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Articles 1 - 8 of 8
Full-Text Articles in Life Sciences
Symptoms, Infectious Pathway, Treatment, And History Of Rabies In The United States, Paul Beckman-Ellenwood
Symptoms, Infectious Pathway, Treatment, And History Of Rabies In The United States, Paul Beckman-Ellenwood
Honors Theses
Rabies is a virus of the Lyssavirus family that is endemic to almost all parts of the world and claims over 55,000 lives every year. The virus is capable of being vectored through any warm-blooded animal and has a variable incubation time in its hosts. Once the disease finishes incubating and symptoms appear in the host, the disease is always fatal to humans. To prevent this there are several treatments available, but they can be expensive or difficult to obtain in parts of the world that have the most problems with rabies. To solve this vaccines have been created to …
The Linkage Between Hpa Axis Dysregulation And Metabolic Syndrome, Brianna Godlewski
The Linkage Between Hpa Axis Dysregulation And Metabolic Syndrome, Brianna Godlewski
Honors Theses
A diagnosis of Metabolic Syndrome (MSX) requires patients to present with three or more of the following symptoms: elevated fasting blood glucose levels, elevated serum triglyceride levels, low serum HDL levels, elevated blood pressure, and truncal obesity. This pathology shares many similarities with Cushing’s Syndrome (CS) but a diagnosis of CS requires hypercortisolemia. This similarity has led our lab and others to hypothesize that MSX may be a Cushingoid-like state caused by hypersensitivity of the glucocorticoid receptor (GR), a nuclear hormone receptor that is activated when cortisol binds, and or hyperactivity of the enzyme 11beta-hydroxysteroid dehydrogenase (11?- HSD) type 1, …
Interactive Physical And Cognitive Exercise System (Ipaces™): The Neuropsychological Effects For Youth On The Autism Spectrum, Michaela Haller
Interactive Physical And Cognitive Exercise System (Ipaces™): The Neuropsychological Effects For Youth On The Autism Spectrum, Michaela Haller
Honors Theses
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder that affects 1 in 68 children in the United States (Center for Disease Control, 2016). The disorder is characterized by deficits in social interaction, verbal communication, restricted interests, and repetitive behaviors (DSM- V, 2013). While the apparent cause of ASD is biological, the diagnosis remains based on social deficits (Hapé & Frith, 1996). Exercise has been found to improve executive function for children with an Autism Spectrum Disorder, but motivation is an issue and exergames hold promise. This pilot study evaluated an interactive Physical and Cognitive Exercise System (iPACES™), wherein children pedal …
Health Benefits Of A Plant-Based Diet, Jenna Jackson
Health Benefits Of A Plant-Based Diet, Jenna Jackson
Honors Theses
While the rise and spread of Western culture has created remarkable advances in science, healthcare, and technology, it has also brought about a variety of chronic diseases that never once existed. Much of these ailments can be attributed to the typical Western diet, which places heavy emphasis on meats, dairy, and refined grains, contrasting the typical Eastern or Oriental diet which primarily focuses on fruits, vegetables, fish, and whole grains. This dietary transition has resulted in increased glycemic load, increased levels of unhealthy fats and cholesterol, decreased micronutrient and fiber levels, and skewed acid-base and sodium-potassium ratios. All of these …
Synthesis Of A-Cyanostilbenes And Testing Of Their Anticancer Properties, Gabrielle Cook
Synthesis Of A-Cyanostilbenes And Testing Of Their Anticancer Properties, Gabrielle Cook
Honors Theses
This research project involves synthesizing cyanostilbenes and testing their anticancer properties in breast cancer cells. Breast cancer is a global issue, one that great improvement has been found in the last few decades, but also one that remains a large killer. The components of the cyanostilbene hybrids have all been shown to have anticancer properties on their own, and we would like to see if we can increase these properties by combining multiple into a single hybrid. Then these cyanostilbene compounds are tested on Her2+ human breast cancer cells. The goals is to assess whether or not the cyanostilbenes have …
Lactose Intolerance: An Overview Of The Facts And Their Implications, Noelle M. Yeo
Lactose Intolerance: An Overview Of The Facts And Their Implications, Noelle M. Yeo
Honors Theses
Lactose intolerance is often blamed for the symptoms such as bloating, diarrhea, gas, abdominal pain, and nausea, that ail many people. Patients often do not seek proper diagnosis from a physician and create their own treatment plans, severely restricting lactose intake, without professional guidance. Even those who do seek the care of a physician find that diagnosis is complicated by less-than ideal testing and confusion due to the symptoms common to many other conditions. The misconceptions and inability to confirm a diagnosis of lactose intolerance can cause nutrient deficiencies in these patients, as well as begin a pattern of unnecessary …
Crabp1 Regulation Of Fas Rna In Mouse Mammary Gland Ascs, Fabiola De Varona Colon
Crabp1 Regulation Of Fas Rna In Mouse Mammary Gland Ascs, Fabiola De Varona Colon
Honors Theses
Introduction: The cellular retinoic acid binding protein 1 (Crabp1) promotes tumor growth and is expressed in adipocyte stromal cells (ASCs-L) present during lactation. One known function of Crabp1 is the binding and retention of retinoic acid (RA) in the cytoplasm. This can prevent RA regulated transcription of other genes. Research has shown that Crabp1 is also responsible for the inability of ASC-Ls to retain lipid. This study hoped to connect these two functions of Crabp1 and hypothesized that Crabp1 limits lipid accumulation through Fatty acid synthase (FAS) transcriptional regulation. FAS is an example of a gene that is regulated by …
Is Stem Cell Transplantation A Practical Treatment For Macular Degeneration?, Zachary Slepchuk
Is Stem Cell Transplantation A Practical Treatment For Macular Degeneration?, Zachary Slepchuk
Honors Theses
No abstract provided.