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Full-Text Articles in Life Sciences
Investigations Into The Non-Mevalonate Isoprenoid Biosynthesis Pathway's First Two Enzymes Utilizing Hybrid Qm/Mm Techniques, Justin K. White
Investigations Into The Non-Mevalonate Isoprenoid Biosynthesis Pathway's First Two Enzymes Utilizing Hybrid Qm/Mm Techniques, Justin K. White
USF Tampa Graduate Theses and Dissertations
Molecular drug design begins with the identication of a problem to solve. This work identies the growing resistance among human pathogens to current treatments. Once the problem is identied and understood, solutions must be proposed. This one is straight forward, we need new antimicrobial drugs. More specically, we need to identify novel targets to inhibit. A large portion of antibiotics focus on disruption of macromolecular production while only a few target metabolic systems. Finally, you need to propose solutions based on the information gathered. In order to avoid existing resistance, it is important to avoid the macromolecular route and focus …
Thermodynamic And Kinetic Aspects Of Hen Egg White Lysozyme Amyloid Assembly, Tatiana Miti
Thermodynamic And Kinetic Aspects Of Hen Egg White Lysozyme Amyloid Assembly, Tatiana Miti
USF Tampa Graduate Theses and Dissertations
Deposition of protein fibers with a characteristic cross-β sheet structure is the molecular marker associated with human disorders ranging from Alzheimer's disease to type II diabetes and spongiform encephalopathy. Given the large number of non-disease related proteins and peptides that have been shown to form amyloid fibrils in vitro, it has been suggested that amyloid fibril formation represents a generic protein phase transition. In the last two decades it has become clear that the same protein/peptide can assemble into distinct morphologically and structurally amyloid aggregates depending on the solution conditions. Moreover, recent studies have shown that the early stage, oligomeric …
A Program Evaluation Of A Worksite Wellness Initiative For Weight Loss, Nicholas Martinez
A Program Evaluation Of A Worksite Wellness Initiative For Weight Loss, Nicholas Martinez
USF Tampa Graduate Theses and Dissertations
The purpose of this study was to conduct a program evaluation of ACME’s worksite weight loss initiative and collect evidence relative to the efficacy of the program. An anonymous online survey was administered to participants of the weight loss initiative. The survey was designed to gather information relative to the research questions, which explored the initiative’s barriers to participation, alignment of initiative with the goals of participants, utilization of initiative resources, overall strengths, weaknesses, and areas of improvement for the weight loss initiative, as well as the respondents’ general profile for the six dimensions of wellness. Reporting of data included …
Taxonomy, Ecology, And Behavior Of The Kleptoplastic Sea Slug Elysia Papillosa, William Alan Gowacki
Taxonomy, Ecology, And Behavior Of The Kleptoplastic Sea Slug Elysia Papillosa, William Alan Gowacki
USF Tampa Graduate Theses and Dissertations
Sacoglossan sea slugs are one of the best known examples of specialist herbivores in the marine environment and can be found strongly associated with their algal hosts and food sources. Perhaps the most intriguing characteristic of many sacoglossans is their ability to sequester functional chloroplasts from their algal food sources in a process called kleptoplasty. Despite this, there continues to be issues regarding taxonomic identification of species. In turn, the ecological characteristics of many of these slugs, such as algal host and food source preference, as well as their behavioral aspects, have received little attention. A prime example of these …