Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Life Sciences
Virus-Host Co-Evolution: Determining The Origin Of Human Cytomegalovirus Us27 And Us28, Jessica A. Scarborough, Juliet Spencer, John Paul
Virus-Host Co-Evolution: Determining The Origin Of Human Cytomegalovirus Us27 And Us28, Jessica A. Scarborough, Juliet Spencer, John Paul
Creative Activity and Research Day - CARD
G protein-coupled receptors (GPCR) are the largest family of cell surface proteins, found in organisms from yeast to humans. Human cytomegalovirus (HCMV) is a widespread pathogen that is particularly skilled at evading immune detection and defense mechanisms, largely due to extensive co-evolution with its host’s immune system. One aspect of this co-evolution involves the acquisition of four virally encoded GPCR homologs: US27, US28, UL33 and UL78. In this research, phylogenetic analysis was used to investigate the origins of the US27 and US28 genes, which are adjacent in the viral genome. The results indicate that both US27 and US28 share the …
Mass Extinctions Increase Evenness Of Genus Diversity Across Ecological Modes, Catherine Lau
Mass Extinctions Increase Evenness Of Genus Diversity Across Ecological Modes, Catherine Lau
Creative Activity and Research Day - CARD
In the Big Five mass extinctions, species were eliminated from ecological modes (groups of species in the same habitat with the same motility method and feeding strategy) with greater species diversity preceding these events. Using Knope et al.'s (2015) data set of 18,621 marine animal genera, I asked: When diversity rebounds, does it recover to a similar distribution of genus diversity across modes or to a more even distribution spanning different modes? With each event, the difference in diversity among modes decreases, so evenness increases over time. Mass extinctions contribute to the broad range of diversity we see today.