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Full-Text Articles in Life Sciences

Host Species Restriction Of Middle East Respiratory Syndrome Coronavirus Through Its Receptor, Dipeptidyl Peptidase 4, Neeltje Van Doremalen, Kerri L. Miazgowicz, Shauna Milne-Price, Trenton Bushmaker, Shelly Robertson, Dana Scott, Joerg Kinne, Jason S. Mclellan Jun 2014

Host Species Restriction Of Middle East Respiratory Syndrome Coronavirus Through Its Receptor, Dipeptidyl Peptidase 4, Neeltje Van Doremalen, Kerri L. Miazgowicz, Shauna Milne-Price, Trenton Bushmaker, Shelly Robertson, Dana Scott, Joerg Kinne, Jason S. Mclellan

Dartmouth Scholarship

Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012. Recently, the MERS-CoV receptor dipeptidyl peptidase 4 (DPP4) was identified and the specific interaction of the receptor-binding domain (RBD) of MERS-CoV spike protein and DPP4 was determined by crystallography. Animal studies identified rhesus macaques but not hamsters, ferrets, or mice to be susceptible for MERS-CoV. Here, we investigated the role of DPP4 in this observed species tropism. Cell lines of human and nonhuman primate origin were permissive of MERS-CoV, whereas hamster, ferret, or mouse cell lines were not, despite the presence of DPP4. Expression of human DPP4 in nonsusceptible BHK and …


The Long Haul: Risks Associated With Livestock Transport, Michael Greger May 2014

The Long Haul: Risks Associated With Livestock Transport, Michael Greger

Michael Greger, MD, FACLM

The Food and Agriculture Organization (FAO) of the United Nations describes live animal transport as “ideally suited for spreading disease,” given that animals may originate from different herds or flocks and are “confined together for long periods in a poorly ventilated stressful environment.” Given the associated “serious animal and public health problems,” the Federation of Veterinarians of Europe has called for the replacement of the long-distance transportation of live animals for slaughter as much as possible to a “carcass-only trade.” In the United States, more than 50 million live cattle, sheep, and pigs and an unknown number of the more …


Herbivory Strains Resilience In Drought-Prone Aspen Landscapes Of The Western United States, Paul C. Rogers Apr 2014

Herbivory Strains Resilience In Drought-Prone Aspen Landscapes Of The Western United States, Paul C. Rogers

Aspen Bibliography

Aims: Aspen forests around the northern hemisphere provide rich biodiversity compared to surrounding vegetation types. In both North America and Europe, however, aspen are threatened by a variety of human impacts: clear-felling, land development, water diversions, fire suppression, and both wild and domestic ungulate herbivory. We conducted a landscape assessment of quaking aspen (Populus tremuloides) for the purpose of identifying key components of resilience. Specifically, we strove to test novel measures linking plant-animal interactions, compare crucial functional differences in aspen types, and make appropriate restorative recommendations based on the outcome of these assessments. Location: The Book Cliffs region of eastern …


Integrating Teff Into Livestock Operations, Allen Young, Earl Creech, Dale Zobell, Clark Israelsen, Jong-Su Eun Feb 2014

Integrating Teff Into Livestock Operations, Allen Young, Earl Creech, Dale Zobell, Clark Israelsen, Jong-Su Eun

All Current Publications

This fact sheet describes teff, a relatively new forage crop that is attracting interest. Teff can be harvested multiple times during a growing season, used as emergency forage, has potential for double cropping and grazing.


Economic Impact Of The Potential Spread Of Vampire Bats Into South Texas, Aaron M. Anderson, Steven S. Shwiff, Stephanie A. Shwiff Jan 2014

Economic Impact Of The Potential Spread Of Vampire Bats Into South Texas, Aaron M. Anderson, Steven S. Shwiff, Stephanie A. Shwiff

USDA Wildlife Services: Staff Publications

Rabies transmitted by the common vampire bat is a major public health concern in subtropical and tropical areas of Latin America, and there is some concern that the species will eventually spread into south Texas. The objective of this study was to estimate the total economic impact of the potential spread of vampire bats into south Texas. Data on livestock populations and values in the relevant counties was combined with expected mortality rates to calculate livestock losses. An IMPLAN model of the regional economy was then used to estimate the secondary impacts experienced by other businesses in the region. These …