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Full-Text Articles in Life Sciences
Genetic And Psychological Factors Interact To Predict Physical Impairment Phenotypes Following Exercise-Induced Shoulder Injury, Paul A. Borsa, Jeffrey J. Parr, Margaret R. Wallace, Samuel S. Wu, Yunfeng Dai, Roger B. Fillingim, Steven Z. George
Genetic And Psychological Factors Interact To Predict Physical Impairment Phenotypes Following Exercise-Induced Shoulder Injury, Paul A. Borsa, Jeffrey J. Parr, Margaret R. Wallace, Samuel S. Wu, Yunfeng Dai, Roger B. Fillingim, Steven Z. George
Faculty Publications
Background: We investigated interactions between genetic and psychological factors in predicting shoulder impairment phenotypes. We hypothesized that pro-inflammatory genes would display stronger relationships compared with pain-related genes when combined with psychological factors for predicting phenotypic changes.
Subjects and methods: Altogether, 190 participants completed a 5-day experimental protocol. An experimental shoulder injury model was used to induce physical impairment, and a priori selected genetic (pain-related, pro-inflammatory) and psychological (anxiety, depressive symptoms, pain catastrophizing, fear of pain, kinesiophobia) factors were included as predictors of interest. Impairment phenotypes were injury-induced deficits in range of motion (ROM) and strength. After controlling for age, sex, …
Spatial Dynamics And Mixing Of Bluefin Tuna In The Atlantic Ocean And Mediterranean Sea Revealed Using Next-Generation Sequencing, Gregory N. Puncher, Alessia Cariani, Gregory E. Maes, Jeroen Van Houdt, Koen Herten, Rita Cannas, Naiara Rodriguez-Ezpeleta, Aitor Albania, Andone Estonba, Molly Lutcavage, Alex Hanke, Jay Rooker, James S. Franks, Joseph M. Quattro, Gualtiero Basilone, Igaratza Fraile, Urtzi Laconcha, Nicolas Goñi, Ai Kimoto, David Macías, Francisco Alemany, Simeon Deguara, Salem W. Zgozi, Fulvio Garibaldi, Isik K. Oray, Firdes Saadet Karakulak, Noureddine Abid, Miguel N. Santos, Piero Addis, Haritz Arrizabalaga, Fausto Tinti
Spatial Dynamics And Mixing Of Bluefin Tuna In The Atlantic Ocean And Mediterranean Sea Revealed Using Next-Generation Sequencing, Gregory N. Puncher, Alessia Cariani, Gregory E. Maes, Jeroen Van Houdt, Koen Herten, Rita Cannas, Naiara Rodriguez-Ezpeleta, Aitor Albania, Andone Estonba, Molly Lutcavage, Alex Hanke, Jay Rooker, James S. Franks, Joseph M. Quattro, Gualtiero Basilone, Igaratza Fraile, Urtzi Laconcha, Nicolas Goñi, Ai Kimoto, David Macías, Francisco Alemany, Simeon Deguara, Salem W. Zgozi, Fulvio Garibaldi, Isik K. Oray, Firdes Saadet Karakulak, Noureddine Abid, Miguel N. Santos, Piero Addis, Haritz Arrizabalaga, Fausto Tinti
Faculty Publications
The Atlantic bluefin tuna is a highly migratory species emblematic of the challenges associated with shared fisheries management. In an effort to resolve the species’ stock dynamics, a genomewide search for spatially informative single nucleotide polymorphisms (SNPs) was undertaken, by way of sequencing reduced representation libraries. An allele frequency approach to SNP discovery was used, combining the data of 555 larvae and young‐of‐the‐year (LYOY) into pools representing major geographical areas and mapping against a newly assembled genomic reference. From a set of 184,895 candidate loci, 384 were selected for validation using 167 LYOY. A highly discriminatory genotyping panel of 95 …