Life Sciences Commons^™

Vitamin D Status And Bone Mineral Density In Female Collegiate Dancers And Cheerleaders, Tara Sue Kenny

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction: An athlete’s bone mineral density reflects their cumulative history of energy availability, physical activity, genetic predisposition for bone health, and menstrual status, as well as nutritional, behavioral, and environmental factors.

Purpose: To determine if bone mineral density (BMD) and nutritional factors in bone health are different in two groups of female athletes who have comparable body size/weight requirements, but who engage in qualitatively different training regimens.

Methods: Participants were female collegiate athletes who were members of the UNLV Dance team (n=10) or Cheer team (n=9), ages 18-22. Participants vitamin D status was assessed by obtaining a finger prick sample …

Scardovia Wiggsiae Prevalence In Orthodontic Patients, Brandon Joseph Streiff

UNLV Theses, Dissertations, Professional Papers, and Capstones

Dental caries has mainly been associated with Streptococcus, Lactobacillus, Actinomyces and Veillonella species. But in recent salivary studies a new cariogenic pathogen, has been identified. This new bacteria, Scardovia wiggsiae (SW), is currently being tested within the UNLV School of Dental Medicine patient population. Although these current studies are being conducted to study its prevalence in both pediatric and adult populations, it has not been evaluated among patients with an altered oral environment as seen in patients with orthodontic appliances. Fixed orthodontic appliances increase the difficulty of removing daily plaque on and in between the teeth with standard oral hygiene …

Television Consumption And Child Obesity: Linking Children's Contemporary Television Use, Physical Activity, And Advertising To Putnam's Displacement Hypothesis, Brittany L. Altamirano

UNLV Theses, Dissertations, Professional Papers, and Capstones

This study observed the relationship between television consumption and child obesity through the theoretical construct of Putnam’s displacement hypothesis. It did so by updating the previous research through the investigation of the displacement of both physical activity and advertisements on contemporary television platforms. The inclusion of Putnam’s displacement hypothesis was to provide a foundational framework, not found in previous literature, to study two important paradigms that were represented in previous research: 1) the displacement of physical activity; and 2) the displacement of traditional advertisement exposure.

Several trends became apparent within previous literature. Previous literature did not include an explicitly stated …

Assessing The Importance Of Nurse Plant Associations To The Growth Of Pre-~Reproductive Yucca Brevifolia, Eric James Chameroy

UNLV Theses, Dissertations, Professional Papers, and Capstones

Facilitation and competition among plant species, in addition to abiotic factors, play an important role in determining plant community structure in arid and semi-arid environments. I conducted a study in Dry Lake Valley, Lincoln County, Nevada, USA to investigate the importance of nurse plant associations to pre-reproductive Yucca brevifolia (Joshua tree). Dry Lake Valley lies within a transition desert between the Mojave and Great Basin Deserts with ecotonal plant communities consisting of species representative of both deserts. A vegetation survey described the communities in which this study was conducted as a Y. brevifolia woodland dominated by an understory of Ephedra …

The Influence Of Transcranial Random Noise Stimulation On Motor Skill Acquisition And Learning In A Modified Golf Putting Task, Lidio Lima De Albuquerque

UNLV Theses, Dissertations, Professional Papers, and Capstones

Transcranial random noise stimulation (tRNS) is a form of non-invasive brain stimulation (NIBS) that has been shown to increase motor performance in simple motor tasks. The purpose of the present study was to determine the influence of tRNS on motor skill acquisition and learning in a complex, modified golf putting task in young adults. Twenty-four (n = 12 per group) healthy young adult males were allocated to either a tRNS group or a SHAM stimulation group. Both groups performed 6 trials of the golf putting task in a baseline testing block, followed by 4 practice blocks of 15 trials. The …

Stable Isotope Analysis Of Bison Latifrons And Paleoecological Inferences, Fabian Ceron Hardy

UNLV Theses, Dissertations, Professional Papers, and Capstones

Bison latifrons was a large Pleistocene herbivore that is traditionally hypothesized to have been adapted to living in forest openings and woodlands. According to this view, the species was primarily a browser of high-growing, woody plants. Very little isotopic work has been conducted on this species, and there have been no prior studies of high altitude localities containing this species. This study aims to address both of these issues.

