Life Sciences Commons^™

Multi-Generational Effect Of Western Diet On Colorectal Cancer And Impact Of Green Tea On Cancer Prevention, Sumira Phatak, Canyon Neal, Kevin Contreras, Tess Armbrust, Daphne Rodriguez, Braden Abercrombie, Katie Pontsler, Deanna Larson, Ashli Hunter, Hector Esquer, Jocelyn Cuthbert, Michael Lefevre, Korry Hintze, Robert Ward, Abby Benninghoff

Student Research Symposium

Diet is widely recognized as an important factor in lifetime cancer risk, yet Americans routinely consume foods that are energy-dense and nutrient-poor. Animal model studies to identify functional foods for cancer prevention generally do not account for typical Western dietary patterns with respect to macro- and micronutrient content. The primary objectives of this study were to determine the impact of ancestral and multi-generational consumption of a Western-style diet in a murine model of inflammation-associated colorectal carcinogenesis. Additionally, we sought to determine the efficacy of green tea for prevention of Western diet-enhanced colon tumorigenesis. Previously, our group developed the Total Western …