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Full-Text Articles in Life Sciences
Identification Of Three Novel Genes, Ppk12, Ppk23, And Ppk25, Involved In Noxious Cold Detection In Drosophila, Benjamin Williamson
Identification Of Three Novel Genes, Ppk12, Ppk23, And Ppk25, Involved In Noxious Cold Detection In Drosophila, Benjamin Williamson
Masters Theses, 2010-2019
The reflexive response and perception of pain (nociception) is an evolutionarily conserved process in animals. Pain can be a major health concern and current treatments often prove insufficient, especially in regards to chronic pain. Greater understanding of the molecular processes underlying pain sensation could lead to new and more effective treatments. The aim of this study is to investigate the molecular mechanisms of cold nociception in Drosophila melanogaster. A specific subset of peripheral sensory neurons (Class III dendritic arborization (da) neurons), are implicated in Drosophila larvae’s response to noxious cold.
Previous literature has implicated a variety of ion channel families, …
Sleep Deprivation And Voluntary Alcohol Consumption In Adolescent Rats, Sancho N. Sequeira
Sleep Deprivation And Voluntary Alcohol Consumption In Adolescent Rats, Sancho N. Sequeira
Masters Theses, 2010-2019
Alcohol is one of the most common psychoactive drugs, and has been used by humans for thousands of years. Research has focused on the effects of alcohol on sleep, however recent trends in the literature have taken a more bidirectional approach to the relationship between alcohol and sleep. This research investigates the effects of chronic, partial sleep deprivation on alcohol consumption. Twelve adolescent Sprague Dawley rats had free access to two bottles at all times, one containing water and one containing a 7% alcohol and water solution. Sleep deprivation was achieved by using a forced exercise wheel. All rats were …