B. latifrons is known from sites in several states, including California, Idaho, Colorado, Nevada, and Florida, among others. These sites provide diverse examples of this species’ habitat and the opportunity to …

The Effects Of Honeybee (Apis Mellifera) Antimicrobial Peptides On Paenibacillus Larvae, Jasmin Camille Khilnani

UNLV Theses, Dissertations, Professional Papers, and Capstones

American Foulbrood Disease (AFB) is the most detrimental bacterial disease that affects honeybee larvae (Apis mellifera) worldwide. The etiological agent of AFB is the Gram-positive, spore-forming bacterial pathogen, Paenibacillus larvae. Treatment with antibiotics, specifically oxytetracycline, has led to the development of antibiotic resistance in P. larvae. Therefore, there is a pressing need for an alternative treatment method. The overall goal of this project was to test naturally occurring, active antimicrobial peptides (AMPs), which are produced in the adult honeybee, against vegetative P. larvae. These active AMPs could potentially be used as a prophylactic treatment to prevent P. larvae infection of …

The Presence Of Clostridium Difficile On Environmental Surfaces In Healthcare Facilities Pre- And Post-Decontamination Of Patient Rooms, Theresa Trice

UNLV Theses, Dissertations, Professional Papers, and Capstones

Healthcare-associated infections (HAIs) are infections related to receiving medical care. HAIs are responsible for an excess of morbidity and mortality among hospitalized patients. Though most HAIs rates are on the decline, Clostridium difficile infection rates are at an all-time high, primarily due to the persistence of C. difficile spores in the environment. In the United States, Clostridium difficile-related mortality rates per million have increased from 5.7 in 1999 to 23.7 in 2004, with an estimated 26,642 deaths due to Clostridium difficile infections (CDIs). Clostridium difficile is transmitted via the fecal-oral route or aerosolized endospores, but it can also be transmitted …

Paenibacillus Larvae Spore Germination And American Foulbrood Disease Development In Honey Bee Larvae, Israel Alvarado

UNLV Theses, Dissertations, Professional Papers, and Capstones

Honey bee (Apis mellifera) pollination plays an important role in meeting our agricultural needs, yet we are incapable of completely preventing a decline in bee health, partially due to bacterial diseases. American Foulbrood (AFB), a bacterial disease of honey bee larvae, is particularly troublesome because the infectious agent is the bacterial spore of Paenibacillus larvae. Bacterial spores are resistant to extreme temperatures, unaffected by antibiotics, withstand exposure to disinfectants, and can remain dormant for years until they can revert back to vegetative cells.

Our research investigated P. larvae spore germination at the functional and pathogen-host level. We have found that …

Cultivation-Dependent Analysis Of Microorganisms Associated With Various Hydraulic Fracturing Fluids, Anthony Harrington

UNLV Theses, Dissertations, Professional Papers, and Capstones

The overarching goal of this study is to gain more insight to the microbial interactions associated with hydraulic fracturing by studying the culturable microorganisms present in various types of hydraulic fracturing fluids. Extraction of natural gas and other unconventional resources using hydraulic fracturing has increased in the last decade and very few studies have been conducted on the microorganisms associated with the various water types used in the process. From the very few published studies, the only cultivation-dependent method used involved determining the most probable number (MPN) of various metabolic groups, however the researchers failed to ask more in-depth questions …

The Effect Of Sleep On Perceptual Learning And Memory Consolidation, Vanessa Claire Irsik

UNLV Theses, Dissertations, Professional Papers, and Capstones

An ability to segregate speech accurately is essential given that most auditory environments contain other overlapping conversations or environmental noise. While perceiving speech among background noise can be difficult in and of itself, those with hearing impairments can experience considerable difficulty. While training has been shown to benefit perceptual segregation of trained sounds, it is unclear how such training transfers to sounds not included in a training regimen. The current study aimed to address this question by training listeners on a portion of sounds during a vowel segregation task, and subsequently testing on both the trained sounds and untrained sounds. …

Comparing Functional Motor Control And Gait Parameters In Children With Autism To Those Of Age-Matched Peers Who Are Typically Developing, Patricia Stevenson, Samantha Novotny, Jillian May, Christopher Ancell

UNLV Theses, Dissertations, Professional Papers, and Capstones

The purpose of this study was to compare motor performance of children with Autism Spectrum Disorder (ASD) to that of age-matched peers who are typically developing (TD) on motor control tasks plus symmetry and variability of gait parameters across four walking conditions. A sample of convenience of children with ASD (n=6) and peers who are TD (n=6) were recruited. Motor control was assessed using initiation and completion times on the Timed Up and Go (TUG) test. Gait parameters were collected using a computerized walkway under four trial conditions: 1) walking at self-selected velocity (SSV); 2) walking during a tray-carrying task …

