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Full-Text Articles in Life Sciences
Reef Fish Assemblage Structure Variability Off Southeast Florida: Ongoing Research, R. Navarra, Aarti Raja
Reef Fish Assemblage Structure Variability Off Southeast Florida: Ongoing Research, R. Navarra, Aarti Raja
Aarti Raja
No abstract provided.
Integration Of Scientific Concepts Through A Hands-On Learning Program: Science Alive!, T. Gali, Aarti Raja
Integration Of Scientific Concepts Through A Hands-On Learning Program: Science Alive!, T. Gali, Aarti Raja
Aarti Raja
No abstract provided.
Telithromycin. Fresh From The Pipeline, Aarti Raja, J. Lebbos, P. Kirtpatrick
Telithromycin. Fresh From The Pipeline, Aarti Raja, J. Lebbos, P. Kirtpatrick
Aarti Raja
In April 2004, telithromycin (Ketek; Aventis), the first of a new class of antibacterial drugs derived from macrolides, was approved by the US FDA for the treatment of several respiratory-tract infections. After a delay in its approval owing to a need to address potential safety issues, is it likely to now attain the blockbuster status that had originally been widely predicted?
Fcas Service Learning Projects Winter Semester 2013, Aarti Raja, Robert P. Smith, L. Vigesaa
Fcas Service Learning Projects Winter Semester 2013, Aarti Raja, Robert P. Smith, L. Vigesaa
Aarti Raja
No abstract provided.
Interaction Of Hiv Reverse Transcriptase With Structures Mimicking Recombination Intermediates, Aarti Raja, J. Jeffrey, J. J. Destefano
Interaction Of Hiv Reverse Transcriptase With Structures Mimicking Recombination Intermediates, Aarti Raja, J. Jeffrey, J. J. Destefano
Aarti Raja
Interactions between human immunodeficiency virus (HIV) reverse transcriptase (RT) and structures mimicking intermediates proposed to occur during recombination (strand transfer) were investigated. One mechanism proposed for strand transfer is strand exchange in which a homologous RNA (acceptor) "invades" a donor RNA.DNA duplex (replication intermediate) on which DNA synthesis is occurring. The acceptor displaces the donor of the duplex and binds to the DNA. During exchange a transient trimeric structure forms. A model structure was designed with a replication intermediate to which an acceptor RNA was bound. The acceptor was bound to the 5'-end of the DNA over a 54-base region, …
In Vitro Strand Transfer From Broken Rnas Results In Mismatch But Not Frameshift Mutations, Jeffrey J. Destefano, Aarti Raja, Jason V. Christofaro
In Vitro Strand Transfer From Broken Rnas Results In Mismatch But Not Frameshift Mutations, Jeffrey J. Destefano, Aarti Raja, Jason V. Christofaro
Aarti Raja
An in vitro system to compare the fidelity of strand transfers from truncated vs full-length RNAs was constructed. A donor RNA, on which reverse transcriptase (RT)-directed DNA synthesis was initiated, shared homology with an acceptor RNA, to which DNAs initiated on the donor could transfer. All RNAs were derived from the N-terminal portion of the alpha-lac gene. On full-length donors, transfers occurred when DNAs migrated to the acceptor prior to being completed on the donor. On donors that were truncated, most transfers occurred after DNAs reached the end of the donor. Transfer products were amplified by PCR and used to …
Biology On The Go – Science Outreach For K To 12 And Beyond!, A. William, Aarti Raja
Biology On The Go – Science Outreach For K To 12 And Beyond!, A. William, Aarti Raja
Aarti Raja
No abstract provided.