood M. Land, Luisa W. Cheng

College of the Pacific Faculty Books and Book Chapters

Bacterial pathogens have developed exquisite virulence mechanisms to survive in the host cells. These virulence mechanisms help them bind and internalize into host cells, replicate, and evade the host immune response. The mammalian host itself has developed its own repertoire of weapons to prevent this from happening. One important component of host response in preventing infections in the gut lumen is the diverse commensal microbiota present. Dysbiosis of the gut microbiota has been implicated in the development of many gastrointestinal diseases. A potential therapeutic pathway to solve these diseases would be by providing probiotics and/or prebiotics to help stimulate growth …


Novel Approaches To Evaluate And Enhance Neonatal Calf Gastrointestinal Health And Development, Fernanda Trindade Da Rosa Jan 2019

Novel Approaches To Evaluate And Enhance Neonatal Calf Gastrointestinal Health And Development, Fernanda Trindade Da Rosa

Electronic Theses and Dissertations

Physiological adaptations of the gastrointestinal tract (GIT) epithelial cells as well as methods to manipulate early life GIT microbiota colonization during the neonatal stage, is of great importance to the dairy industry. The first objective of this research was to optimize a method based on evaluation of bovine transcripts in fecal RNA via RTqPCR using L-selectin (SELL) as a marker for polymorphonuclear leukocytes (PMNL), keratin 8 (KRT8) and fatty acid binding protein 2 (FABP2) for GIT enterocytes, and tight junctions in fecal RNA and GIT sections in dairy calves. To test the reliability of the fecal RNA method, fecal and …