Athletes’ Perceptions Of Athletic Trainers Quality Of Care, Chadley Foster

UNLV Theses, Dissertations, Professional Papers, and Capstones

The purpose of this study was to explore student athletes’ perceived satisfaction of care from certified and licensed athletic trainers (ATC) and satisfaction of care between full time and graduate student ATCs at University of Nevada, Las Vegas (n=61). Studies identify satisfaction as a method to measure quality of care and its influence on many aspects of athletes’ success including health outcomes. This is the first study that evaluated multiple aspects of care including type and length of sport participation, academic class status, number of ATCs seen, primary ATC (graduate or full time), number of interactions with primary ATC, injury, …

Oral Vs. Nasal Breathing During Submaximal Aerobic Exercise, Chase Ovila Platt Lacomb

UNLV Theses, Dissertations, Professional Papers, and Capstones

When comparing oral breathing versus nasal breathing more volume of air can be transported through the oral passageway, but nasal breathing can lead to slower respiration rates and cleaner inspired air. The purpose of this study is to find the most efficient mode of breathing during different intensities of submaximal aerobic exercise. There were 9 males and 10 females that completed this study. First test was a VO₂ Max test, 3.0 mph for 3 minutes, with increases in 1.0 mph every minute after that. Using a regression equation running speeds were determined for each individual’s submaximal intensities. The desire …

An Evaluation Of Select Physical Activity Exercise Classes (Pex) On Bone Mineral Density, Tori Michelle Stone

UNLV Theses, Dissertations, Professional Papers, and Capstones

INTRODUCTION: According to the National Institute of Health consensus, Osteoporosis causes premature disability in approximately 44 million people (National Institute of Health [NIH], 2001), 80% of this population being women (Ulrich, Georgiou, Gillis, & Snow, 1999). This chronic disease causes 1.5 million fractures annually, 700,000 occurring at the spine (NIH, 2001). One prevention technique developed in recent years is to build a high peak bone mass during growth and in young adult life (Almstedt, Canepa, Ramirez, & Shoepe, 2011). Several publications positively correlate an increase in BMD with increased amounts of exercise. Bone mineral density can be observed through DEXA …

Leukocyte Responsiveness To Exercise In Hcmv+ Individuals, Jared Nicholas Wilson

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction: Emerging research suggests that the lymphocyte immune response during exercise is amplified in individuals who are positive for human cytomegalovirus (HCMV+). However, the responses of monocytes and neutrophils in HCMV+ individuals are unknown. HCMV, a type of herpes virus, infects 50% or more of the adult population in the United States. This virus can become a cause for concern in individuals who have a compromised immune system, which has been shown to occur after high-intensity exercise.

Purpose: The purpose of this study was to characterize the lymphocyte, monocyte, and neutrophil responses to exercise in HCMV+ individuals.

Methods: Participants were …

Functional Capacity In Schizophrenia: Relationship Among Effort, Reinforcement Learning And Self-Beliefs, Sally J. Vogel

UNLV Theses, Dissertations, Professional Papers, and Capstones

Individuals with schizophrenia exhibit a wide range of complex neurocognitive, psychiatric and behavioral impairments. Recent research suggests that this complex array of symptoms can be at least partially accounted for by dysfunction in more basic mechanisms, such as the ability to learn from positive and negative reinforcement, or the ability to exert adequate effort when completing simple tasks. Evidence also suggests that deficits in these basic mechanisms may contribute to more complex symptoms, such as functional impairment. Also, the relationship between neurocognitive deficits and functional impairment has been found to be mediated by defeatist performance beliefs. However, studies have not …

Validation And Reliability Of The Hexoskin And Fitbit Flex Wearable Bio Collection Devices, Jeffrey Montes

UNLV Theses, Dissertations, Professional Papers, and Capstones

The purpose of this study was to investigate whether the Hexoskin shirt and the wrist worn Fitbit Flex activity monitor were both valid and reliable for the physiological functions they were designed to monitor. Heart rate (beats·min-1), respiratory rate (breaths·min-1), step count, and energy expenditure results were collected for the Hexoskin. Step count and energy expenditure were collected for the Fitbit Flex. 49 adolescent participants performed a walking treadmill protocol at 1.5 mph, 2.5 mph, and 3.5 mph for 3 minutes at each speed. 46 subjects returned to perform the same protocol a second time. 31 of the participants were …

