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Full-Text Articles in Life Sciences
The Effect Of Thymidylate Synthase Inhibitors On Bone Marrow Derived Cells In The Intestinal Tumor Microenvironment, Grishma Acharya
The Effect Of Thymidylate Synthase Inhibitors On Bone Marrow Derived Cells In The Intestinal Tumor Microenvironment, Grishma Acharya
Theses and Dissertations
Tumors have come to be known as independently functioning complex organs consisting of cancer cells coexisting with a heterogeneous mixture of host-derived non-neoplastic cells that form the tumor stroma. Tumor survival, progression, and metastasis depend on multiple close interactions between the cancer cells and the tumor stromal cells. These tumor stromal cells are mainly bone marrow derived cells (BMDCs) that are recruited to the primary tumor and sites of metastasis by a variety of signals secreted by the cancer cells. Because of the close interaction between the tumor and the tumor stroma, we propose that tumor stromal cells play an …
Quantifying The Effects Of Antibiotics Upon Benthic Diatoms And Marine Benthic Algal Communities, Isaac M. Hagenbuch
Quantifying The Effects Of Antibiotics Upon Benthic Diatoms And Marine Benthic Algal Communities, Isaac M. Hagenbuch
Theses and Dissertations
Antibiotics are a cornerstone of modern medicine. Their ability to impair prokaryotic metabolism has saved the lives of many millions of humans in the decades since wide antibiotic usage began. Antibiotic compounds are also widely used in the husbandry of animals that are used for food but, unfortunately, much of the antibiotic mass that goes into humans and animals is excreted unchanged. Those excretions go, directly or indirectly, into aquatic ecosystems. The discovery of this fact has led to a growing global concern about the fate of antibiotics in the environment. This concern is driven by no fewer than three …