Lead Hazard Control In Henderson, Nevada: Identifying Critical Areas And The Associated Costs, Khaye Gerazel Arcilla Rufin

UNLV Theses, Dissertations, Professional Papers, and Capstones

Lead poisoning is a common, yet preventable childhood health problem in the United States today. Studies show statistically significant (p < .05) associations between higher childhood lead exposure and subsequent negative developmental outcomes. Since 1993, the U.S. Department of Housing and Urban Development (HUD) Lead Hazard Control (LHC) Grant Program has devoted more than $1 billion in funding to several cities.

This study investigated a total of n=75 homes enrolled into the Henderson Lead Hazard Control and Healthy Homes Program (HLHCHHP) from December 2013 – February 2015. A logistic regression was performed to ascertain the frequency of lead-based paint (LBP) found in homes based on the year it was constructed. Of the 75 enrolled and tested for LBP, 58 homes (77.3%) were found to contain LBP and 17 homes (22.7%) did not contain LBP. The significance value of p=0.013 shows that …

In Vitro Studies Of Gold And Gold Silica Nanoparticle Radiosensitization With Kilovoltage X-Rays, Gregory Colarch

UNLV Theses, Dissertations, Professional Papers, and Capstones

Technological advances in the ability to construct and manipulate nanoscale particles have opened up the possibility of using solid metallic nanoparticles and mixed metal nanoshells as a means to increase dose enhancement and treatment efficacy to tumors. In order for nanoparticles to be an effective form of treatment, they must be delivered to tumors in sufficient concentrations so that there is a dose enhancement factor due to ionizing radiation, as well as being essentially non-toxic to healthy cells. Gold nanoparticles and silica-gold nanoshells fit these requirements. Gold has a high atomic number (Z=79), which gives a larger cross section for …

Changes In Sprint Kinetics Or Kinematics Following Static Or Dynamic Stretching, Kristyne Bartel

UNLV Theses, Dissertations, Professional Papers, and Capstones

The purpose of this study was to determine the effects of static or dynamic stretching on hip kinematics and kinetics during intermittent sprinting. To achieve this aim, intermittent sprint athletes were asked to complete either a static or dynamic stretch, followed by a repeated-sprint protocol. Hip joint kinematics and performance measures were evaluated during the sprint, including changes that occurred in these variables over the course of the sprint protocol. In addition, hip flexion torque was measured with an isokinetic dynamometer. Ten male (age = 25±2.3 years, 175±3.2 cm, 76.2±2.7 kg) and female (age = 20±1 years, 166±1.3 cm, 60±1.1 …

A Comparison Of The Effects Of Different Doses Of Gabab Receptor Ligands On Spatial Learning And Memory And Memory Flexibility, Chelcie Heaney

UNLV Theses, Dissertations, Professional Papers, and Capstones

The principal inhibitory neurotransmitter in the brain, gamma amino-butyric acid (GABA), mediates several types of learning and memory. Of the two main receptor subtypes for GABA, the in vivo role of GABAB receptor in learning and memory is less well characterized and the current data often conflict. Based on the current literature, it is unclear, for instance, whether enhancing GABAergic activity via the GABAB receptor could be beneficial for or detrimental to learning and memory. Hippocampally-dependent learning and memory tasks are of particular interest due to their clinical relevance to patients with schizophrenia or Alzheimer’s disease, who exhibit impaired performance …

Comparison Of Muscle Latencies For Diabetic Neuropathy Patients Versus Healthy Controls During A Perturbed Balance Task, Kyle Mefferd

UNLV Theses, Dissertations, Professional Papers, and Capstones

The purpose of this study was to compare muscle latencies for patients diagnosed with diabetic neuropathy versus healthy controls during a perturbed balance task, with a secondary purpose to distinguish postural control strategies the groups used based on the muscle latencies. Five participants diagnosed with diabetic neuropathy (DN; 4 male, 99.7 ± 7.95 kg, 176 ± 9.58 cm, 46.6 ± 16.55 years) and 5 healthy control (HC; 4 male, 100.36 ± 12.61 kg, 173.76 ± 9.66 cm, 47 ± 13.42 years) participants were recruited. Participants granted institutionally approved written consent before participating. Delsys Trigino Wireless EMG sensors were placed on …

Beryllium Is A Potent And Unique Gsk-3Β Inhibitor With Potential To Differentially Regulate Glycogen Synthase And Β-Catenin, Ata Ur Rahman Mohammed Abdul

UNLV Theses, Dissertations, Professional Papers, and Capstones

Glycogen Synthase Kinase-3β (GSK-3β) is an important serine/threonine kinase that phosphorylates/regulates diverse and metabolically important proteins. Some of the important substrates of GSK-3β are glycogen synthase, tau, β-catenin, cyclin D1, axin, c-jun, c-myc, Heat Shock Factor–1, BCL-3, CREB, Histone H1.5, mdm2, p21 (CIP1), pyruvate dehydrogenase and many more. De-regulation of GSK-3β has been implicated in diseases like cancer, Alzheimer’s disease, bipolar disorder and type 2 diabetes mellitus. Currently, GSK-3β is one of the most widely studied proteins and there is a great interest in developing potent and efficient GSK-3β-inhibitors for research as well as therapeutic purposes. We demonstrate that beryllium …

Understanding Perceptions Of Genetically Modified Food Among Natural Food Shoppers In Southern Nevada, Christian Murua-Aceves

UNLV Theses, Dissertations, Professional Papers, and Capstones

Today, 85% of corn, 93% of soybeans, and 88% of cotton in the U.S. are genetically modified (GM). Using laboratory methods, genes from one species, such as a plant, can be transferred to an unrelated species, such as an animal. Genetically modified crops may lead to higher yields, have improved food quality, texture, and nutritional value, and have an increased shelf life.

Despite these promising benefits, the potential health risks relating to the consumption of GM food remain inadequately assessed. Genetically modified food is not subjected to rigorous safety testing, such as epidemiologic studies, to identify potential health risks. Two …

Impact Of Menu Designs And Personal Dietary Behaviors On Young Millennials' Restaurant Menu Choices, Yuan Tian

UNLV Theses, Dissertations, Professional Papers, and Capstones

The global prevalence of obesity has more than doubled since 1980. In response to this health crisis, the U.S. Food and Drug Administration finalized the Menu Calorie Labeling Rule in 2014. It requires that food service chains post Calorie information next to all food items on menus. Young Millennials aged 18-24 reportedly have poor dietary habits, which contributes to obesity rates. This on-line study surveyed 505 young Millennials to evaluate the relationship between young Millennials’ Calorie choices on restaurant menus and various factors, including menu design, personal dietary behaviors, and demographic characteristics. The survey data was analyzed using logistic regression. …

Investigating Single-Leg Landing Strategies And Movement Control Across Changes In Task Demands, Andrew D. Nordin

UNLV Theses, Dissertations, Professional Papers, and Capstones

Variability is an intrinsic characteristic of human movement, with hypothesized connections to neuromotor functioning and mechanisms of injury. The purpose of this study was to evaluate changes in movement variability among kinematic, kinetic, and electromyographic (EMG) variables following mechanical task demand manipulations during single-leg drop landings. Biomechanical outcome variables included 3 kinematic (sagittal, hip, knee, and ankle angles), 4 kinetic (sagittal hip, knee, ankle moments and vertical ground reaction force; GRFz), and 5 EMG variables (gluteus maximus, vastus medialis, biceps femoris, medial gastrocnemius, and tibialis anterior muscles). Mechanical task demands were altered using load and landing height manipulations, computed as …

Reliability Of A Multisegment Foot Model In Shod Running, Austin Coupe

UNLV Theses, Dissertations, Professional Papers, and Capstones

The purpose of this study was to determine kinematic and marker placement reliability of the Leardini multisegment foot model (LMFM) for tracking foot kinematics during barefoot and shod running without alteration of footwear. Eleven participants, five males (25.6±5 yrs, 73±15.8 kg, 1.75±0.05m) and six females (22.5±2.9 yrs, 66.6±7.2 kg, 1.71±0.05 m) granted institutionally approved written consent to participate. Three-dimensional motion capture (10 Vicon T40-S cameras) was used to capture kinematic data at 200Hz. Kinetic data was captured with an in-ground force platform (Kistler Instruments AG, Switzerland Model 9281B 60x40cm, 2000Hz). Participants were instructed to run at 3.5m/s ±5%. Velocity was …